What is TEXAS CHRISTIAN UNIVERSITY's OSHA violation history?

TEXAS CHRISTIAN UNIVERSITY has 2 OSHA inspections on record with 3 violations and $1,950 in total penalties.

How does TEXAS CHRISTIAN UNIVERSITY's safety record compare to its industry?

TEXAS CHRISTIAN UNIVERSITY operates in the colleges, universities, and professional schools industry. The industry average Total Recordable Incident Rate (TRIR) is 1.5.

Establishment profile

TEXAS CHRISTIAN UNIVERSITY

2800 S. UNIVERSITY DRIVE, FORT WORTH, TX, 76129
611310 — Colleges, Universities, and Professional Schools

Download as PDF →

OSHA inspections

over 36 years

Violations

$1,950 in penalties

Penalties

$1,950

$650 avg

Violations across 2 federal agencies

Enforcement actions from multiple agencies may indicate systemic compliance issues across functions.

Summary

TEXAS CHRISTIAN UNIVERSITY has accumulated 3 OSHA violations across 2 inspections over 36 years of recorded history, with $1,950 in total assessed penalties.

The establishment sits in the 65th percentile for violations within its industry-state peer group of 113,792 employers. Inspection frequency runs at the 81st percentile. The most recent enforcement activity was recorded 32 years ago.

Federal records were found in 2 of 15 sources. Sources without matching records returned empty for this establishment.

Agency coverage

TEXAS CHRISTIAN UNIVERSITY appears in OSHA workplace safety, NLRB labor relations, and OFLC visa and labor certification (historical) records only. No matching records were found in WHD wage enforcement, MSHA mine safety, EPA environmental compliance, FMCSA motor carrier registration, SAM.gov federal debarment, CMS nursing home enforcement, UVA Corporate Prosecution Registry, CPSC product recalls, or NHTSA vehicle recalls.

OSHA workplace safety

Inspections

0.1 / yr · last 36 yrs

Violations

0.1 / yr

Penalties

$1,950

$650 avg / violation

67% serious33% other

Inspection trigger · complaint

2 of 2

50% of inspections at this establishment produced violations,

Most-cited OSHA standards

Top OSHA standards cited at this employer, ranked by citation count. Standards (CFR sections) cluster citations into safety themes -- machine guarding, lockout-tagout, hazard communication, fall protection, process safety, etc. A concentration on one or two sections reveals a pattern that individual citations don’t. 3 distinct standards shown · 3 citations in this view · $1,950 in penalties.

CFR section	Citations	Inspections	Total penalty	First cited	Last cited
29 CFR 1910.1200 G09	1	1	$975	Dec 1993	Dec 1993
29 CFR 1910.1200 H01 I	1	1	$975	Dec 1993	Dec 1993
29 CFR 1910.1200 E01 I	1	1	—	Dec 1993	Dec 1993

Source: OSHA inspection citations (violation_detail). CFR section codes can be looked up at osha.gov/laws-regs for the formal standard text. Per-inspection detail and the specific violation descriptions are available by expanding individual inspections below.

Peer comparison

65th

Above average violations in NAICS 6113 within TX. Peer group: 113,792 employers. This establishment has 3 OSHA violations; peer median is 1.

Fewer violationsMore violations

Penalty percentile

93rd

peer median: $0

Inspection frequency

81st

peer median: 1

Safety self-report (OSHA 300A)

No self-reported injury rates filed with OSHA's Injury Tracking Application for TEXAS CHRISTIAN UNIVERSITY. Verify directly with OSHA Injury Tracking Application →

Industry benchmark

Industry avg TRIR

1.5

BLS SOII 2024

Industry avg DART

0.7

BLS SOII 2024

Self-reported TRIR

—

Not in OSHA ITA

BLS rates reflect industry-wide averages. Self-reported figures come from OSHA’s Injury Tracking Application; absence of self-reported data does not necessarily indicate non-compliance — many establishments fall below the ITA reporting threshold.

Inspection breakdown

Complaint

Complaint- and accident-triggered inspections are stronger risk signals than routine planned inspections.

OSHA severe injury reports

Self-reported events under 29 CFR 1904.39 (24-hour notification of hospitalization, amputation, or loss of an eye) · May 2018 – Feb 2021 · 1 in last 5 years

Reports

Hospitalizations

Amputations

Eye losses

Most frequent event: Contact with objects and equipment, n.e.c.

Source: OSHA Severe Injury Reports (federal OSHA only; state-plan states like California, Oregon, and Washington maintain their own programs and do not consistently report into this feed).

Severe injury reports — events

Each row is a hospitalization, amputation, or eye-loss event the employer self-reported to OSHA under 29 CFR 1904.39. Narratives are written by the reporting employer.

Date	Event	Body part	Outcome
Feb 15, 2021	Contact with objects and equipment, n.e.c.	Ankle(s)	Hospitalized
May 31, 2018	Fall from collapsing structure or equipment 21 to 25 feet	Multiple trunk locations	Hospitalized

Source: OSHA Severe Injury Reports. Federal-OSHA jurisdiction only by default; some state-plan programs report voluntarily.

Activity timeline

Data refreshed

Weekly

First OSHA inspection

—

Most recent activity

32 years ago

No federal enforcement activity has been recorded against this establishment in 32+ years. Most recent activity: 32 years ago. Data on this page is refreshed weekly.

Wage & Hour Division (WHD)

No WHD wage, overtime, or child-labor enforcement cases on file for TEXAS CHRISTIAN UNIVERSITY. Verify directly with Wage and Hour Division →

Mine safety (MSHA)

No MSHA mine safety violations on file for TEXAS CHRISTIAN UNIVERSITY. Verify directly with Mine Safety and Health Administration →

Labor relations (NLRB)

Company-level in TX — for TEXAS CHRISTIAN UNIVERSITY, not this location alone

Total cases

Unfair labor practice

National Labor Relations Board — unfair labor practice charges and union representation cases. The NLRB records cases at the company/regional level (no worksite address), so these are matched by company name and state and may span other TEXAS CHRISTIAN UNIVERSITY locations in the same state.

NLRB cases

National Labor Relations Board cases involving this employer. Includes unfair labor practice (ULP) filings and representation election proceedings. NLRB enforcement is process-driven; no per-case monetary penalty is assessed (remedies are case-by-case backpay orders, posting requirements, election re-runs, etc.). 4 cases · 4 ULP

Case number	Type	Filed	Closed	Status	Region
16-CA-364368	Unfair labor practice	Apr 2025	—	Open	Region 16, Fort Worth, Texas
16-CA-357784	Unfair labor practice	Jan 2025	—	Open	Region 16, Fort Worth, Texas
16-CA-341534	Unfair labor practice	May 2024	Jul 2025	Closed	Region 16, Fort Worth, Texas
16-CA-128032	Unfair labor practice	May 2014	Dec 2014	Closed	Region 16, Fort Worth, Texas

Source: NLRB case files. Rows shown are those the agency has published. Region numbers (1–31) correspond to NLRB's geographic offices.

Visa & labor certification (OFLC) — historical

Total applications

Certified

Avg wage ratio

1.16x

H-1B

Office of Foreign Labor Certification — labor condition applications for H-1B, H-2A, H-2B visa programs. Wage ratio = offered / prevailing wage. Historical data only: DOL ended OFLC Performance Data Disclosure publication in 2026, so the figures above reflect filings through the last ingested cycle and are not being refreshed. Treat as a historical snapshot, not a current signal.

Environmental compliance (EPA)

No EPA inspections or formal enforcement actions on file for TEXAS CHRISTIAN UNIVERSITY. Verify directly with Environmental Protection Agency →

EPA-registered facilities

Every EPA ECHO facility associated with this employer, sorted most-significant first. Each row links to EPA’s Detailed Facility Report for the source-of-truth record. Permits column lists active programs (Air = Clean Air Act, Water = Clean Water Act, RCRA = hazardous waste, TRI = Toxics Release Inventory reporting). 1 facility.

Facility	Permits	Status	Inspections	Formal actions	Penalties	Last inspected	ECHO
TEXAS CHRISTIAN UNIVERSITY 2800 S UNIVERSITY · FORT WORTH, TX, 76129	RCRA	No Violation Identified	0	0	—	—	View →

Source: EPA ECHO (Enforcement and Compliance History Online). Compliance status follows EPA’s own labels (“Sig Violation” = significant noncompliance; QNCR = quarters of noncompliance over the recent reporting window). Inactive facilities (struck through) retain historical enforcement records even after operations ceased.

Federal criminal prosecution record

No federal criminal prosecutions, plea agreements, or deferred-prosecution agreements on file for TEXAS CHRISTIAN UNIVERSITY. Verify directly with UVA Corporate Prosecution Registry →

Federal contracts

This location

Obligated (5-yr)

$9.2M

Obligated (all-time)

$11.5M

Awards

Top agency

Department of Justice

$11.2M

Top agencies by obligation (this location)

Department of Justice$11.2M

Department of Defense$346K

Department of Agriculture$23K

National Aeronautics and Space Administration$16K

Department of Health and Human Services$0

Largest awards

Department of Education
GRANT PROGRAM
assistance · Last action 2026-05-12
$13,960,328
Department of Health and Human Services
CENTER FOR THE ADAPTATION AND IMPLEMENTATION OF TRUST-BASED RELATIONAL INTERVENTION (TBRI) - THE CENTER FOR THE ADAPTATION AND IMPLEMENTATION OF TRUST-BASED RELATIONAL INTERVENTION® (TBRI®) WILL PROVIDE NATIONAL EXPERTISE IN TRAINING AND IMPLEMENTATION OF AN INTEGRATED TRAUMA TREATMENT AND SERVICE MODEL AND SUPPORT THE CONTINUUM OF CARE FOR CHILDREN, YOUTH, AND FAMILIES SERVED BY CHILD WELFARE AND JUVENILE JUSTICE WITH SPECIALIZED ADAPTATIONS OF THE TBRI MODEL. THE KARYN PURVIS INSTITUTE OF CHILD DEVELOPMENT (KPICD) AT TEXAS CHRISTIAN UNIVERSITY, IN PARTNERSHIP WITH THE CHILDREN’S TRAUMA ASSESSMENT CENTER (CTAC) AT WESTERN MICHIGAN UNIVERSITY, IS UNIQUELY POSITIONED TO ADDRESS TRAUMA AMONG CHILDREN AND YOUTH THROUGH WORKFORCE DEVELOPMENT, IMPLEMENTATION SUPPORT, AND STAKEHOLDER ENGAGEMENT. THE PROJECT WILL UTILIZE TBRI, A HOLISTIC, EVIDENCE-BASED MODEL OF CARE GROUNDED IN ATTACHMENT AND NEURODEVELOPMENTAL TRAUMA THAT EFFECTIVELY REDUCES TRAUMA SYMPTOMS AND IMPROVES BEHAVIORAL OUTCOMES IN CHILDREN (PURVIS ET AL., 2015). THE POPULATION TO BE SERVED CONSISTS OF THE WORKFORCE IN THE FOLLOWING SERVICE SETTINGS: FOSTER CARE/ADOPTION PRESERVATION, CAREGIVER TRAINING/SUPPORT, CONGREGATE CARE, JUVENILE JUSTICE FACILITIES/SERVICES, PROBATION, AND FAMILY COURTS. THESE DISTINCT YET OVERLAPPING SECTORS WILL BE THE RECIPIENTS OF DIRECT SERVICES SUCH AS SPECIALIZED PRODUCT DEVELOPMENT, TRAINING, CONSULTATION, AND IMPLEMENTATION SUPPORT DESIGNED TO EQUIP THE WORKFORCE TO RECOGNIZE AND RESPOND TO TRAUMA IN CHILDREN AND YOUTH. THE KPICD AND CTAC WILL DEVELOP AND TRAIN PROFESSIONALS IN AN INTEGRATED TRAUMA TREATMENT AND SERVICE MODEL WITH THE OBJECTIVE OF PRODUCING A STANDARDIZED PROTOCOL BY END OF YEAR 1 TO DELIVER TO PRACTITIONERS IN THE FIELD IN YEARS 2 THROUGH 5. TO FACILITATE PROGRAM SUSTAINABILITY AND FIDELITY, REFLECTIVE CONSULTATION WILL BE PROVIDED WITH THE FOLLOWING OBJECTIVES: (1) DEVELOP A CONSULTATION RESOURCE HANDBOOK AND (2) HIRE AND TRAIN CONSULTANTS FROM TARGET SERVICE SECTORS. TO EXPAND TRAUMA-INFORMED TRAINING TO HISTORICALLY UNDERSERVED COMMUNITIES, WE WILL (1) PARTNER WITH THE DINE’ (NAVAJO NATION) TRAUMA PROJECT TO CO-CREATE AN INDIGENOUS HOLISTIC HEALING MODEL AND SUPPORT TRAUMA TRAINING AND IMPLEMENTATION TO INDIGENOUS COMMUNITIES AND (2) LAUNCH AN INCLUSIVENESS INITIATIVE TO INCORPORATE AND ENGAGE A DIVERSE RANGE OF VOICES AND LIVED EXPERIENCES IN RESOURCE DEVELOPMENT AND SERVICE DELIVERY WITH A FOCUS ON IMPROVING EQUITY, INCLUSIVENESS, AND ACCESSIBILITY. TO PROMOTE STRATEGIC COLLABORATION AND TO EQUIP THE WORKFORCE, WE WILL (1) PROVIDE NCTSN COLLABORATIVE MEMBERS WITH TBRI TRAINING AND CONSULTATION, AND (2) PARTNER WITH STAKEHOLDERS FROM CHILD- AND YOUTH-SERVING ORGANIZATIONS TO DEVELOP SPECIALIZED ADAPTATIONS OF TBRI TRAINING MATERIALS AND RESOURCES TO MEET THE NEEDS OF DISTINCT SERVICE SETTINGS AND AUDIENCES. UTILIZING THE COMBINED ANTICIPATED TRAINING AND OUTREACH OPPORTUNITIES OF THE KPICD AND CTAC, WE EXPECT PROJECT IMPACT ON A NATIONAL SCALE. THIS INCLUDES 3,000 PRACTITIONERS FROM ACROSS THE U.S. TRAINED IN TBRI PRACTITIONER TRAINING (750 ANNUALLY IN YEARS 2-5), 800 INDIVIDUALS TRAINED IN INDIGENOUS COMMUNITIES THROUGH THE DINE’ TRAUMA PROJECT (200 ANNUALLY IN YEARS 2-5), AND 30 PROFESSIONALS TRAINED THROUGH COLLABORATION WITH NCTSN MEMBERS.
assistance · Last action 2026-01-15
$2,398,580
Department of Justice
DRUG ABUSE PROGRAMS EVALUATION
contract · Last action 2026-03-11
$2,232,987
Department of Education
PROJECT INTERSECT - PREPARING SLP LEADERS AT THE INTERSECTION OF RESEARCH AND PRACTICE IN CSD AND SPECIAL EDUCATION TO ADVANCE THE NEXT GENERATION OF SCHOOL SLPS (CFDA 84.325D)
assistance · Last action 2025-09-22
$2,226,525
Department of Justice
DRUG ABUSE PROGRAMS EVALUATION
contract · Last action 2024-06-13
$2,185,643
Department of Justice
DRUG ABUSE PROGRAMS EVALUATION
contract · Last action 2023-07-13
$1,908,721
Department of Justice
DRUG ABUSE PROGRAMS EVALUATION
contract · Last action 2022-09-26
$1,904,079
Department of Justice
DRUG ABUSE PROGRAMS EVALUATION
contract · Last action 2021-09-24
$1,876,562
Department of Education
TCU STUDENT SUPPORT SERVICES
assistance · Last action 2024-07-12
$1,554,667
Department of Education
TCU SSS STEM
assistance · Last action 2026-03-18
$1,329,451
Department of Education
TEXAS CHRISTIAN UNIVERSITY MCNAIR POST-BACCALAUREATE PROGRAM GRANT PROPOSAL
assistance · Last action 2025-09-22
$1,208,162
Department of Health and Human Services
TARGETING OXIDATIVE STRESS IN NEURODEGENERATION USING PYRIDOL-DERIVED SMALL MOLECULES
assistance · Last action 2026-04-01
$1,164,859
Department of Education
TCU UPWARD BOUND PROGRAM
assistance · Last action 2024-05-15
$885,613
Department of Education
CAMPUS BASED-FWS
assistance · Last action 2026-03-20
$826,869
National Science Foundation
IMPACT OF DIFFERENT LEARNING MODALITIES ON SCIENCE AND MATHEMATICS TEACHERS' EFFECTIVENESS AND RETENTION DURING THE COVID-19 PANDEMIC -THIS PROJECT AIMS TO SERVE THE NATIONAL NEED TO UNDERSTAND HOW DISTRICTS? DECISIONS ABOUT SCHOOL OPENINGS DURING COVID-19 IMPACTED STUDENTS AND SCIENCE AND MATH TEACHERS IN HIGH-NEED SCHOOL DISTRICTS. THREE LEARNING MODALITIES (E.G., IN-PERSON, REMOTE, HYBRID) RELATED TO TEACHING EFFECTIVENESS AND RETENTION WILL BE INVESTIGATED. DISTRICT AND SCHOOL LEVEL DATA WILL BE USED TO DETERMINE TEACHER EFFECTIVENESS AND TEACHER RETENTION DURING AND IMMEDIATELY AFTER THE COVID-19 SCHOOL CLOSURES. IN ADDITION, MATH AND SCIENCE TEACHER SELF-EFFECTIVENESS AND JOB SATISFACTION WILL BE STUDIED IN RELATION TO THE LEARNING MODALITIES. THIS PROJECT AT TEXAS CHRISTIAN UNIVERSITY INCLUDES A PARTNERSHIP WITH THE INSTITUTE FOR BIOMEDICAL PHILOSOPHY AND SELECTED HIGH-NEED SCHOOL DISTRICTS FROM ACROSS THE NINE CENSUS REGIONS OF THE U.S. THE OVERALL GOAL OF THIS PROJECT IS TO UNDERSTAND (A) IMPLEMENTATION OF LEARNING MODALITIES UTILIZED DURING THE PROTRACTED NATIONAL EMERGENCY OF COVID-19 AND (B) THE IMPACT OF THESE DIFFERENT MODALITIES ON STEM TEACHER EFFECTIVENESS AND RETENTION. THE THREE RESEARCH QUESTIONS ARE: (1) WHAT LEARNING MODALITIES WERE USED BY HIGH-NEED SCHOOL DISTRICTS BEGINNING IN FALL 2020 THROUGH SPRING 2022? (2) HOW DID UTILIZATION OF DIFFERENT LEARNING MODALITIES WITHIN A COVID-19 DICTATED TEACHING ENVIRONMENT CONTRIBUTE TO STEM TEACHER EFFECTIVENESS AND STEM TEACHER RETENTION IN HIGH-NEED SCHOOL DISTRICTS? AND (3) WHAT SUPPORT SYSTEMS AND RESOURCES WITHIN A COVID-19 DICTATED TEACHING ENVIRONMENT CONTRIBUTE TO STEM TEACHER EFFECTIVENESS AND STEM TEACHER RETENTION IN HIGH-NEED SCHOOL DISTRICTS? THE PROJECT WILL UTILIZE SECONDARY DATA FROM LARGE PUBLIC DATA SETS FOR RESEARCH QUESTIONS 1 AND 2 AS WELL AS THE SELECTION OF HIGH-NEED SCHOOL DISTRICTS. TWO-HUNDRED RESPONDENTS WILL PROVIDE DATA. THERE WILL BE THREE CASE STUDIES BOUNDED BY THE MODALITY THAT WILL EXPLORE THE COMMONALITIES WITHIN EACH CASE ASSOCIATED WITH THE THIRD RESEARCH QUESTION. FINDINGS ON BEST PRACTICES REGARDING TEACHER EFFECTIVENESS AND RETENTION, ESPECIALLY IN HIGH-NEED SCHOOL DISTRICTS, HAS THE POTENTIAL TO BE USED TO INFORM POLICY, PRACTICE, AND FUTURE DESIGN OF TEACHER PROFESSIONAL DEVELOPMENT. THIS TRACK 4: NOYCE RESEARCH PROJECT IS SUPPORTED THROUGH THE ROBERT NOYCE TEACHER SCHOLARSHIP PROGRAM (NOYCE). THE NOYCE PROGRAM SUPPORTS TALENTED STEM UNDERGRADUATE MAJORS AND PROFESSIONALS TO BECOME EFFECTIVE K-12 STEM TEACHERS AND EXPERIENCED, EXEMPLARY K-12 TEACHERS TO BECOME STEM MASTER TEACHERS IN HIGH-NEED SCHOOL DISTRICTS. IT ALSO SUPPORTS RESEARCH ON THE EFFECTIVENESS AND RETENTION OF K-12 STEM TEACHERS IN HIGH-NEED SCHOOL DISTRICTS. THIS AWARD REFLECTS NSF'S STATUTORY MISSION AND HAS BEEN DEEMED WORTHY OF SUPPORT THROUGH EVALUATION USING THE FOUNDATION'S INTELLECTUAL MERIT AND BROADER IMPACTS REVIEW CRITERIA.
assistance · Last action 2025-06-25
$743,229
Department of Health and Human Services
DISRUPTING PROTEIN-PROTEIN INTERACTIONS WITH SELF-ASSEMBLING MACROCYCLES
assistance · Last action 2024-01-09
$735,980
Department of Health and Human Services
A RANDOMIZED CONTROLLED TRIAL OF COMPUTER-ASSISTED BILINGUAL VOCABULARY INTERVENTION IN EMERGENT BILINGUALS WITH DEVELOPMENTAL LANGUAGE DISORDER - PROJECT SUMMARY/ABSTRACT OVER 45 MILLION PEOPLE IN THE U.S. SPEAK SPANISH AT HOME, YET ONLY ~5% OF SPEECH-LANGUAGE PATHOLOGISTS PROVIDE SPANISH-LANGUAGE SERVICES. THIS CRITICAL SHORTAGE LEAVES MANY EMERGENT BILINGUAL CHILDREN WITH DEVELOPMENTAL LANGUAGE DISORDER (DLD) WITHOUT ACCESS TO BILINGUAL INTERVENTIONS, CONTRIBUTING TO LONG-TERM DISPARITIES IN COMMUNICATION OUTCOMES. BILINGUAL INTERVENTION SUPPORTS ROBUST LANGUAGE GROWTH IN BOTH SPANISH AND ENGLISH WITH NO LOSS OF ENGLISH GAINS, BUT IS OFTEN UNAVAILABLE DUE TO THE DEARTH OF BILINGUAL CLINICIANS, LEAVING KEY ASPECTS OF THESE CHILDREN'S LANGUAGE DEVELOPMENT UNADDRESSED. TO ADDRESS THIS GAP, WE PROPOSE A TECHNOLOGY-DRIVEN SOLUTION: THE COMPUTER-ASSISTED BILINGUAL VOCABULARY INTERVENTION (CABVI), AN APPROACH THAT ENABLES MONOLINGUAL CLINICIANS TO DELIVER STANDARDIZED, LINGUISTICALLY RICH BILINGUAL INSTRUCTION USING SPANISH AND ENGLISH STRATEGICALLY TO SUPPORT LEARNING AND CROSS-LINGUISTIC TRANSFER. CABVI USES INTERACTIVE, RESPONSIVE CONTENT TO SHIFT THE CLINICIAN'S ROLE FROM SOLE LANGUAGE PROVIDER TO FACILITATOR, EMPOWERING SLPS TO SUPPORT DUAL-LANGUAGE DEVELOPMENT IN EMERGENT BILINGUALS WITH DLD. OUR LONG-TERM GOAL IS TO REDUCE GAPS IN CARE FOR EMERGENT BILINGUALS DLDS BY LEVERAGING SUCH SCALABLE, TECHNOLOGY-BASED STRATEGIES TO EXPAND ACCESS TO BILINGUAL INTERVENTION. THE IMMEDIATE OBJECTIVE OF THIS R01 IS TO RIGOROUSLY EVALUATE CABVI'S EFFICACY AND ECOLOGICAL VALIDITY IN A RANDOMIZED CONTROLLED TRIAL. AIM 1 WILL DETERMINE WHETHER EMERGENT BILINGUALS WITH DLD CHILDREN RECEIVING BILINGUAL CABVI SHOW GREATER VOCABULARY GAINS IN SPANISH AND ENGLISH THAN PEERS RECEIVING MONOLINGUAL INTERVENTIONS (EITHER TRADITIONAL ENGLISH-ONLY THERAPY OR MONOLINGUAL CABVI). AIM 2 WILL COMPARE VOCABULARY GROWTH IN EMERGENT BILINGUALS WITH DLD CHILDREN VERSUS THEIR TYPICALLY DEVELOPING BILINGUAL PEERS AFTER CABVI TO UNDERSTAND HOW DEVELOPMENTAL LANGUAGE DISORDER INFLUENCES RESPONSE TO BILINGUAL INTERVENTION. AIM 3 WILL ASSESS THE PLATFORM'S REAL-WORLD FEASIBILITY BY EXAMINING MONOLINGUAL SLPS' FIDELITY TO THE INTERVENTION PROTOCOL, AS WELL AS THEIR SATISFACTION AND CONFIDENCE USING CABVI. PRELIMINARY FINDINGS UNDERSCORE CABVI'S PROMISE: A PILOT SCHOOL IMPLEMENTATION DEMONSTRATED THAT MONOLINGUAL PROVIDERS CAN FEASIBLY DELIVER CABVI WITH HIGH FIDELITY OVER SEVERAL MONTHS, AND CHILDREN RECEIVING BILINGUAL CABVI ACHIEVED SIGNIFICANT VOCABULARY GAINS IN BOTH SPANISH AND ENGLISH WHILE MAINTAINING PROGRESS IN ENGLISH COMPARABLE TO MONOLINGUAL INTERVENTION OUTCOMES. BY VALIDATING THIS SCALABLE, LINGUISTICALLY TAILORED INTERVENTION, THE PROJECT WILL IMPROVE ACCESS TO THIS POPULATION FOR APPROPRIATE THERAPY, ENHANCE THEIR BILINGUAL COMMUNICATION OUTCOMES, AND INFORM FUTURE SCALABLE CLINICAL MODELS THAT LEVERAGE TECHNOLOGY TO BRIDGE CLINICIAN-LANGUAGE GAPS - DIRECTLY ALIGNING WITH NIDCD PRIORITIES TO DEVELOP EVIDENCE-BASED INTERVENTIONS AND IMPROVE ACCESS TO EVIDENCE-BASED CARE FOR ALL AMERICANS.
assistance · Last action 2026-05-11
$530,054
National Science Foundation
COLLABORATIVE RESEARCH: CHEMICAL HISTORY OF THE MILKY WAY AS SEEN THROUGH OPEN CLUSTERS USING SDSS AND GAIA -THROUGHOUT THE HISTORY OF THE UNIVERSE GALAXIES CHANGE AND GROW. ASTRONOMERS ARE WORKING TO UNDERSTAND HOW THE CHEMICAL MAKE-UP OF THE STARS WITHIN GALAXIES CHANGE WITH TIME. BY MEASURING HOW, AND WHEN, SPECIFIC ELEMENTS INCREASE, THE INVESTIGATORS WILL CREATE 'CHEMICAL CLOCKS' THAT TRACE THE CHEMICAL CHANGES DURING THE LIFE OF THE MILKY WAY GALAXY. THIS RESEARCH TEAM WILL MEASURE THE CHEMICAL MAKEUP OF NEARLY ALL THE SUITABLE STAR CLUSTERS IN THE MILKY WAY DISK. THIS PROJECT WILL SERVE THE NATIONAL INTEREST AND PROMOTE THE PROGRESS OF RESEARCH IN ASTRONOMY BY PROVIDING A UNIQUE CATALOG THAT CAN BE USED TO PROBE THE HISTORY OF THE MILKY WAY. THE INVESTIGATORS WILL CARRY OUT MENTORING AND OUTREACH ACTIVITIES AT THE UNIVERSITY OF UTAH AND AT TEXAS CHRISTIAN UNIVERSITY'S MONNIG METEORITE GALLERY. THEY WILL ALSO TRAIN GRADUATE AND UNDERGRADUATE STUDENTS IN MODERN DATA SCIENCE RESEARCH AND ANALYSIS TECHNIQUES. USING HIGH-RESOLUTION SPECTROSCOPY FROM THE SLOAN DIGITAL SKY SURVEY V (SDSS-V) AND ASTROMETRY FROM THE GAIA SATELLITE, THIS RESEARCH TEAM WILL OBSERVE, COMPILE, AND ANALYZE A CATALOG OF OPEN STAR CLUSTERS. THIS CATALOG WILL BE REVOLUTIONARY IN ITS SIZE AND UNIFORMITY. ADDITIONAL HIGH-RESOLUTION OPTICAL SPECTROSCOPY WILL SUPPLEMENT THE SDSS-V DATA WITH NEUTRON-CAPTURE ELEMENTAL ABUNDANCES TO CREATE A UNIQUE CATALOG COMPRISING UP TO 90% OF THE GAIA-CONFIRMED OPEN STAR CLUSTERS WITH HOMOGENEOUS DATA, INCLUDING CONSISTENTLY MEASURED AGES, DISTANCES, REDDENING, DYNAMICS, AND DETAILED ABUNDANCES FOR MORE THAN 20 ELEMENTS. THIS DATA SET, WHICH WILL BE PUBLICLY RELEASED, WILL PROVIDE KEY CONSTRAINTS ON WHETHER CHEMICAL TAGGING CAN WORK IN THE MILKY WAY DISK, ON THE PARTICIPATION OF OPEN CLUSTERS IN RADIAL MIGRATION, AND ON SUPERNOVAE ELEMENT YIELDS. THE CATALOG WILL BE USED TO BETTER UNDERSTAND STELLAR FEEDBACK OVER TIME AND TEST COSMOLOGICAL MODELS OF GALAXIES LIKE OUR MILKY WAY. THIS AWARD REFLECTS NSF'S STATUTORY MISSION AND HAS BEEN DEEMED WORTHY OF SUPPORT THROUGH EVALUATION USING THE FOUNDATION'S INTELLECTUAL MERIT AND BROADER IMPACTS REVIEW CRITERIA.
assistance · Last action 2022-08-17
$455,321
Department of Health and Human Services
BIOCOMPATIBLE GRAPHENE QUANTUM DOTS FOR NONINVASIVE NEAR-INFRARED BIOIMAGING - PROJECT SUMMARY/ABSTRACT NEAR-INFRARED (NIR) IMAGING IS ONE OF THE MOST RAPIDLY DEVELOPING PERSPECTIVE TECHNIQUES IN BIOMEDICAL DIAGNOSTICS ENABLING 10 - 100 TIMES DEEPER TISSUE IMAGING THAN REGULAR VISIBLE FLUORESCENCE TECHNIQUES. THERE IS A SIGNIFICANT CLINICAL NEED FOR SUCH IMAGING: HIGH-DEPTH CT AND MRI IMAGING STRATEGIES ARE COMPLEX AND LESS SUITABLE FOR LOW-DEPTH BIOSENSING AND INTRAOPERATIVE APPLICATIONS. FURTHERMORE, IN ANIMAL STUDIES NIR IMAGING CAN ENABLE IN SITU FLUORESCENCE TRACKING OF TESTED THERAPEUTICS OR TUMOR VISUALIZATION INSIDE A LIVING SMALL ANIMAL. HOWEVER, AS NIR IMAGING FIELD IS STILL DEVELOPING, THERE IS A LACK OF BIOCOMPATIBLE AND MULTIFUNCTIONAL PLATFORMS SUITABLE FOR IMAGING, SENSING AND EVEN DRUG TRANSPORT HIGHLY DESIRED IN ANIMAL STUDIES. IN THIS PROJECT WE WILL DEVELOP AND TEST THE FEASIBILITY OF A NOVEL NIR IMAGING PLATFORM BASED ON GRAPHENE QUANTUM DOTS (GQDS) ADDRESSING THE CRITICAL NEEDS OF NIR BIOIMAGING: FLUORESCENCE IN THE NIR (ABOVE 950 NM) WITH NIR EXCITATION, HIGH BIOCOMPATIBILITY, PHOTOSTABILITY, AND CAPABILITIES FOR DRUG TRACING AND IN VIVO NIR IMAGING IN LIVE ANIMAL MODELS. THIS WILL BE IMPLEMENTED IN 3 STEPS: (1) SYNTHESIZING NIR-EMISSIVE GQDS VIA BOTTOM-UP AND TOP-DOWN APPROACHES AND CHARACTERIZING THEIR OPTICAL AND PHYSICAL PROPERTIES, (2) TESTING GQDS FOR NIR IN VITRO IMAGING AND ASSESSING THEIR BIOCOMPATIBILITY AND (3) PERFORMING IN VIVO IMAGING OF GQD NIR FLUORESCENCE IN LIVE ANIMALS AS WELL AS EX VIVO ORGAN TISSUE IMAGING QUANTIFYING GQD CONTENT IN EXCISED ORGANS. WE WILL CONCOMITANTLY ASSESS POTENTIAL ADVERSE EFFECTS TO SELECT NON-TOXIC GQD CANDIDATES. THROUGHOUT THIS PROCESS A VARIETY OF SYNTHESIZED GQD STRUCTURES WILL UNDERGO RIGOROUS 3-STEP SELECTION FOR THE CAPABILITIES OF (1) HIGH YIELD NIR FLUORESCENCE, (2) HIGH BIOCOMPATIBILITY AND NIR IMAGING IN CELLS, (3) NIR IMAGING INSIDE A LIVE SEDATED ANIMAL WITH MINIMAL/NO TOXICITY. THE SELECTED GQD CANDIDATES WILL ENABLE IN VIVO ANIMAL TESTING OF THERAPEUTIC DELIVERY WITH NONINVASIVE REAL-TIME IMAGE TRACKING REDUCING THE NUMBER OF ANIMALS SACRIFICED. IN A LONGER TERM, WE EXPECT THESE GQD PLATFORMS TO BECOME A BASIS OF THE NONINVASIVE NIR IN VIVO SENSING IN PATIENTS. AS A RESULT, THE PROPOSED INITIATIVE WILL ADDRESS SEVERAL SIGNIFICANT AREAS OF BIOTECHNOLOGY AND ITS DEVELOPMENT WILL ULTIMATELY CONTRIBUTE TO THE IMPROVEMENT OF HUMAN HEALTH.
assistance · Last action 2025-12-16
$410,136
Department of Health and Human Services
EXAMINING THE MEDIATING AND MODERATING FACTORS IN THE RELATIONSHIPS BETWEEN SOCIAL MEDIA ENGAGEMENT AND ENDS USE AND DEPENDENCE AMONG YOUNG ADULTS - PROJECT SUMMARY/ABSTRACT ELECTRONIC NICOTINE DELIVERY SYSTEMS (ENDS) USE BY YOUNG ADULTS HAS SUBSTANTIALLY INCREASED IN THE LAST FEW YEARS AND SURPASSED THAT OF OLDER ADULTS IN 2014. RECENT YEARS HAVE WITNESSED A SHIFT IN PROMOTION OF ENDS PRODUCTS FROM TRADITIONAL MEDIA TO SOCIAL MEDIA (SM). YOUNG ADULTS ARE HEAVY SM USERS, WHO ARE VULNERABLE TO PERSUASIVE ADVERTISING MESSAGES BECAUSE THEY MAY NOT BE ABLE TO RECOGNIZE THE SELLING INTENT OF WELL- PRODUCED SM ADVERTISING. MOREOVER, ADVERTISING OF ENDS PRODUCTS ON SM IS CURRENTLY UNREGULATED. YOUNG ADULTS ALSO ARE MORE LIKELY THAN ALL OTHER AGE GROUPS TO USE OTHER TOBACCO PRODUCTS (E.G., CIGARETTES, CIGARS) AND REPORT DEPRESSION; AND CLOSE PEERS CONTINUE TO INFLUENCE THEIR ENDS USE. ALTHOUGH THERE IS EVIDENCE THAT EXPOSURE TO AND ENGAGEMENT WITH ENDS INFORMATION ON SM ARE SIGNIFICANTLY ASSOCIATED WITH ENDS USE AMONG YOUNG ADULTS, THERE IS A PAUCITY OF MULTI-WAVE LONGITUDINAL RESEARCH EXAMINING THE MEDIATORS AND MODERATORS OF THESE ASSOCIATIONS. THERE IS A CRITICAL NEED FOR LONGITUDINAL RESEARCH TO A) EXAMINE THE COGNITIVE FACTORS THAT EXPLAIN, OR MEDIATE, THE ASSOCIATIONS BETWEEN EXPOSURE TO AND ENGAGEMENT WITH ENDS INFORMATION ON SM AND SUBSEQUENT ENDS USE AND DEPENDENCE (SM-ENDS ASSOCIATIONS), AND B) DETERMINE WHETHER THE MEDIATED ASSOCIATIONS VARY, OR ARE MODERATED, BY INTRA- OR INTERPERSONAL FACTORS TO GUIDE POLICY-MAKING AND ANTI-ENDS CAMPAIGN MESSAGE DESIGN. THUS, THE PRIMARY OBJECTIVE OF THIS R15 IS TO IDENTIFY THE MEDIATORS AND MODERATORS OF THE LONGITUDINAL ASSOCIATIONS BETWEEN SM AND SUBSEQUENT ENDS USE AND DEPENDENCE AMONG YOUNG ADULTS. BASED ON THE REASONED ACTION APPROACH, WE WILL EXAMINE COGNITIVE FACTORS (NORMATIVE BELIEFS, BENEFIT BELIEFS, AND HARM BELIEFS OF USING ENDS) AS MEDIATORS, AND INVESTIGATE INTRA-PERSONAL (I.E., SEX, OTHER TOBACCO USE, DEPRESSIVE SYMPTOMS) AND INTERPERSONAL (I.E., ENDS USE AMONG CLOSE FRIENDS) FACTORS AS MODERATORS. THE SPECIFIC AIMS OF THE PROPOSED PROJECTS ARE TO 1) IDENTIFY THE COGNITIVE MEDIATORS OF THE LONGITUDINAL SM-ENDS ASSOCIATIONS, AND 2) DETERMINE THE INTRA- AND INTER-PERSONAL MODERATORS OF THE INDIRECT ASSOCIATIONS BETWEEN EXPOSURE TO AND ENGAGEMENT WITH ENDS INFORMATION ON SM AND SUBSEQUENT ENDS USE AND DEPENDENCE ONE YEAR LATER THROUGH COGNITIONS. DATA FOR THE PROPOSED PROJECT WILL BE DRAWN FROM A THREE-WAVE, BI-ANNUAL LONGITUDINAL STUDY THAT TRACKS A NATIONALLY-REPRESENTATIVE COHORT OF 1,000 18-30-YEAR-OLDS YOUNG ADULTS. THIS PROJECT WILL SUPPORT AT LEAST ONE GRADUATE STUDENT AND THREE UNDERGRADUATE STUDENTS IN EACH OF THE THREE YEARS, WHO WILL RECEIVE TRAINING AND MENTORSHIP ON SYNTHESIZING LITERATURE, DESIGNING STUDIES, PROGRAMMING AND PILOT TESTING SURVEYS, ANALYZING DATA, AND REPORTING FINDINGS EFFECTIVELY IN ORAL AND WRITTEN FORMATS, WHICH WILL BENEFIT THEIR FUTURE CAREERS. IF SUCCESSFUL, THE FINDINGS WILL SERVE AS THE BASIS FOR A SUBSEQUENT R01 TO DESIGN AND EVALUATE SM-BASED ENDS CAMPAIGN MESSAGES TARGETING YOUNG ADULTS AND THE SIGNIFICANT MEDIATORS AND MODERATORS. YOUNG ADULTHOOD IS THE PERIOD WHEN THE PATHWAY TO LIFELONG TOBACCO USE IS ESTABLISHED. THE LONG- TERM GOAL IS TO PREVENT AND REDUCE ENDS USE AMONG YOUNG ADULTS BEFORE IT IS ESTABLISHED.
assistance · Last action 2024-11-29
$407,581
Department of Health and Human Services
THE ROLE OF FAMILY CONTEXTUAL FACTORS IN THE DEVELOPMENT OF EMOTION REGULATION IN YOUNG CHILDREN ON THE AUTISM SPECTRUM - PROJECT SUMMARY/ABSTRACT THE MAJORITY OF CHILDREN ON THE AUTISM SPECTRUM HAVE A CO-OCCURRING MENTAL HEALTH DISORDER AND EMOTION DYSREGULATION IS POSITED TO SERVE AS A RISK FACTOR FOR THE DEVELOPMENT OF MENTAL HEALTH DISORDERS. HOWEVER, REGULATING EMOTIONS IS A DYNAMIC PROCESS THAT IS INFLUENCED BY THE INTERPLAY OF CHILD CHARACTERISTICS AND THE FAMILY CONTEXT AND THERE IS A PAUCITY OF RESEARCH EXAMINING THESE PROCESSES IN CHILDREN ON THE AUTISM SPECTRUM. THE LONG-TERM GOAL IS TO REDUCE THE CO-OCCURRENCE OF MENTAL HEALTH DISORDERS IN CHILDREN ON THE AUTISM SPECTRUM. THE OVERALL OBJECTIVE IN THIS APPLICATION IS TO CLARIFY THE ASSOCIATIONS BETWEEN THE FAMILY CONTEXT AND CHILDREN’S DEVELOPMENT OF EMOTION REGULATION. THE CENTRAL HYPOTHESIS IS THAT THE STRENGTH AND DIRECTION OF THE ASSOCIATIONS BETWEEN THE FAMILY CONTEXT AND EMOTION REGULATION DEPEND UPON CHILDREN’S CHARACTERISTICS, INCLUDING AUTISM DIAGNOSTIC STATUS AND THE HETEROGENEITY OF AUTISM SYMPTOM SEVERITY. THE RATIONALE FOR THE PROPOSED RESEARCH IS THAT ONCE WE IDENTIFY CONTEXTUAL FACTORS ASSOCIATED WITH EMOTION REGULATION, AND FOR WHOM THEY ARE APPLICABLE TO, THEN WE CAN DEVELOP APPROPRIATE INTERVENTIONS TO REDUCE THE DEVELOPMENT OF CO-OCCURRING MENTAL HEALTH DISORDERS. THE CENTRAL HYPOTHESIS WILL BE TESTED BY PURSUING TWO SPECIFIC AIMS: 1) IDENTIFY WHETHER DYNAMICS OF EMOTION REGULATION DIFFER FOR CHILDREN ON THE AUTISM SPECTRUM COMPARED TO NON-ASD CHILDREN AND WHETHER, AMONG CHILDREN ON THE AUTISM SPECTRUM, SUCH DYNAMICS VARY AS A FUNCTION OF CHILD CHARACTERISTICS; AND 2) IDENTIFY THE EXTENT TO WHICH ASPECTS OF THE FAMILY CONTEXT, PREVIOUSLY IDENTIFIED IN NT CHILDREN, ARE ASSOCIATED WITH EMOTION REGULATION AND WHETHER CHILD CHARACTERISTICS MODERATE THESE ASSOCIATIONS. THE PI’S PRELIMINARY STUDIES INDICATE STRONG FEASIBILITY OF RECRUITING A SAMPLE OF YOUNG CHILDREN ON THE AUTISM SPECTRUM AND MEASURING EMOTION REGULATION. THE PROPOSED RESEARCH WILL INCLUDE 220 CHILDREN (110 ASD; 110 NON-ASD) AND THEIR PARENTS. THE PROPOSED RESEARCH IS INNOVATIVE, IN THE APPLICANT’S OPINION, BECAUSE IT REPRESENTS A SUBSTANTIVE DEPARTURE FROM THE STATUS QUO BY USING A MULTI-METHOD DESIGN TO UNDERSTANDING THE DYNAMICS OF EMOTION REGULATION IN CHILDREN ON THE AUTISM SPECTRUM AND IDENTIFYING WHICH CHILDREN ARE MOST AT RISK FOR DIFFICULTIES REGULATING EMOTIONS. THE PROPOSED RESEARCH IS SIGNIFICANT BECAUSE IT IS EXPECTED TO INFORM EFFORTS TO PROMOTE HEALTHY EMOTIONAL DEVELOPMENT IN CHILDREN ON THE AUTISM SPECTRUM.
assistance · Last action 2024-03-15
$391,233
Department of Justice
ANGER MANAGEMENT RESEARCH PROJECT NOTE: A SEPARATE TASK ORDER WILL BE ISSUED IN ADVANCE FOR ALL REQUIRED SERVICES.
contract · Last action 2023-05-30
$354,956
Department of Justice
ANGER MANAGEMENT RESEARCH PROJECT NOTE: A SEPARATE TASK ORDER WILL BE ISSUED IN ADVANCE FOR ALL REQUIRED SERVICES.
contract · Last action 2022-08-24
$351,972
Department of Justice
ANGER MANAGEMENT RESEARCH PROJECT NOTE: A SEPARATE TASK ORDER WILL BE ISSUED IN ADVANCE FOR ALL REQUIRED SERVICES.
contract · Last action 2021-09-08
$346,162
Department of Health and Human Services
TRANSLARYNGEAL VIBRATION FOR HYPERFUNCTIONAL VOICE DISORDERS - PROJECT SUMMARY / ABSTRACT HIGH-QUALITY RESEARCH DESIGNS HAVE DEMONSTRATED THAT VOICE THERAPY HAS A POSITIVE IMPACT ON HYPERFUNCTIONAL VOICE DISORDERS ASSOCIATED WITH MUSCLE TENSION DYSPHONIA (MTD). AMONG THE OPTIONS OF BEHAVIORAL VOICE THERAPY FOR MTD, ONE OF THE MOST EFFECTIVE EVIDENCE-BASED APPROACHES IS FLOW PHONATION (A.K.A., STRETCH-AND- FLOW VOICE THERAPY). HOWEVER, THE PHENOMENON OF POST-TREATMENT OUTCOME MEASURES REMAINING SUBSTANTIALLY OUTSIDE THE RANGE OF NORMAL IS A UBIQUITOUS FINDING IN STUDIES INVESTIGATING THIS AND OTHER VOICE THERAPY APPROACHES. FROM BOTH A COST BURDEN AND QUALITY OF LIFE PERSPECTIVE, THIS PHENOMENON SUPPORTS A NEED TO DEVELOP AND REFINE VOICE THERAPY TREATMENT APPROACHES TO PROMOTE BETTER OUTCOMES. VIBRATION IS A PHYSICAL MODALITY THAT HAS A HISTORICAL USE IN THE REHABILITATION PROFESSIONS, BUT ONLY RECENTLY HAS IT BEEN SCIENTIFICALLY STUDIED AS A MODALITY FOR VOICE THERAPY WHEN USED BY SPEECH-LANGUAGE PATHOLOGISTS. WHEN APPLIED LOCALLY ON THE PERILARYNGEAL SURFACE AS A LOCAL TRANSLARYNGEAL VIBRATION THERAPY (LTLV), EARLY RESEARCH HAS DEMONSTRATED BENEFICIAL EFFECTS ON VOICE PHYSIOLOGY AND CLINICAL OUTCOMES. FURTHER HIGH-QUALITY CLINICAL RESEARCH STUDIES ARE NEEDED TO EVALUATE THE EFFICACY OF LTLV AS A MODALITY FOR VOICE DISORDERS AND TO BETTER UNDERSTAND THE EFFECTS OF VIBRATION AND EFFECTIVE VIBRATION DOSE ON VOICE REHABILITATION OUTCOMES. THE RESEARCH PROPOSED IN THIS R15 HAS THE POTENTIAL TO TRANSFORM CLINICAL PRACTICE OF TREATMENT FOR MTD, THE MOST COMMON VOICE DISORDER AMONG TREATMENT-SEEKING POPULATIONS. THAT POTENTIAL IS VESTED IN THE PURSUIT OF THREE SPECIFIC AIMS: (1) DETERMINE THE CLINICAL EFFICACY OF LTLV AS A CONCURRENT TREATMENT USING FLOW PHONATION VOICE THERAPY IN PATIENTS WITH MTD, AND (2) DETERMINE THE EFFECT OF TREATMENT DOSE ON CLINICAL RESPONSE ASSOCIATED WITH TREATMENT OUTCOMES. IN ADDITION TO THE POTENTIAL IMPACT OF THIS R15, THE INNOVATIVE OF APPROACH OF USING LTLV AS A CONCURRENT MODALITY WITH FLOW PHONATION COMBINED WITH INVESTIGATION OF THE MOST EFFECTIVE FREQUENCY PARAMETER FOR CLINICAL APPLICATION REPRESENTS A PIONEERING APPROACH TO ADVANCE THE FIELD OF CLINICAL VOICE PRACTICE IN SPEECH-LANGUAGE PATHOLOGY.
assistance · Last action 2026-02-20
$340,417
Department of Health and Human Services
INDUCTION OF PROTECTIVE IMMUNE RESPONSES AGAINST C. NEOFORMANS IN IMMUNE COMPROMISED HOSTS - CRYPTOCOCCUS NEOFORMANS INFECTIONS ARE A SIGNIFICANT CAUSE OF MORBIDITY AND MORTALITY AMONG AIDS PATIENTS. CRYPTOCOCCAL MENINGOENCEPHALITIS IS THE MOST COMMON DISSEMINATED FUNGAL DISEASE IN AIDS PATIENTS AND IS RESPONSIBLE FOR 15% OF AIDS-RELATED DEATHS GLOBALLY. BECAUSE HOST IMMUNE RESPONSES ARE SO VITAL TO THE CONTROL OF CRYPTOCOCCOSIS, THE OVERALL OBJECTIVE OF OUR LABORATORY IS TO DETERMINE THE MECHANISM(S) NECESSARY TO ELICIT PROTECTIVE IMMUNITY AGAINST C. NEOFORMANS INFECTIONS IN IMMUNE DEFICIENT HOSTS. TO THIS END, STUDIES IN OUR LABORATORY EMPLOY A C. NEOFORMANS STRAIN ENGINEERED TO EXPRESS INTERFERON (IFN)-, DESIGNATED H99, AS A MODEL SYSTEM TO DEFINE PROTECTIVE IMMUNE RESPONSES AGAINST C. NEOFORMANS. PUBLISHED STUDIES BY OUR LAB DEMONSTRATED THAT IMMUNIZATION WITH H99 INDUCES PROTECTIVE IMMUNITY AGAINST CRYPTOCOCCOSIS IN MICE ALTOGETHER DEFICIENT IN B CELLS, CD4+ T CELLS, CD8+ T CELLS, NK CELLS AND NEUTROPHILS. PRELIMINARY RESULTS PROVIDED HEREIN SUGGEST THAT CONVENTIONAL DC1 CELLS (CDC1S) ARE CRITICAL FOR THE DEVELOPMENT OF MACROPHAGE ANTI- MICROBIAL ACTIVITY, OPTIMAL T CELL RESPONSES AND THE INDUCTION OF PROTECTIVE IMMUNITY AGAINST CRYPTOCOCCOSIS. TAKEN TOGETHER, OUR RESULTS LEAD US TO HYPOTHESIZE THAT CDC1S ARE CRITICAL FOR THE ELICITATION OF PROTECTIVE VACCINE-MEDIATED IMMUNE RESPONSES AGAINST CRYPTOCOCCOSIS IN CD4+ T CELL DEFICIENT HOSTS. THE FOUNDATION FOR OUR HYPOTHESIS IS SUPPORTED BY A SCIENTIFICALLY RIGOROUS SET OF PUBLISHED AND PRELIMINARY RESULTS THAT DEMONSTRATE THE POTENTIAL IMPACT OF STRATEGIES THAT PRIME CDC1S TO ELICIT PROTECTIVE IMMUNITY AGAINST CRYPTOCOCCOSIS IN IMMUNE DEFICIENT HOSTS. TO TEST OUR HYPOTHESIS, WE PROPOSE TO DEFINE THE MECHANISM(S) BY WHICH IFN- PRIMED CDC1S MEDIATE PROTECTIVE ANTI-CRYPTOCOCCUS IMMUNE RESPONSES IN IMMUNE COMPROMISED HOSTS.
assistance · Last action 2025-11-07
$335,939
Department of Education
TCU STUDENT SUPPORT SERVICES REGULAR PROJECT
assistance · Last action 2025-07-03
$318,278
National Science Foundation
APPLYING COMPUTATION TO MOLECULAR HINGES -WITH THE SUPPORT OF THE MACROMOLECULAR, SUPRAMOLECULAR AND NANOCHEMISTRY PROGRAM IN THE DIVISION OF CHEMISTRY, PROFESSOR ERIC SIMANEK OF TEXAS CHRISTIAN UNIVERSITY AIMS TO GAIN A BETTER UNDERSTANDING OF THE STRUCTURE-FUNCTION RELATIONSHIPS OF MOLECULAR HINGES. REMARKABLY, IN THE WORLD OF MOLECULAR MACHINES AND TOPOLOGIES, HINGES ARE LARGELY UNEXPLORED. THIS RESEARCH WILL DEVELOP COMPUTATIONAL MODELS TO PROVIDE INSIGHTS INTO AN EXPERIMENTAL TRAINING SET WHEREIN CONFORMATION AND DYNAMICS OF MOLECULAR HINGES ARE BOTH UNDERSTOOD, MEASURABLE AND TUNABLE. BROADER IMPACTS INCLUDE 1) INFORMING DESIGN OF NEW ORGANIC MATERIALS, AND 2) CROSS-TRAINING OF UNDERGRADUATE AND GRADUATE STUDENTS IN BOTH EXPERIMENTAL SYNTHETIC ORGANIC CHEMISTRY AND COMPUTATION. THE PROJECT WILL COMMENCE WITH 24-ATOM MACROCYCLES FOR WHICH A RICH EXPERIMENTAL DATA SET EXISTS. THESE MOLECULAR DOOR HINGES PRESENT TWO FLAT LEAVES CONNECTED WITH FLEXIBLE DOMAINS THAT SERVE AS THE HINGE PIN. THIS MODEL SYSTEM IS COMPELLING BASED ON EASE OF SYNTHESIS, DIVERSITY OF TARGETS, AND PREDICTABLE BEHAVIORS. THESE EFFORTS WILL DELIVER WORKFLOWS THAT YIELD (1) PKA VALUES, (2) CHEMICAL SHIFTS, (3) ENVIRONMENT-DEPENDENT CONFORMATIONAL ENSEMBLE SAMPLING, (4) EQUILIBRIUM POSITION ANALYSIS, AND (5) THE THERMODYNAMICS OF HINGE MOTION. FURTHERMORE, THE ENERGETIC BASES FOR QUANTITATIVE CYCLIZATION WILL BE PROBED. SUBSEQUENTLY, THIS WORK WILL BE ELABORATED TO ADDITIONAL RING SIZES, RANGING FROM 22-28 ATOMS. THIS AWARD REFLECTS NSF'S STATUTORY MISSION AND HAS BEEN DEEMED WORTHY OF SUPPORT THROUGH EVALUATION USING THE FOUNDATION'S INTELLECTUAL MERIT AND BROADER IMPACTS REVIEW CRITERIA.- SUBAWARDS ARE NOT PLANNED FOR THIS AWARD.
assistance · Last action 2025-08-26
$300,000
Department of Education
TCU STUDENT SUPPORT SERVICES STEM PROJECT
assistance · Last action 2025-07-03
$272,364
National Science Foundation
REU SITE: PHYSICS AND ASTROPHYSICS AT TCU -THIS RESEARCH EXPERIENCES FOR UNDERGRADUATES (REU) SITE AT TEXAS CHRISTIAN UNIVERSITY PROVIDES EIGHT UNDERGRADUATE STUDENTS THE OPPORTUNITY TO PARTICIPATE IN NINE WEEKS OF RESEARCH ON TOPICS IN ATOMIC, MOLECULAR, BIOLOGICAL, AND CHEMICAL PHYSICS, AS WELL AS ASTRONOMY AND PLANETARY SCIENCE. THE MAIN GOAL OF THE PROGRAM IS TO PROVIDE A MEMORABLE AND POTENTIALLY CAREER-DEFINING EXPERIENCE FOR STUDENT PARTICIPANTS, WHO MAY NOT HAVE A CLEAR DIRECTION OF CAREER PATH UPON ENTERING THE PROGRAM. THOUGHTFULLY-SELECTED FIELD TRIPS, WEEKLY DISCUSSIONS WITH OTHER STUDENTS AND FACULTY, AND WORKSHOPS ON CAREER-PLANNING ARE VITAL COMPONENTS OF THE REU PROGRAM, PROVIDING OPPORTUNITIES FOR STUDENTS TO CONSIDER A BROAD RANGE OF CAREER POSSIBILITIES AND PROFESSIONS IN PHYSICS AND ENGINEERING-RELATED FIELDS EXTENDING BEYOND THE FOCUSED SUMMER RESEARCH PROJECT. IN ADDITION TO PARTICIPATING IN RESEARCH WITH AN EXPERIENCED MENTOR, THE REU STUDENTS WILL ENGAGE IN WEEKLY ACTIVITIES TO ENSURE NOT ONLY THAT THEIR RESEARCH STAYS ON TRACK BUT THAT THEY HAVE AN ENGAGING COLLEGIAL AND SCHOLARLY EXPERIENCE. THE SUMMER EXPERIENCE CULMINATES WITH A FINAL ORAL RESEARCH PRESENTATION GIVEN BY PARTICIPANTS TO TCU UNDERGRADUATE AND GRADUATE STUDENTS AND FACULTY. THIS AWARD IS SUPPORTED BY THE DIVISION OF PHYSICS AND THE DIVISION OF ASTRONOMICAL SCIENCES WITHIN NSF'S MATHEMATICAL AND PHYSICAL SCIENCES DIRECTORATE. THIS AWARD REFLECTS NSF'S STATUTORY MISSION AND HAS BEEN DEEMED WORTHY OF SUPPORT THROUGH EVALUATION USING THE FOUNDATION'S INTELLECTUAL MERIT AND BROADER IMPACTS REVIEW CRITERIA.
assistance · Last action 2024-05-07
$271,483
National Science Foundation
GRADUATE RESEARCH FELLOWSHIP PROGRAM (GRFP) -THE NATIONAL SCIENCE FOUNDATION (NSF) GRADUATE RESEARCH FELLOWSHIP PROGRAM (GRFP) IS A HIGHLY COMPETITIVE, FEDERAL FELLOWSHIP PROGRAM. GRFP HELPS ENSURE THE VITALITY AND DIVERSITY OF THE SCIENTIFIC AND ENGINEERING WORKFORCE OF THE UNITED STATES. THE PROGRAM RECOGNIZES AND SUPPORTS OUTSTANDING GRADUATE STUDENTS WHO ARE PURSUING RESEARCH-BASED MASTER'S AND DOCTORAL DEGREES IN SCIENCE, TECHNOLOGY, ENGINEERING, AND MATHEMATICS (STEM) AND IN STEM EDUCATION. THE GRFP PROVIDES THREE YEARS OF FINANCIAL SUPPORT FOR THE GRADUATE EDUCATION OF INDIVIDUALS WHO HAVE DEMONSTRATED THEIR POTENTIAL FOR SIGNIFICANT RESEARCH ACHIEVEMENTS IN STEM AND STEM EDUCATION. THIS AWARD SUPPORTS THE NSF GRADUATE FELLOWS PURSUING GRADUATE EDUCATION AT THIS GRFP INSTITUTION. THIS AWARD REFLECTS NSF'S STATUTORY MISSION AND HAS BEEN DEEMED WORTHY OF SUPPORT THROUGH EVALUATION USING THE FOUNDATION'S INTELLECTUAL MERIT AND BROADER IMPACTS REVIEW CRITERIA.
assistance · Last action 2025-08-06
$261,000
National Science Foundation
COLLABORATIVE RESEARCH: UNRAVELING THE EVOLVING DYNAMICS OF STAR CLUSTERS USING MILKY WAY-LIKE GALAXY SIMULATIONS -STAR CLUSTERS ARE DENSE COLLECTIONS OF HUNDREDS TO HUNDREDS OF THOUSANDS OF STARS. THESE STAR CLUSTERS ARE FOUND AROUND MOST GALAXIES IN THE UNIVERSE. THIS RESEARCH TEAM WILL STUDY HOW THESE STAR CLUSTERS EVOLVE AND INTERACT WITH THEIR HOST GALAXY. THE INVESTIGATORS WILL ANALYZE ADVANCED COMPUTER SIMULATIONS THAT TRACE THE ORIGIN AND EVOLUTION OF GALAXIES LIKE THE MILKY WAY AND THEIR STAR CLUSTERS. THEY WILL CREATE PLANETARIUM SHOWS AND OTHER OUTREACH PROGRAMS ACCESSIBLE TO EVERYONE IN THE STATES OF CALIFORNIA AND TEXAS. THIS PROGRAM WILL PROVIDE RESEARCH OPPORTUNITIES AND TRAINING IN CODING AND NUMERICAL SIMULATIONS FOR UNDERGRADUATE AND GRADUATE STUDENTS IN ASTROPHYSICS. THE RESEARCH TEAM WILL USE HIGH-RESOLUTION COSMOLOGICAL SIMULATIONS TO TRACK THE ORBITAL DYNAMICS OF LONG-LASTING OPEN STAR CLUSTERS ACROSS TIME AND SPACE. THEY WILL EXAMINE HOW AN EVOLVING POTENTIAL AND GALACTIC ENVIRONMENT IMPACT THE ORBITAL TRAJECTORY OF STAR CLUSTERS. THEY WILL ALSO ASSESS THE RELIABILITY OF TRADITIONAL ORBIT MODELING TECHNIQUES, SPECIFICALLY ORBIT INTEGRATION USING A FIXED POTENTIAL, TO ACCURATELY TRACE THE LOCATION AND HISTORY OF STELLAR SYSTEMS OLDER THAN 1 GYR. THIS RESEARCH WILL GENERATE A COMPREHENSIVE MULTI-SCALE PERSPECTIVE INTO THE RELATIONSHIP BETWEEN STAR CLUSTER DYNAMICS AND THE EVOLVING GALACTIC POTENTIAL. THIS AWARD REFLECTS NSF'S STATUTORY MISSION AND HAS BEEN DEEMED WORTHY OF SUPPORT THROUGH EVALUATION USING THE FOUNDATION'S INTELLECTUAL MERIT AND BROADER IMPACTS REVIEW CRITERIA.- SUBAWARDS ARE NOT PLANNED FOR THIS AWARD.
assistance · Last action 2025-08-14
$241,527
National Science Foundation
TOPOLOGICAL INVARIANTS AND THE CLASSIFICATION OF NUCLEAR C*-ALGEBRAS -THIS PROJECT EXPLORES HOW TOPOLOGICAL FEATURES?CAPTURED THROUGH COMPUTABLE INVARIANTS AND CLASSIFICATION SCHEMES?HELP ORGANIZE COMPLEX MATHEMATICAL STRUCTURES KNOWN AS OPERATOR ALGEBRAS. OPERATOR ALGEBRAS ORIGINALLY SERVED AS A ROBUST MATHEMATICAL FRAMEWORK DEVELOPED BY VON NEUMANN AND OTHERS TO MODEL HEISENBERG'S APPROACH TO QUANTUM MECHANICS, AND THEIR STUDY IS A VITAL PART OF MODERN ANALYSIS. ENDURING INTEREST IN THIS AREA OF RESEARCH CENTERS LARGELY ON ITS MANY CONNECTIONS AND APPLICATIONS TO OTHER MATHEMATICAL AND SCIENTIFIC FIELDS. OPERATOR ALGEBRAS CAN BE CONSTRUCTED FROM, AND IN SOME CASES ENCODE, MANY IMPORTANT MATHEMATICAL STRUCTURES SUCH AS SYMMETRIES, TIME-EVOLVING SYSTEMS, GRAPHS, AND NUMBER FIELDS. THEY ALSO PLAY A SIGNIFICANT ROLE IN AREAS LIKE QUANTUM COMPUTING AND CONDENSED-MATTER PHYSICS. A PRIMARY FOCUS OF THIS PROJECT IS ON DISCERNING THE FINE STRUCTURE OF INFINITE-DIMENSIONAL OPERATOR ALGEBRAS THROUGH APPROXIMATIONS BY SIMPLER, FINITE-DIMENSIONAL MODELS. THE PROJECT INVOLVES MENTORING OF EARLY-CAREER RESEARCHERS AND STUDENTS THROUGH GUIDED INVESTIGATIONS AND COLLABORATIVE LEARNING EXPERIENCES. THE RESEARCH FOCUSES ON ONE OF THE MOST IMPORTANT RECENT RESULTS IN OPERATOR ALGEBRAS, NAMELY THE CLASSIFICATION OF SIMPLE AMENABLE C*-ALGEBRAS OF FINITE NON-COMMUTATIVE COVERING DIMENSION. CONNES' FIELDS MEDAL-WINNING WORK ON THE STRUCTURE AND CLASSIFICATION OF AMENABLE VON NEUMANN ALGEBRAS IN THE 1970S REMAINS FUNDAMENTAL TO MODERN VON NEUMANN ALGEBRA THEORY, AND IN THE TOPOLOGICAL SETTING OF C*-ALGEBRAS, THE ELLIOTT CLASSIFICATION PROGRAM WAS INITIATED IN THE 1990S SEEKING ANALOGOUS RESULTS FOR SIMPLE AMENABLE C*-ALGEBRAS. THIS LARGE-SCALE, WORLDWIDE ENDEAVOR RECENTLY CULMINATED IN THE COMPLETE CLASSIFICATION OF SEPARABLE, SIMPLE, NUCLEAR, Z-STABLE C*-ALGEBRAS IN THE UCT CLASS. THIS PROJECT INVOLVES FAR-REACHING GENERALIZATIONS OF SUCH RESULTS, WITH APPLICATIONS BEYOND THE CLASSIFICATION PROGRAM. THIS AWARD REFLECTS NSF'S STATUTORY MISSION AND HAS BEEN DEEMED WORTHY OF SUPPORT THROUGH EVALUATION USING THE FOUNDATION'S INTELLECTUAL MERIT AND BROADER IMPACTS REVIEW CRITERIA.- SUBAWARDS ARE NOT PLANNED FOR THIS AWARD.
assistance · Last action 2025-07-28
$232,818
Department of Health and Human Services
EXAMINING PATHWAYS OF CONNECTION TO EDUCATION, TRAINING, AND EMPLOYMENT AMONG EMERGING ADULTS EXPERIENCING LOW-INCOMES AND THE IMPACT ON LATER HEALTH AND ECONOMIC WELL-BEING
assistance · Last action 2025-08-26
$199,484
National Science Foundation
CRII: III: LEARNING SPATIOTEMPORAL IMPACTS OF TEXT-ENRICHED TRAFFIC EVENTS WITH INJECTION OF INTERPRETABILITY FROM GRAPH NEURAL NETWORKS AND PHYSICS-INFORMED MACHINE LEARNING -PREDICTING THE FUTURE SPATIOTEMPORAL IMPACTS AND UNDERLYING CASCADING PATTERNS OF THE TRAFFIC INCIDENTS THAT OCCUR WITHIN THE TRANSPORTATION SYSTEMS COULD OFFER CONSIDERABLE BENEFITS TO SOCIETY. AS TRAFFIC INCIDENTS ARE RESPONSIBLE FOR APPROXIMATELY 25% OF ALL TRAFFIC DELAYS, COSTING THE UNITED STATES ECONOMY AN ESTIMATED $87 BILLION ANNUALLY, AN ACCURATE AND EXPLAINABLE PREDICTIVE SOLUTION CAN HELP MITIGATE THESE DEVASTATING SPATIOTEMPORAL IMPACTS BY ENABLING QUICKER RESPONSE TIMES FROM EMERGENCY SERVICES, MORE EFFECTIVE TRAFFIC MANAGEMENT, AND BETTER PUBLIC ADVISORIES. ADVANCED ANALYTICS AND MACHINE LEARNING ALGORITHMS CAN ANALYZE REAL-WORLD DATA TO FORECAST THE SEVERITY AND DURATION OF SPATIOTEMPORAL EVENTS THAT OCCURRED WITHIN THE CYBER-PHYSICAL-SOCIAL SYSTEMS, THEREBY AIDING IN THE ALLOCATION OF RESOURCES AND REDUCING BOTH HUMAN AND ECONOMIC LOSSES. THE PRIMARY INNOVATION OF THIS PROJECT WILL BE ITS ABILITY TO LEARN THE COMPLEX RELATIONSHIP BETWEEN TRAFFIC INCIDENTS AND HOW THEIR IMPACT WILL CASCADE AMONG THE GEOMETRIC STRUCTURE OF TRANSPORTATION SYSTEMS AND EXTRACT UNDERSTANDABLE RULES AND PATTERNS FOR DECISION-MAKERS. THE OBJECTIVE OF THIS PROJECT IS TO GATHER AND ANALYZE EXTENSIVE TRAFFIC DATA FROM VARIOUS HETEROGENEOUS PLATFORMS TO LEARN MORE REPRESENTATIVE EMBEDDINGS OF TRAFFIC INCIDENTS. THE GOAL IS TO CREATE A RANGE OF INTERPRETABLE GRAPH MINING AND MACHINE LEARNING TECHNIQUES THAT CAN ENHANCE UNDERSTANDING OF THE CASCADING IMPACTS NOT ONLY IN TRANSPORTATION SYSTEMS BUT ALSO ACROSS HETEROGENOUS CYBER-PHYSICAL-SOCIAL SYSTEMS. THIS PROJECT WILL DEVELOP 1) A NOVEL MULTIMODAL REPRESENTATION LEARNING APPROACH COMBINING MACHINE LEARNING AND GRAPH MINING TO LEARN THE TEXT-ENRICHED EMBEDDING OF THE TRAFFIC EVENTS FROM HETEROGENOUS SOCIAL/NEWS MEDIA AND TRANSPORTATION NETWORKS, 2) NOVEL SPATIOTEMPORAL DATA MINING AND TRANSFORMER-BASED GRAPH NEURAL NETWORK METHODS TO DETECT TRANSPORTATION EVENTS AND THEIR CASCADING IMPACTS ON HETEROGENEOUS TRANSPORTATION NETWORKS, 3) A NEW PHYSICS-INFORMED MACHINE LEARNING SOLUTION TO MODEL THE CASCADING IMPACTS WITH THE KORTEWEG-DE VRIES (KDV) EQUATION AND INJECT MODEL INTERPRETABILITY WHILE FORECASTING THE TRAFFIC EVENTS IN SPECIFIC SCENARIOS. THE PROPOSED PHYSICS-INFORMED MACHINE LEARNING SOLUTIONS COULD DECOUPLE THE MODEL'S DEPENDENCIES ON LARGE DATASETS SO THAT THE TRANSPORTATION SYSTEMS IN LESS REPRESENTED/RURAL AREAS COULD SWIFTLY INFER ACCURATE FUTURE STATUSES WHEN FAILURE HAPPENS. THESE ADVANCEMENTS WILL MAKE SIGNIFICANT CONTRIBUTIONS TO THE FIELDS OF EXPLAINABLE GRAPH MINING, PHYSICS-INFORMED MACHINE LEARNING, AND SPATIOTEMPORAL EVENT ANALYSIS. THE EXPECTED OUTCOMES WILL ENRICH THE UNDERSTANDING OF THE NATURE OF TRAFFIC EVENTS IN COMPLEX TRANSPORTATION NETWORKS. THIS AWARD REFLECTS NSF'S STATUTORY MISSION AND HAS BEEN DEEMED WORTHY OF SUPPORT THROUGH EVALUATION USING THE FOUNDATION'S INTELLECTUAL MERIT AND BROADER IMPACTS REVIEW CRITERIA.- SUBAWARDS ARE NOT PLANNED FOR THIS AWARD.
assistance · Last action 2025-09-16
$168,912
National Science Foundation
COLLABORATIVE RESEARCH: PHOTOELECTROSYNTHETIC AMINOXYL CATALYZED ALCOHOL OXIDATION -LIGNOCELLULOSIC BIOMASS OFFERS A CARBON-NEUTRAL ALTERNATIVE SOURCE OF FUELS AND CHEMICALS WHICH ARE CURRENTLY SOURCED FROM PETROLEUM AND OTHER FOSSIL FUELS. CONVERTING LIGNIN, A LARGELY UNDERUTILIZED YET CHEMICALLY RICH BYPRODUCT OF THE BIOREFINING INDUSTRY, TO VALUABLE AROMATIC PLATFORM CHEMICALS IS AN ENERGY-INTENSIVE PROCESS THAT HAS MADE THIS APPROACH COST PROHIBITIVE. RECENTLY, DYE-SENSITIZED PHOTOELECTROSYNTHETIC CELLS (SIMILAR TO PHOTOVOLTAIC CELLS) HAVE EMERGED AS A LOW-COST AND ENVIRONMENTALLY FRIENDLY TECHNOLOGY FOR CONVERTING SOLAR ENERGY INTO CHEMICAL FUELS OR ELECTRICITY. THESE PHOTOELECTROCHEMICAL CELLS OFFER A MEANS OF USING RENEWABLE SOLAR ENERGY TO DRIVE ENERGY-INTENSIVE CHEMICAL CONVERSIONS AT AMBIENT TEMPERATURE AND PRESSURE. HERE, THE COLLABORATIVE FUNDAMENTAL RESEARCH PROJECT WILL STUDY HOW A DYE-SENSITIZED PHOTOANODE CAN CHEMOSELECTIVELY OXIDIZE LIGNIN WITH A SUITABLE CATALYST AS A FIRST STEP TOWARD A COMPLETE LIGHT-DRIVEN LIGNIN DEPOLYMERIZATION PROCESS. THIS APPROACH WILL EXPAND ON THE USE OF HETEROGENEOUS CATALYSIS FOR THE OXIDATION OF PRIMARY AND SECONDARY ALCOHOLS TO PRODUCE CARBONYL OR CARBOXYL COMPOUNDS FOR THE FINE CHEMICAL AND PHARMACEUTICAL INDUSTRIES. THIS WORK REPRESENTS A NEW APPLICATION FOR DYE-SENSITIZED PHOTOELECTROSYNTHETIC CELLS, AND THE RESEARCH FINDINGS FROM THE PROJECT WILL BE DISSEMINATED TO THE PUBLIC THROUGH RESEARCH PUBLICATIONS, CONFERENCE PRESENTATIONS, AND BY ORGANIZING AND HOSTING EDUCATIONAL OUTREACH PROGRAMS FOR FUTURE PROFESSIONALS IN THE STEM FIELD. THE PIS WILL ALSO ACTIVELY RECRUIT AND SUPPORT UNDERREPRESENTED MINORITY STUDENTS THROUGH THE OUTREACH PROGRAM. ORGANIC OXIDATION REACTIONS ARE IMPORTANT IN ORGANIC SYNTHESIS OR LIGNOCELLULOSIC BIOMASS PROCESSING. CHEMOSELECTIVE OXIDATION OF THE ALIPHATIC AND/OR BENZYLIC ALCOHOL MOIETIES IN LIGNIN IS A GOOD TARGET FOR CONTROLLING THE DEGRADATION OF LIGNIN TO GENERATE DESIRED SMALL MOLECULAR PRODUCTS. THIS PROJECT AIMS TO ELUCIDATE A PHOTOELECTROSYNTHETIC CHEMOSELECTIVE OXIDATION OF ALCOHOL MOIETIES IN LIGNIN BY COMBINING THE USE OF AMINOXYL MEDIATORS WITH A DYE-SENSITIZED PHOTOANODE (DSP) AT ROOM TEMPERATURE. ESSENTIAL TO THIS APPROACH IS THE USE OF A DYE-SENSITIZED ELECTRODE INTERFACE TO ACTIVATE A NITROXYL MEDIATOR VIA LIGHT-INDUCED CHARGE SEPARATION. THIS PRESENTS BOTH A NEW APPROACH FOR DRIVING THE PHOTOCHEMICAL OXIDATION OF THE SECONDARY BENZYLIC ALCOHOL AND THE PRIMARY ALIPHATIC ALCOHOL FUNCTIONAL GROUPS FOUND IN LIGNIN, AS WELL AS A NEW PHOTOCATALYTIC APPLICATION FOR DYE-SENSITIZED PHOTOELECTROSYNTHETIC CELLS, WHICH HAVE TRADITIONALLY FOCUSED ON SOLAR WATER SPLITTING. THE APPROACH WILL INVOLVE (1) THE SYNTHESIS OF PHOTOACTIVE POLYMERIC CATALYSTS AND THE ELUCIDATION OF THEIR UNDERLYING PHOTOCHEMICAL ELECTRON TRANSFER PROPERTIES FOR ACTIVATING NITROXYL MEDIATORS, (2) THE FABRICATION AND EVALUATION OF MESOPOROUS SEMICONDUCTOR-BASED ELECTRODES SPECIFICALLY DESIGNED FOR THE CHEMOSELECTIVE OXIDATION OF LIGNIN DIMER MODEL COMPOUNDS WITH A SERIES OF NITROXYL MEDIATORS, AND (3) THE ELUCIDATION OF MECHANISTIC PATHWAYS FOR THE LIGHT-DRIVEN OXIDATION OF 2O BENZYLIC AND 1O ALIPHATIC ALCOHOLS USING A DSP AND ADDRESS PRACTICAL CHALLENGES PRESENTED BY THE USE OF OLIGOMER MODEL COMPOUNDS AND TECHNICAL LIGNIN. THIS RESEARCH IS SIGNIFICANT AS A FIRST TEST CASE OF A DSP TO CARRY OUT THE SELECTIVE OXIDATION OF REAL LIGNIN AT ROOM TEMPERATURE AS A FIRST STEP TOWARD LIGHT-DRIVEN BIOMASS CONVERSION TO VALUE-ADDED CHEMICALS. THIS AWARD REFLECTS NSF'S STATUTORY MISSION AND HAS BEEN DEEMED WORTHY OF SUPPORT THROUGH EVALUATION USING THE FOUNDATION'S INTELLECTUAL MERIT AND BROADER IMPACTS REVIEW CRITERIA.
assistance · Last action 2023-05-30
$124,566
Department of Agriculture
** AWARDS ISSUED PRIOR TO JANUARY 20, 2025, WERE FUNDED UNDER PREVIOUS ADMINISTRATIONS AND MAY NOT REFLECT THE PRIORITIES AND POLICIES OF THE CURRENT ADMINISTRATION.** POLLINATION IS VITAL FOR FOOD PRODUCTION, YET KEY POLLINATORS, INCLUDING BUMBLEBEES, ARE DECLINING AT ALARMING RATES. TO STOP THESE DECLINES, WE MUST FIND WAYS TO BOLSTER BUMBLEBEE HEALTH. ONE PROMISING APPROACH IS TO IMPROVE GUT MICROBIOME FUNCTIONALITY USING PROBIOTICS. THE BUMBLEBEE GUT MICROBIOME INCLUDES FIVE UBIQUITOUS CORE BACTERIAL SPECIES AND VARIABLE MIXTURES OF NONCORE SPECIES. COMPOSITION OF THESE BACTERIAL SPECIES, AND STRAINS WITHIN THEM, VARIES EXTENSIVELY AMONG BUMBLEBEES. YET HOW THIS VARIATION IMPACTS HOST FUNCTION--AND WHETHER IT CAN BE LEVERAGED TO SUPPORT BUMBLEBEE HEALTH--ARE UNKNOWN. THE PROPOSED RESEARCH AIMS TO DEVELOP NATIVE PROBIOTICS TO PROMOTE THE HEALTH AND POLLINATION SERVICES OF MANAGED BUMBLEBEES. THIS ADDRESSES THE AFRI PRIORITY AREA PLANT HEALTH AND PRODUCTION AND PLANT PRODUCTS, BY DEVELOPING A NEW APPROACH TO MAINTAIN POLLINATOR HEALTH IN THE FACE OF ENVIRONMENTAL CHANGE (PROGRAM AREA POLLINATOR HEALTH: RESEARCHAND APPLICATION; A1113). WE WILL DESIGN PROBIOTICS AND OPTIMIZE THEIR DELIVERY TO BEES, WHILE EVALUATING THE POTENTIAL IMPLICATIONS FOR CONSERVATION IF PROBIOTICS CAN BE TRANSMITTED AMONG COLONIES OR SPECIES IN THE ENVIRONMENT. TO DO SO, WE WILL USE TOOLS AND CONCEPTS FROM MICROBIAL ECOLOGY, BIODIVERSITY-ECOSYSTEM FUNCTION THEORY, AND METAGENOMICS. THIS RESEARCH WILL IMPROVE UNDERSTANDING OF HOW MICROBES SHAPE THE HEALTH OF A CRITICAL GROUP OF POLLINATORS AND PAVE THE WAY FOR ECOLOGICALLY INFORMED DESIGN OF FUTURE PROBIOTICS, IN BOTH BEES AND OTHER HOST ORGANISMS. BY FORTIFYING THE HEALTH OF KEY POLLINATORS AND LIMITING THEIR POPULATION DECLINES, THE U.S. WILL BE BETTER ABLE TO PROTECT FOOD PRODUCTION IN THE FUTURE.
assistance · Last action 2026-04-06
$87,519
National Science Foundation
CONFERENCE: CBMS CONFERENCE: CLASSIFYING AMENABLE OPERATOR ALGEBRAS -THE DEPARTMENT OF MATHEMATICS OF TEXAS CHRISTIAN UNIVERSITY WILL HOST AN NSF/CBMS (CONFERENCE BOARD OF THE MATHEMATICAL SCIENCES) REGIONAL CONFERENCE IN THE MATHEMATICAL SCIENCES TITLED CLASSIFYING AMENABLE OPERATOR ALGEBRAS, WHICH WILL TAKE PLACE ON ITS CAMPUS IN FORT WORTH, TEXAS, FROM JUNE 9, 2025 TO JUNE 13, 2025. THE PRINCIPAL LECTURER WILL BE CHRISTOPHER SCHAFHAUSER FROM THE UNIVERSITY OF NEBRASKA-LINCOLN. THE MEETING WILL SERVE TO TRAIN WORKING MATHEMATICIANS AND GRADUATE STUDENTS ALIKE IN RECENT DEVELOPMENTS AND NEW TECHNIQUES THAT HAVE ALLOWED PROGRESS IN THE FIELD OF OPERATOR ALGEBRAS AND THEIR CLASSIFICATION. IN ADDITION TO PROFESSOR SCHAFHAUSER'S MAIN LECTURES THERE WILL BE FIVE COMPLEMENTARY FOLLOW-UP TALKS BY ADDITIONAL SPEAKERS. THE PROGRAM WILL ALSO INCLUDE OTHER ACTIVITIES DESIGNED TO BROADEN PARTICIPATION AND TO PROVIDE YOUNG RESEARCHERS IN THE FIELD OPPORTUNITIES TO BUILD PROFESSIONAL NETWORKS AND SHARE THEIR RESEARCH. IN MORE DETAIL, OPERATOR ALGEBRAS, INCLUDING C*-ALGEBRAS AND VON NEUMANN ALGEBRAS, ORIGINALLY AROSE FROM QUANTUM PHYSICS. ENDURING INTEREST IN THEM IS LARGELY DUE TO THE REALIZATION THAT THEY CAN BE CONSTRUCTED FROM, AND IN SOME CASES ENCODE, MANY OTHER STRUCTURES, SUCH AS SYMMETRIES, TIME-EVOLVING SYSTEMS, GRAPHS, AND NUMBER FIELDS. ALAIN CONNES' WORK ON THE STRUCTURE AND CLASSIFICATION OF AMENABLE VON NEUMANN ALGEBRAS IN THE 1970S REMAINS FUNDAMENTAL TO MODERN VON NEUMANN ALGEBRA THEORY. IN THE TOPOLOGICAL SETTING OF C*-ALGEBRAS, THE CLASSIFICATION PROGRAM FOR AMENABLE C*-ALGEBRAS WAS INITIATED IN THE 1990S, SEEKING ANALOGOUS RESULTS. THIS LARGE-SCALE WORLDWIDE ENDEAVOR RECENTLY CULMINATED IN THE PROOF OF THE MAIN CONJECTURE IN THE AREA, GIVING A COMPLETE CLASSIFICATION OF A BROAD CLASS OF SIMPLE AMENABLE C*-ALGEBRAS. THIS MAIN LECTURES WILL PROVIDE AN ACCESSIBLE INTRODUCTION TO THE CLASSIFICATION RESULT AND THE FOLLOW-UP TALKS WILL FOCUS ON APPLICATIONS. THE CONFERENCE WILL ALSO FEATURE A PANEL DISCUSSION ABOUT FUTURE RESEARCH DIRECTIONS. THE CONFERENCE WEBSITE MAY BE FOUND AT HTTPS://FACULTY.TCU.EDU/JCARRION/CBMS-2025.HTML. THIS AWARD REFLECTS NSF'S STATUTORY MISSION AND HAS BEEN DEEMED WORTHY OF SUPPORT THROUGH EVALUATION USING THE FOUNDATION'S INTELLECTUAL MERIT AND BROADER IMPACTS REVIEW CRITERIA.- SUBAWARDS ARE NOT PLANNED FOR THIS AWARD.
assistance · Last action 2024-12-19
$44,290
Department of Defense
TUITION AND FEES
contract · Last action 2024-09-04
$35,080
Department of Defense
TUITION AND FEES
contract · Last action 2025-07-22
$34,716
Department of Defense
TUITION AND FEES
contract · Last action 2025-07-08
$34,309
Department of Defense
TUITION AND FEES
contract · Last action 2025-07-08
$31,516
Department of Defense
TUITION AND FEES
contract · Last action 2025-05-22
$31,516
Department of Defense
TUITION AND FEES
contract · Last action 2021-11-18
$31,241
Department of Defense
TUITION AND FEES
contract · Last action 2021-07-27
$31,241
Department of Defense
TUITION AND FEES
contract · Last action 2021-05-06
$30,159
Department of Defense
TUITION AND FEES
contract · Last action 2021-01-15
$30,159
Department of Defense
TUITION AND FEES TX, TEXAS CHRISTIAN UNIVERSITY
contract · Last action 2026-03-18
$29,800
Department of Agriculture
COURSE INSTRUCTOR TO DELIVER WORKING EFFECTIVELY WITH LIVESTOCK PRODUCERS JUNE 7 THRU 18, 2010 (30 STUDENTS); TO INCLUDE ALL INSTRUCTIONAL AND SUPPORT STAFF, TRAINING MATERIALS, EQUIPMENT, AND FACILITIES THAT MEET TRAINING OBJECTIVES.
contract · Last action 2010-02-24
$22,500
Department of Defense
IGF::OT::IGF HYDRILLA SAMPLING U433F20
contract · Last action 2015-12-11
$17,082

Federal contract dollars to this establishment. Primary NAICS: 541990 - ALL OTHER PROFESSIONAL, SCIENTIFIC, AND TECHNICAL SERVICES. Last action: 2026-03-18. Source: USAspending.gov, net obligations. Recipient address is the SAM registration / HQ address, not necessarily the worksite.

Inspection history

Date	Trigger	Violations	Serious	Penalty
1993-10-29	Complaint	3	2	$1,950
1989-09-12	Complaint	0	—	$0

Source: OSHA IMIS. Citation amounts reflect initially assessed penalties; final amounts after appeal may differ.

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