OCCIDENTAL COLLEGE

OCCIDENTAL COLLEGE UPWARD BOUND GRANT PROPOSAL 2022

GRANT PROGRAM

CREATING OPPORTUNITIES FOR HIGH-ACHIEVING STUDENTS IN SCIENCE AND MATHEMATICS THROUGH SCHOLARSHIPS, RESEARCH EXPERIENCES, LEADERSHIP, AND COMMUNITY

CENTER FOR UNDERGRADUATE RESEARCH IN MATHEMATICS -THE CENTER FOR UNDERGRADUATE RESEARCH IN MATHEMATICS (CURM) PROVIDES FUNDING AND TRAINING FOR UNDERGRADUATE RESEARCH COURSES DURING THE ACADEMIC YEAR THAT ARE CARRIED OUT IN COLLABORATION BETWEEN A TWO-YEAR OR COMMUNITY COLLEGE AND A BACHELOR'S-GRANTING INSTITUTION. FACULTY MEMBERS FUNDED BY CURM RECEIVE TRAINING IN INCLUSIVE AND SCAFFOLDED RESEARCH MENTORING FOR EARLY-CAREER STUDENTS, FUNDING TO SUPPORT RESEARCH ACTIVITIES AND COLLABORATION DURING THE ACADEMIC YEAR, AND MODELS FOR INSTITUTIONALIZING ACADEMIC YEAR UNDERGRADUATE RESEARCH. CURM ALSO PROVIDES MENTORSHIP FOR DEVELOPING A STRONG PROPOSAL TO CURM FOR FACULTY WITH LESS EXPERIENCE IN GRANT WRITING. INTELLECTUAL MERITS INCLUDE CONTRIBUTIONS TO RESEARCH, PRESENTATIONS AT CONFERENCES AND WORKSHOPS, AND PUBLISHING RESEARCH PAPERS IN MULTIPLE SUBFIELDS OF MATHEMATICS. BROADER IMPACTS INCLUDE EARLY EXPOSURE FOR STUDENTS TO THE HIGH IMPACT PRACTICE OF RESEARCH, INCREASING TRANSFER RATES FOR TWO YEAR AND COMMUNITY COLLEGE STUDENTS, AND DEVELOPMENT OF STRONG RESEARCH AND RESEARCH MENTORING SKILLS IN MATHEMATICS FACULTY ACROSS THE US. CURM ADDRESSES PREVIOUSLY IDENTIFIED BARRIERS TO UNDERGRADUATE RESEARCH AT 2-YEAR AND COMMUNITY COLLEGES. PROVIDING FUNDING FOR FACULTY HELPS ADDRESS HIGH TEACHING LOADS AND LACK OF TRAVEL FUNDING. CREDIT-BEARING COURSE-BASED RESEARCH OPPORTUNITIES HELP ADDRESS LACK OF STUDENT AWARENESS OF RESEARCH OPPORTUNITIES, AND ALSO STUDENT WORKLOAD ISSUES. INTER-INSTITUTIONAL COMMUNITIES OF PRACTICE HELP ADDRESS LACK OF STUDENT AWARENESS, LACK OF SENSE OF BELONGING AT 4-YEAR INSTITUTIONS FOR 2-YEAR COLLEGE STUDENTS, AND THE SHORT TIME STUDENTS MAY BE ENROLLED AT 2-YEAR COLLEGES. FINALLY, TRAINING FOR FACULTY IN RESEARCH AREAS WITH RICH SELECTIONS OF RESEARCH PROJECTS FOR EARLY CAREER STUDENTS HELPS ADDRESS FACULTY UNCERTAINTY ABOUT HOW TO FIND AND EFFECTIVELY MENTOR AN APPROPRIATE RESEARCH PROJECT. WE WILL OFFER A RESEARCH IMMERSION EXPERIENCE FOR FACULTY IN THOSE RESEARCH AREAS, INCLUDING DATA SCIENCE, GRAPH THEORY, MATHEMATICAL MODELING, AND MATHEMATICS EDUCATION. DOING SO WILL ALSO INCREASE THE RESEARCH EXPERTISE IN PARTICIPATING INSTITUTIONS. THIS AWARD REFLECTS NSF'S STATUTORY MISSION AND HAS BEEN DEEMED WORTHY OF SUPPORT THROUGH EVALUATION USING THE FOUNDATION'S INTELLECTUAL MERIT AND BROADER IMPACTS REVIEW CRITERIA.- SUBAWARDS ARE PLANNED FOR THIS AWARD.

CAREER: INTEGRATING UNDERGRADUATE RESEARCH, CITIZEN SCIENCE, AND MUSEUM GENOMICS TO EXPLORE A CENTURY OF CHANGE IN NORTH AMERICAN BIRDS

PHOTOCATALYZED AND ENANTIOSELECTIVE UMPOLUNG C-C BOND FORMING REACTIONS OF CARBONYLS

EQUIPMENT: MRI: TRACK 1 AN INTERDISCIPLINARY APPROACH TO HIGH-RESOLUTION SEA AND LAKE-FLOOR MAPPING THROUGH ACQUISITION OF AN R2SONIC 2024 MULTIBEAM SONAR -THIS AWARD IS MADE TO OCCIDENTAL COLLEGE TO PURCHASE AN ULTRA-HIGH-RESOLUTION MULTIBEAM SONAR TO COLLECT BATHYMETRIC DATA, INCLUDING MULTISPECTRAL ACOUSTIC BACKSCATTER, IN OCEANS AND LAKES UP TO 500M IN DEPTH. THIS SYSTEM WILL SUPPORT ONGOING FACULTY AND UNDERGRADUATE RESEARCH PROJECTS AND DEVELOP UPPER-DIVISION COURSE CURRICULUM AT OCCIDENTAL COLLEGE, A PRIMARILY UNDERGRADUATE-SERVING INSTITUTION. FACULTY AND STUDENT RESEARCH THAT WILL BE ENABLED BY THIS AWARD WILL ADDRESS A WIDE RANGE OF ENVIRONMENTAL SCIENCE RESEARCH QUESTIONS AROUND THE GLOBE. FOR EXAMPLE, THE MULTIBEAM SONAR WILL BE USED TO MAP EARTHQUAKE-GENERATED SLOPE-FAILURE DEPOSITS IN LAKES IN THE TETON RANGE IN WYOMING, DETERMINE THE BIOTIC BENTHIC COMPOSITION OF CORAL REEFS IN JAMAICA, AND ASSESS THE SUCCESS OF A NEWLY-CONSTRUCTED RESTORATION REEF IN SOUTHERN CALIFORNIA. UNDER THE MENTORSHIP OF BIOLOGY AND GEOLOGY FACULTY, OCCIDENTAL UNDERGRADUATE STUDENTS WILL GAIN VALUABLE EXPERIENCE WORKING WITH THIS MULTIBEAM SONAR SYSTEM, MANAGING AND MANIPULATING LARGE DATA SETS, AND ASSOCIATED MODELING, WHICH ARE KEY TO THEIR SUCCESS IN POST-GRADUATE CAREERS IN STEM FIELDS. A MAJOR GOAL OF THIS PROJECT IS TO DETERMINE A CLEAR PLAN TO ACQUIRE, MAINTAIN, AND DEPOSIT DATA INTO AN APPROPRIATE DISCIPLINARY ARCHIVE TO ENSURE THAT BEST PRACTICES FOR LONG-TERM DATA STEWARDSHIP AND INTEGRATION ARE MET. THIS INCLUDES MAKING HIGH-RESOLUTION, HIGH QUALITY BATHYMETRIC DATA AND METADATA FREELY AVAILABLE TO THE PUBLIC. DATA PRODUCTS WILL BE MADE PUBLICLY ACCESSIBLE THROUGH SUBMISSION TO INTERNATIONALLY-RECOGNIZED DATA REPOSITORIES TO SERVE A BROAD RESEARCH COMMUNITY. THESE DATA PRODUCTS WILL NOT ONLY PROVIDE DATA-RICH BATHYMETRIC MAPS OF LOCATIONS WITHIN CALIFORNIA, WYOMING, JAMAICA AND BEYOND, BUT ALSO A SNAPSHOT IN TIME OF THE GEOPHYSICAL AND ECOLOGICAL STATUS OF THAT PARTICULAR LOCATION. IN ADDITION TO THE PHYSICAL EQUIPMENT, THIS AWARD WILL PROVIDE FUNDING FOR SOFTWARE LICENSES, IN-PERSON TRAINING, AND TIME FOR A RESEARCH ASSOCIATE WHO WILL DEPLOY, OPERATE, MAINTAIN, AND MANAGE THE SYSTEM AND ALL ASSOCIATED BATHYMETRIC DATA. THE RESEARCH ASSOCIATE WILL ALSO PROVIDE TECHNICAL SUPPORT AND CREATE TRAINING MATERIALS, FACILITATING THE LONG-TERM USE OF THE SYSTEM BY OCCIDENTAL AND THE BROADER RESEARCH COMMUNITY. THIS AWARD REFLECTS NSF'S STATUTORY MISSION AND HAS BEEN DEEMED WORTHY OF SUPPORT THROUGH EVALUATION USING THE FOUNDATION'S INTELLECTUAL MERIT AND BROADER IMPACTS REVIEW CRITERIA.- SUBAWARDS ARE NOT PLANNED FOR THIS AWARD.

MACROPHAGE SECOND-LINE RESPONSES TO GROUP A STREPTOCCOCUS INFECTION - PROJECT SUMMARY THE RESURGENCE OF SEVERE INVASIVE GROUP A STREPTOCOCCUS (GAS) INFECTIONS IN THE PAST DECADE IS A MAJOR PUBLIC HEALTH CONCERN IN THE UNITED STATES, AND GAPS IN UNDERSTANDING THE RESILIENCE OF GAS TO THE IMMUNE RESPONSE HAS IMPEDED THE DEVELOPMENT OF A MUCH-NEEDED VACCINE. THE LONG-TERM GOAL IS TO UNDERSTAND GAS SURVIVAL AND PERSISTENCE IN MACROPHAGES TO PROVIDE A CELL- TARGETED BASIS FOR IMPROVED TREATMENT FOR INFECTION. TOWARD THE LONG-TERM GOAL, THE OBJECTIVE IN THIS APPLICATION IS TO EXAMINE MACROPHAGE SECOND-LINE RESPONSES TO GAS FOLLOWING THE FAILURE OF LYSOSOMES TO ELIMINATE BACTERIA. THE CENTRAL HYPOTHESIS IS THAT GAS-INDUCED LYSOSOMAL PERMEABILIZATION ENABLES BACTERIAL AND LYSOSOMAL PROTEINS TO ENTER THE CYTOSOL, WHICH CONTINUES TO ALTER MACROPHAGE CELLULAR PROCESSES, INCLUDING LIMITING THE OXIDATIVE BURST RESPONSE AND INDUCING HISTONE RELEASE AND NON-LYTIC EXOCYTOSIS OF GAS. GUIDED BY PRELIMINARY DATA PRODUCED BY THE APPLICANT’S LABORATORY, THIS HYPOTHESIS WILL BE EXPLORED IN THREE SPECIFIC AIMS. THE WORK IN AIM 1 WILL DETERMINE WHETHER GAS NADASE IN THE CYTOSOL IMPAIRS THE OXIDATIVE BURST RESPONSE. MEASUREMENTS OF REACTIVE OXYGEN SPECIES, CELLULAR ENERGY POOLS, AND NADPH OXIDASE COMPLEX ASSEMBLY WILL DETERMINE WHETHER THIS BACTERIAL ENZYME NEGATIVELY IMPACTS THE MACROPHAGE OXIDATIVE BURST RESPONSE. AIM 2 WILL EXPLORE WHETHER GAS-INDUCED DAMAGE OF THE NUCLEAR ENVELOPE CAUSES DNA-FREE HISTONE RELEASE AND THE EXTENT TO WHICH THESE HISTONES HAVE ANTIMICROBIAL ACTIVITY AGAINST GAS IN THE MACROPHAGE CYTOSOL. PRELIMINARY DATA DEMONSTRATE THAT MACROPHAGES EXPEL GAS IN EXOSOMES AND THE WORK IN AIM 3 WILL CHARACTERIZE THESE GAS- CONTAINING EXOSOMES. TIME-LAPSE MICROSCOPIC OBSERVATIONS WILL BE COMPLEMENTED BY ELECTRON MICROSCOPY AND PROTEOMICS ANALYSES OF ISOLATED EXOSOMES. THE OUTCOME OF THIS WORK WILL INFORM APPROACHES AIMED AT RESTORING OR ENHANCING HOST CELL FUNCTION, WHICH BOTH AVOIDS THE PROBLEMS OF BROAD-SPECTRUM ANTIBIOTIC TREATMENT AND ENHANCES THE NATURAL ABILITY OF MACROPHAGES TO ERADICATE GAS. THE PROPOSED RESEARCH IS INNOVATIVE BECAUSE UNDERSTANDING THESE SECOND-LINE RESPONSES, WHICH ARE INTERMEDIATE PROCESSES BETWEEN LYSOSOMAL FAILURE AND DISEASE PATHOLOGY, WILL PROVIDE NEW DRUGGABLE TARGET PROTEINS AND PATHWAYS. THE CONTRIBUTION WILL BE A SIGNIFICANT FIRST STEP TOWARD DEVELOPING PHARMACOLOGICAL STRATEGIES THAT PREVENT, RATHER THAN TREAT SEVERE INVASIVE DISEASE AND REFRACTORY INFECTIONS.

RUI: COLLABORATIVE RESEARCH: UNDERSTANDING BIOEROSION FROM INDIVIDUALS TO ECOSYSTEMS: THE IMPACTS OF BIOTIC AND ABIOTIC STRESSORS ON SPONGE EROSION OF OYSTER REEFS.

REGIODIVERGENT PALLADIUM-CATALYZED DECARBOXYLATIVE COUPLING OF STABILIZED BENZYLIC NUCLEOPHILES - PROJECT SUMMARY TRANSITION METAL-CATALYZED CARBON-CARBON BOND FORMATION PLAYS A CRITICAL ROLE IN BIOACTIVE SMALL MOLECULE SYNTHESIS, BOTH IN ACADEMIC AND PHARMACEUTICAL INDUSTRY SETTINGS. A PARTICULARLY ATTRACTIVE TOOL IS THE PALLADIUM-CATALYZED DECARBOXYLATIVE ALLYLIC ALKYLATION (DAA) REACTION, WHICH FACILITATES CARBON-CARBON BOND FORMATION VIA THE EXTRUSION OF A SINGLE BYPRODUCT, CARBON DIOXIDE. DESPITE ITS EXTENSIVE APPLICATIONS IN THE PREPARATION OF MEDICINALLY RELEVANT MOLECULES, EXISTING STRATEGIES TO ENGAGE CARBON-CENTERED NUCLEOPHILES IN DAA CHEMISTRY IS LIMITED TO STABILIZED ENOLATE-BASED AND RELATED NUCLEOPHILES WHOSE CONJUGATE ACID PKA IS LESS THAN 25. ON THE OTHER HAND, THE REACTION OF LESS STABILIZED NUCLEOPHILES (CONJUGATE ACID PKA OF > 25) IS LESS WELL DOCUMENTED, IN PART DUE THE ENERGETIC BARRIERS ASSOCIATED WITH PROMOTING THEIR DECARBOXYLATION. ADDITIONALLY, THE MAJORITY OF PD-CATALYZED DECARBOXYLATIVE COUPLINGS PROCEED THROUGH A MECHANISM IN WHICH THE INTERMEDIATE NUCLEOPHILE AND ALLYLPALLADIUM SPECIES REACT TO PREDOMINANTLY DELIVER ALLYLATION PRODUCTS. IN CONTRAST, REPORTS THAT DETAIL THE FORMATION OF THE REGIOISOMERIC CYCLOPROPANATION PRODUCT REMAIN RELATIVELY SCARCE. TO ADDRESS THESE LIMITATIONS, WE HAVE DEVISED A NEW APPROACH THAT RELIES ON THE USE OF AROMATIC ANIONS AS A MEANS TO STABILIZE AND ENGAGE OTHERWISE RECALCITRANT NUCLEOPHILES IN DECARBOXYLATIVE COUPLING CHEMISTRY. SPECIFICALLY, WE RECENTLY DEMONSTRATED THAT ALLYL ESTER-SUBSTITUTED PHTHALIDES UNDERGO EFFICIENT ALLYLATION IN THE PRESENCE OF A PD/XANTPHOS CATALYST, DELIVERING A VARIETY OF FUNCTIONALIZED PHTHALIDES IN EXCELLENT YIELD. INTERESTINGLY, WHEN XANTPHOS IS REPLACED WITH THE BISAMINO LIGAND TETRAMETHYLETHYLENEDIAMINE (TMEDA), A CYCLOPROPANATED PHTHALIDE IS ISOLATED IN HIGH REGIOSELECTIVITY. THE GOAL OF AIM 1 IS TO SIGNIFICANTLY EXPAND ON THESE PRELIMINARY FINDINGS BY APPLYING OUR OPTIMAL PD/XANTPHOS DAA CATALYST TO ACCESS A VARIETY OF BIOLOGICALLY RELEVANT MOTIFS, INCLUDING FUNCTIONALIZED ISOINDOLINONE AND FLUORENE DERIVATIVES. ALTERNATIVELY, AIM 2 SEEKS TO EXPLOIT THE REACTIVITY PD/TMEDA-BASED CATALYST TO DEVELOP A GENERAL DECARBOXYLATIVE CYCLOPROPANATION OF PHTHALIDE-BASED NUCLEOPHILES. FINALLY, THE GOAL OF AIM 3 IS TO ELUCIDATE THE MECHANISTIC BASIS OF THE REGIOSELECTIVITY FOR ALLYLATION VERSUS CYCLOPROPANATION CHEMISTRY VIA STRUCTURAL, KINETIC, AND COMPUTATIONAL STUDIES. THE SUCCESSFUL IMPLEMENTATION OF THIS PROPOSAL CONSTITUTES A SIGNIFICANT EXPANSION OF THE BREADTH OF PD-CATALYZED DECARBOXYLATIVE COUPLING, ESTABLISHING ACCESS TO A WIDER FAMILY OF BIOACTIVE STRUCTURAL MOTIFS WHILE ENGAGING UNDERGRADUATES IN IMPACTFUL YET PRACTICAL RESEARCH ENDEAVORS.

COLLABORATIVE RESEARCH: RUI: CONSTRAINING TROPICAL HYDROCLIMATE RESPONSES TO PERIODS OF ABRUPT HYDROLOGICAL CHANGES USING CAVE DEPOSITS, CAVE MONITORING, AND MODEL OUTPUTS -THE INDIAN PACIFIC WARM POOL LOCATED IN THE TROPICS IS THE HEAT ENGINE OF THE GLOBE. PREVIOUS WORK HAS PROPOSED THAT PAST EPISODIC FRESHWATER FLUXES KNOWN AS HEINRICH EVENTS IN THE NORTHERN HEMISPHERE ABRUPTLY MODULATE TROPICAL HYDROCLIMATE IN REGIONS LIKE THE INDIAN PACIFIC WARM POOL. IN THIS PROJECT, CAVE DEPOSITS FROM THE PHILIPPINES ARE USED TO RECONSTRUCT PAST HYDROLOGIC CHANGE AND INVESTIGATE THE HYDROLOGIC RESPONSE OVER THE INDIAN PACIFIC WARM POOL TO HEINRICH EVENTS. THE PHILIPPINES IS IDEALLY LOCATED FOR THIS WORK AS IT IS SITUATED WITHIN THE INDIAN PACIFIC WARM POOL AND IS SENSITIVE TO SEASONAL VARIATIONS IN RAINFALL ASSOCIATED WITH THE ASIAN MONSOON SYSTEMS. THIS WORK WILL ACCOMPLISH THREE PRIMARY TASKS: FIRST, IT WILL EXPAND CURRENT CAVE MONITORING EFFORTS IN THE PHILIPPINES TO ENCOMPASS A MULTI-YEAR, MULTI-CAVE MONITORING NETWORK TO BETTER CONSTRAIN SEASONAL VARIATIONS IN KARST HYDROLOGY. SECOND, IT WILL CONTRIBUTE NEW HIGH TEMPORAL RESOLUTION CAVE GEOCHEMISTRY RECORDS SPANNING NUMEROUS HEINRICH EVENTS. THIRD, GEOCHEMICAL DATA-MODEL COMPARISONS WILL BE CONDUCTED TO EVALUATE THE MECHANISMS DRIVING GEOCHEMICAL VARIABILITY IN THESE RECORDS DURING HEINRICH EVENTS. RESULTS FROM THIS WORK WILL HELP DEVELOP A FOUNDATIONAL UNDERSTANDING OF RAINFALL PATTERN CHANGES DURING ABRUPT HYDROLOGIC VARIABILITY. BY COMBINING MULTI-YEAR SURFACE AND SUBSURFACE KARST MONITORING WITH NEW CAVE RECORDS, THE INFLUENCE OF NORTHERN HEMISPHERE FRESHWATER FLUXES ON TROPICAL HYDROCLIMATE WILL BE ASSESSED. THE PROJECT WILL ALSO FILL IN SPATIAL GAPS IN THE WESTERN TROPICAL PACIFIC AND IMPROVE MODEL ACCURACY. THIS WORK WILL FORTIFY CONNECTIONS WITH NATIONAL PARKS/PROTECTED LANDSCAPES, UNESCO WORLD HERITAGE STAFF, AND CAVERS. THE TEAM'S FINDINGS WILL BE INCORPORATED IN PAMPHLETS/AUDIO GUIDES AND GUIDED TOURS FOR MILLIONS OF DOMESTIC AND INTERNATIONAL PARK VISITORS. FINALLY, THE PROJECT INCLUDES TRAINING OF MULTIPLE UNDERGRADUATE STUDENTS IN THE GEOSCIENCES AT OCCIDENTAL COLLEGE AND A GRADUATE STUDENT FROM BROWN UNIVERSITY. THIS AWARD REFLECTS NSF'S STATUTORY MISSION AND HAS BEEN DEEMED WORTHY OF SUPPORT THROUGH EVALUATION USING THE FOUNDATION'S INTELLECTUAL MERIT AND BROADER IMPACTS REVIEW CRITERIA.- SUBAWARDS ARE NOT PLANNED FOR THIS AWARD.

CAMPUS BASED-FWS

RUI-CHE: DEVELOPMENT OF ORGANOMETALLIC COMPLEXES FOR THE NEXT-GENERATION OF NON-AQUEOUS REDOX FLOW BATTERIES

CAMPUS BASED-FSEOG

RUI: MARINE VAMPIRE MICROBIOME PROJECT (MVP): BLOOD-FEEDING MARINE INVERTEBRATES, AND THEIR BACTERIAL ACCOMPLICES

OXY SUICIDE PREVENTION PROGRAM - THE OXY SUICIDE PREVENTION PROGRAM IS A COORDINATED, COLLABORATIVE EFFORT TO BRING INTENTIONAL, COMPREHENSIVE SUICIDE-PREVENTION, MENTAL HEALTH PROMOTION, AND SUBSTANCE MISUSE HARM REDUCTION SERVICES TO OCCIDENTAL COLLEGE (OXY). BY BUILDING CAPACITY FOR DATA COLLECTION AND CLINICAL INTERVENTION, INCREASING OPPORTUNITIES FOR PEER EDUCATION AND STUDENT-LED PREVENTION EFFORTS, AND EXPANDING TRAINING FOR SUICIDE-PREVENTION AND REFERRAL SKILLS-BUILDING ACROSS CAMPUS, WE WILL ADDRESS STUDENT NEEDS AND BUILD ROBUST PREVENTION, IDENTIFICATION, AND REFERRAL SUPPORT RELATED TO MENTAL AND SUBSTANCE USE DISORDERS AND SUICIDALITY AMONG OXY STUDENTS. THE PROJECT WILL TAKE AN EVIDENCE-BASED, PUBLIC HEALTH APPROACH TO ADDRESS THE NEEDS OF ALL STUDENTS, WITH A FOCUS ON FIRST-YEAR (27%), STUDENTS OF COLOR (46%), AND LGBTQIA+ IDENTIFYING (46%) STUDENT POPULATIONS, AS WELL AS STUDENTS IN OXY'S STUDY ABROAD AND INTERNATIONAL PROGRAMS, ALL OF WHOM ARE AT GREATER RISK OF NEGATIVE OUTCOMES FROM SUBSTANCE MISUSE, MENTAL HEALTH DISTRESS, AND HAVE REPORTED FEELING LESS SENSE OF CONNECTEDNESS AND BELONGING THAN THEIR COUNTERPARTS ON CAMPUS. THE OVERARCHING GOALS OF THIS PROJECT ARE TO INCREASE HELP-SEEKING BEHAVIORS FOR MENTAL HEALTH AND SUBSTANCE USE ISSUES, TO ENHANCE BELONGING AND CONNECTEDNESS AMONG STUDENTS, AND TO REDUCE SUICIDE AND MENTAL AND SUBSTANCE USE DISORDERS. THERE ARE FOUR MAIN OBJECTIVES: 1. USING A TRAUMA-INFORMED LENS, ENHANCE CLINICAL CAPACITY TO IDENTIFY AND INTERVENE WITH STUDENTS AT RISK FOR SUICIDE, DEPRESSION, SERIOUS MENTAL ILLNESS/SERIOUS EMOTIONAL DISTURBANCES, AND/OR SUBSTANCE MISUSE, AND CONNECT STUDENTS TO TREATMENT AND RECOVERY RESOURCES WHEN NEEDED. -EMMONS WELLNESS CENTER (EMMONS) WILL IMPLEMENT AN SBIRT (SCREENING, BRIEF INTERVENTION, AND REFERRAL TO TREATMENT) MODEL, TRAIN CLINICAL STAFF IN BRIEF MOTIVATIONAL INTERVIEWING, AND INTEGRATE DAST-10 AND CCAPS-36 SCREENING TOOLS DURING CLINICAL VISITS. EMMONS WILL ALSO WORK WITH STUDENT GROUPS AND PARTNER DEPARTMENTS TO DEVELOP SUPPORTIVE RESOURCES FOR STUDENTS ALREADY IN RECOVERY WHO ARE PARTICULARLY MARGINALIZED ON COLLEGE CAMPUSES. 2. EXPAND OUR UNDERSTANDING OF STUDENTS’ CURRENT MENTAL HEALTH, SUBSTANCE USE BEHAVIORS AND EXPERIENCES, RISK FACTORS FOR SUICIDE, AND OXY’S CAPACITY TO MITIGATE THESE FACTORS THROUGH ROBUST DATA COLLECTION AND ASSESSMENT. -EMMONS WILL WORK WITH THE JED FOUNDATION, IN COLLABORATION WITH OXY’S OFFICE OF INSTITUTIONAL RESEARCH AND ASSESSMENT AND A NEWLY CREATED WELL-BEING COMMITTEE, TO ADMINISTER BASELINE AND RECURRING ASSESSMENTS IDENTIFYING STUDENT MENTAL HEALTH AND SUBSTANCE USE NEEDS AND BEHAVIORS, AS WELL AS ASSESS COMMUNITY NEEDS, AND STRATEGICALLY PLAN AND BUILD INFRASTRUCTURE FOR DATA COLLECTION THAT LEADS TO MEASURABLE IMPROVEMENTS IN STUDENT MENTAL HEALTH AND A MORE CONNECTED CAMPUS COMMUNITY. 3. UTILIZE EVIDENCE-BASED PRACTICES TO PROMOTE MENTAL WELL-BEING AND PREVENT SUICIDE THROUGH HARM REDUCTION STRATEGIES, SUICIDE PREVENTION TRAININGS, EDUCATIONAL PROGRAMMING, AND RESTRICTING ACCESS TO MEANS. -EMMONS WILL DEVELOP AND IMPLEMENT SUICIDE-PREVENTION AND REFERRAL SKILLS TRAININGS FOR STUDENTS, STAFF, AND FACULTY GATEKEEPERS, TO ENSURE THE CAMPUS COMMUNITY FEELS COMFORTABLE ADDRESSING ISSUES OF DISTRESSED AND/OR AT-RISK STUDENTS, AND REFERRING THEM TO THE APPROPRIATE RESOURCES IN A TIMELY MANNER. EMMONS WILL IMPLEMENT AWARENESS CAMPAIGNS, EDUCATIONAL MATERIALS, AND PEER-LED OUTREACH EFFORTS DEDICATED TO MENTAL HEALTH PROMOTION, SUICIDE-PREVENTION, AND HARM REDUCTION. 4. PROVIDE MEANINGFUL, INCLUSIVE, STUDENT-LED, SUBSTANCE-FREE PROGRAMMING TO FOSTER POSITIVE COMMUNITY AND CONNECTION, AND A SENSE OF BELONGING AMONG STUDENTS. -EMMONS WILL DEVELOP A MICROGRANT PROGRAM IN WHICH STUDENT ORGANIZATIONS CAN RECEIVE FUNDING TO IMPLEMENT PEER-LED PROGRAMMING, WHICH WILL PROVIDE SPACES FOR STUDENTS TO LEARN ABOUT VARIOUS MENTAL HEALTH TOPICS, COPING AND LIFE SKILLS, AND TO FOSTER CONNECTION AND COMMUNITY BUILDING.

COLLABORATIVE RESEARCH: RUI: LEVERAGING ISOTOPIC COMPOSITIONS OF IGNEOUS SYSTEMS TO RESOLVE THE GEOMETRY AND DISTRIBUTION OF SUBDUCTED SEDIMENT IN THE SOUTHERN U.S. CORDILLERA -QUARTZ-RICH SEDIMENT IS ERODED FROM CONTINENTS AND TRANSPORTED BY RIVERS TO THE OCEANS. SOME OF THIS SEDIMENT IS DEPOSITED IN DEEP OCEANIC TRENCHES AND SUBSEQUENTLY SUBDUCTED BENEATH THE CONTINENTS. BECAUSE THESE SEDIMENTS ARE NOT DENSE ENOUGHT TO SINK INTO THE MANTLE, MUCH OF THE SUBDUCTED SEDIMENT IS THOUGHT TO BECOME RE-INCORPORATED INTO THE CONTINENTS. THIS RE-ADDITION OF SUBDUCTED SEDIMENT TO THE BASE OF CONTINENTS CAN HELP UNDERSTANDING OF THE PATTERNS OF DEFORMATION AND THE DISTRIBUTION OF ELEMENTS WITHIN THE CONTINENT. IT CAN POTENTIALLY REDUCE THE STRENGTH OF TECTONIC PLATES, SO THAT SOME ZONES MAY BE MORE PRONE TO FAULTING AND SEISMIC ACTIVITY. INTRODUCING SEDIMENT INTO THE LITHOSPHERE CAN ALSO RECHARGE THE ELEMENTS THAT HAVE PREVIOUSLY BEEN DEPLETED BY TECTONIC PROCESSES, INCLUDING CRITICAL MINERALS. ONE OF THE FUNDAMENTAL CHALLENGES THIS RESEARCH ADDRESSES IS DETERMINING THE DISTRIBUTION AND GEOMETRY OF SUBDUCTED SEDIMENT IN THE CONTINENTAL CRUST. THIS PROJECT ESTABLISHES A NEW COLLABORATION AND PROVIDES SUPPORT FOR TWO EARLY-CAREER RESEARCHERS AND FIVE UNDERGRADUATE STUDENTS FROM HISTORICALLY MARGINALIZED AND UNDERREPRESENTED GROUPS AT TWO DIFFERENT UNIVERSITIES. THE STUDENTS RECEIVE TRAINING IN A VARIETY OF GEOLOGIC FIELD METHODS, CONDUCT CHEMICAL AND ISOTOPIC ANALYSES AT MULTIPLE UNIVERSITY LABORATORIES OUTSIDE OF THEIR HOME INSTITUTIONS, AND DEVELOP EFFECTIVE SCIENCE COMMUNICATION SKILLS. END-MEMBER MODELS FOR THE GEOMETRY OF SUBDUCTED SEDIMENT AT DEPTH INCLUDE REPLACEMENT OF THE CRUSTAL MATERIALS WITH UNIFORM, SHEET-LIKE LAYERS OF SEDIMENT AND NON-UNIFORM, DIAPIR-LIKE BODIES DISTRIBUTED THROUGHOUT THE CRUST. THIS RESEARCH WILL TEST THESE MODELS IN SOUTHERN CALIFORNIA AND ARIZONA, WHICH EXPERIENCED WIDESPREAD SEDIMENT SUBDUCTION AND ACCRETION DURING THE LATE CRETACEOUS TO EARLY PALEOGENE. THE SUBDUCTED SEDIMENT, LOCALLY CALLED THE PELONA-OROCOPIA-RAND SCHIST (?OROCOPIA SCHIST?), HAS BEEN TECTONICALLY EXHUMED TO THE SURFACE ALLOWING FOR DIRECT INVESTIGATION INTO ITS STRUCTURAL AND CHEMICAL PROPERTIES. THE OROCOPIA SCHIST HAS A UNIQUE COMBINATION OF JUVENILE RADIOGENIC ISOTOPIC COMPOSITIONS AND HEAVY STABLE OXYGEN ISOTOPE RATIOS, WHICH DISTINGUISHES IT FROM OTHER MAJOR ISOTOPIC RESERVOIRS IN THE AREA. RECENT STUDIES AND PRELIMINARY DATA INDICATE THAT IGNEOUS ROCKS THAT TRANSVERSED THE CRUST DURING THE MID-CENOZOIC IGNIMBRITE FLARE-UP IN AREAS WHERE THE OROCOPIA SCHIST IS PRESENT RECORD THE UNIQUE ISOTOPIC SIGNATURE, WHEREAS MAGMATISM OUTSIDE OF THIS AREA DOES NOT. ADDITIONALLY, IGNEOUS ROCKS THAT INTRUDED INTO THE CRUST PRIOR TO ACCRETION OF THE OROCOPIA SCHIST DO NOT FEATURE THE UNIQUE ISOTOPIC FINGERPRINT. AS A RESULT, THIS RESEARCH USES IGNEOUS ROCKS IN THE REGION AS A ?DEEP-CRUSTAL PROBE? TO IDENTIFY REFINE THE GEOMETRY OF SUBDUCTED SEDIMENT IN THE SUBSURFACE. THIS AWARD REFLECTS NSF'S STATUTORY MISSION AND HAS BEEN DEEMED WORTHY OF SUPPORT THROUGH EVALUATION USING THE FOUNDATION'S INTELLECTUAL MERIT AND BROADER IMPACTS REVIEW CRITERIA.- SUBAWARDS ARE NOT PLANNED FOR THIS AWARD.

COLLABORATIVE RESEARCH: RUI: EAR-CLIMATE: INVESTIGATING THE PAST, PRESENT, AND FUTURE OF GLACIATED ALPINE LANDSCAPES USING AN INTEGRATED DATA-MODEL APPROACH -TODAY, 80% OF ALL GLACIERS ARE SMALLER THAN 0.5 KM2, AND MANY LARGER VALLEY GLACIERS ARE IN THE PROCESS OF TRANSITIONING TO SMALL CIRQUE GLACIERS IN RESPONSE TO MODERN WARMING. DESPITE THEIR SMALL SIZE, CIRQUE GLACIERS PLAY AN OUTSIZED GEOMORPHIC AND ECOLOGICAL ROLE IN ALPINE LANDSCAPES, LARGELY THROUGH REGIONALLY VARIABLE CHANGES IN HYDROLOGY AND SEDIMENT TRANSPORT. UNDERSTANDING HOW THESE GLACIERS RESPONDED TO PAST CLIMATE CHANGES AND HOW THEY WILL RESPOND TO FUTURE CLIMATE CHANGES IS PREREQUISITE FOR UNDERSTANDING THE PAST EVOLUTION AND FUTURE FATE OF ALPINE CATCHMENTS IN THE WESTERN U.S. AND ELSEWHERE. THIS PROJECT WILL ADDRESS THIS NEED BY DEVELOPING DETAILED GLACIOLOGICAL DATASETS, BOTH MODERN AND PALEO, FROM AN EXCEPTIONALLY WELL-CONSTRAINED STUDY SITE IN THE TETON RANGE, WYOMING, AND INTEGRATING THEM WITH A STATE-OF-THE-ART MODEL TO ACCURATELY REPRESENT GLACIERS AS THEY SHRINK AND DISAPPEAR. ULTIMATELY, THIS WORK WILL PRODUCE INSIGHT INTO THE PAST, PRESENT, AND FUTURE ROLE OF GLACIERS AS AGENTS OF ALPINE LANDSCAPE EVOLUTION WHILE DEVELOPING AN OPEN-SOURCE GLACIER MODEL, WHICH WILL BE APPLICABLE TO GLACIAL SETTINGS GLOBALLY. THE PROJECT WILL ALSO FOSTER NEW COLLABORATIONS BETWEEN FOUR EARLY CAREER PIS, IMPROVE STEM EDUCATION AT TWO PUBLIC RESEARCH INSTITUTIONS AND ONE LIBERAL ARTS COLLEGE THROUGH INCREASED PARTICIPATION OF UNDERREPRESENTED MINORITIES IN THE EARTH SCIENCES, AND PROMOTE CLIMATE SCIENCE LITERACY AND PUBLIC ENGAGEMENT. THIS RESEARCH WILL ADVANCE OUR FUNDAMENTAL UNDERSTANDING OF DEGLACIATION IN ALPINE LANDSCAPES BY INTEGRATING DIVERSE DATASETS INTO A NEW GLACIER MODEL TO SIMULATE PAST AND ONGOING GLACIER RETREAT IN THE WESTERN U.S. THIS MODEL REPRESENTS A TRANSFORMATIVE ADVANCE IN THAT IT INCLUDES NOVEL REPRESENTATION OF TOPOGRAPHICALLY-MEDIATED EFFECTS ON MASS BALANCE?PROCESSES THAT ARE INCREASINGLY IMPORTANT AS GLACIERS SHRINK INTO SHADED CIRQUES. IMPORTANTLY, THE NEW OPEN-SOURCE GLACIER MODEL (PYG2D) CAN BE APPLIED TO OTHER SETTINGS WORLDWIDE TO QUANTIFY THE EFFECTS OF CLIMATE CHANGE ON MOUNTAIN ECOSYSTEMS, HYDROLOGY, AND LANDSCAPES. BY APPLYING AND TESTING THIS MODEL IN THE TETON RANGE, A SITE WITH EXCEPTIONAL GEOLOGIC CONSTRAINTS ON PAST GLACIER FLUCTUATIONS AND A SUITE OF CIRQUE GLACIERS THAT ARE REPRESENTATIVE OF SMALL GLACIERS GLOBALLY, THIS PROJECT WILL PRODUCE THE FIRST DETAILED SIMULATIONS OF FUTURE GLACIER EVOLUTION IN THE CONTIGUOUS U.S. WE WILL PLACE MODERN AND FUTURE GLACIER CHANGE IN CONTEXT BY CONSTRAINING AND SIMULATING GLACIER STATES FROM THE LAST ICE AGE TO 2100 CE. THIS WORK, WHILE FOCUSED ON A SINGLE NATURAL LABORATORY, HAS BROAD IMPLICATIONS FOR GLACIERIZED REGIONS ELSEWHERE ON THE PLANET AND OFFERS AN IMPORTANT SPACE-FOR-TIME SUBSTITUTION TO INFORM HOW MORE HEAVILY GLACIATED LANDSCAPES WILL EVOLVE IN THE FUTURE. WITH A CONTINUOUS RECORD OF GLACIER EXTENT, THICKNESS, AND VOLUME THIS WORK WILL LAY THE FOUNDATION FOR FUTURE STUDIES, BOTH GEOMORPHIC AND ECOLOGICAL IN SCOPE, THAT QUANTIFY THE IMPACT OF GLACIER CHANGE ON ALPINE LANDSCAPES FACING COMPLETE DEGLACIATION. ANTICIPATED RESULTS WILL SERVE AS KEY EXAMPLES OF THE TANGIBLE IMPACTS OF CLIMATE CHANGE ON THE CRYOSPHERE THAT CAN BE READILY UNDERSTOOD BY RESOURCE MANAGERS, POLICYMAKERS, AND THE BROADER PUBLIC. THIS AWARD REFLECTS NSF'S STATUTORY MISSION AND HAS BEEN DEEMED WORTHY OF SUPPORT THROUGH EVALUATION USING THE FOUNDATION'S INTELLECTUAL MERIT AND BROADER IMPACTS REVIEW CRITERIA.

COLLABORATIVE RESEARCH: REDEFINING THE FOOTPRINT OF DEEP OCEAN METHANE SEEPAGE FOR BENTHIC ECOSYSTEMS

COLLABORATIVE RESEARCH: THE DRIVERS OF REGIONALLY COHERENT MERIDIONAL VARIABILITY ACROSS THE AUSTRALIAN AND ASIAN MONSOONS OVER THE COMMON ERA -THE EASTERN HEMISPHERE TROPICS AND SUBTROPICS ARE HIGHLY SENSITIVE TO VARIATIONS IN REGIONAL MONSOON PRECIPITATION, WHICH PROVIDES THE MAJORITY OF FRESHWATER FOR THE ~40% OF THE WORLD POPULATION WHO RESIDE THERE. UNDERSTANDING INTERANNUAL TO MULTIDECADAL VARIATIONS IN THE MONSOON IS CRITICAL FOR MANAGING WATER RESOURCES. THIS PROJECT WILL COMPILE DATA FROM CAVE DEPOSITS, CORALS AND TREE RINGS, AS WELL AS DEVELOP NEW RECORDS FROM CAVES IN THE PHILIPPINES AND NORTHERN AUSTRALIA, TO PRODUCE A RECONSTRUCTION OF THE BEHAVIOR OF THE AUSTRAL-ASIAN MONSOON FOR THE LAST 1000 YEARS. THIS RECONSTRUCTION WILL GUIDE A SET OF CLIMATE MODEL SIMULATIONS TO IDENTIFY THE DRIVERS OF MONSOON VARIABILITY. THE RESULTS WILL IMPROVE DECADAL PREDICTION THE AUSTRAL-ASIAN MONSOON. THE PROJECT WILL SUPPORT THE PARTICIPATION OF A POSTDOC AND UNDERGRADUATE STUDENTS IN THE RESEARCH, AN ART-SCIENCE COLLABORATION, K-12 EDUCATION, AND PUBLIC OUTREACH TO PRIMARY AND SECONDARY STUDENTS IN IOWA, CALIFORNIA, NEW MEXICO AND NORTHERN AUSTRALIA. THE GOAL OF THIS PROJECT IS TO SYNTHESIZE EXISTING DATA FROM STALAGMITES, CORALS AND TREE RINGS WITH NEW CAVE RECORDS FROM THE PHILIPPINES AND NORTHERN AUSTRALIA TO RECONSTRUCT THE AUSTRAL-ASIAN MONSOON FOR THE LAST 1000 YEARS. THE RESULTING MULTI-PROXY RECONSTRUCTION WILL GUIDE A SUITE OF CLIMATE MODEL SIMULATIONS, INCLUDING LARGE ENSEMBLES AND ISOTOPE-ENABLED MODELS, TO IDENTIFY DRIVERS OF MONSOON VARIABILITY AND QUANTIFY THE RELATIVE CONTRIBUTIONS OF EXTERNAL (SOLAR, AEROSOL, GREENHOUSE GAS) AND INTERNAL (TROPICAL BASIN INTERACTIONS) FORCINGS. THE RESULTS WILL IMPROVE DECADAL PREDICTION THE AUSTRAL-ASIAN MONSOON. THE PROJECT WILL SUPPORT THE PARTICIPATION OF A POSTDOC AND UNDERGRADUATE STUDENTS IN THE RESEARCH, AN ART-SCIENCE COLLABORATION, K-12 EDUCATION, AND PUBLIC OUTREACH TO PRIMARY AND SECONDARY STUDENTS IN IOWA, CALIFORNIA, NEW MEXICO AND NORTHERN AUSTRALIA. THIS AWARD REFLECTS NSF'S STATUTORY MISSION AND HAS BEEN DEEMED WORTHY OF SUPPORT THROUGH EVALUATION USING THE FOUNDATION'S INTELLECTUAL MERIT AND BROADER IMPACTS REVIEW CRITERIA.- SUBAWARDS ARE NOT PLANNED FOR THIS AWARD.

COLLABORATIVE RESEARCH: EVALUATING TECTONIC MODELS FOR THE WESTERN US CORDILLERA THROUGH THE METAMORPHIC HISTORY OF THE PELONA-OROCOPIA-RAND SCHISTS -APPARENT INCONSISTENCIES BETWEEN DIFFERENT GEOLOGIC AND GEOPHYSICAL DATASETS HAVE RESULTED IN DECADES OF ACTIVE DEBATE ABOUT HOW WESTERN NORTH AMERICA WAS FORMED. ONE OF THE LONGEST-HELD MODELS INVOKES A SHALLOW SUBDUCTING OCEANIC PLATE BENEATH THE MOJAVE DESERT TO WYOMING TO LARGE-SCALE MOUNTAIN BUILDING AS FAR EAST AS THE ROCKY MOUNTAINS. THIS STUDY TESTS THE VIABILITY OF THE FLAT SLAB MODEL AGAINST ALTERNATIVE HYPOTHESES, INCLUDING THE COLLISION AND TRANSLATION OF A FAR-TRAVELED TERRANE, THROUGH DETAILED STUDY OF THE PELONA-OROCOPIA-RAND SCHIST. THIS SUITE OF ANCIENT METAMORPHIC ROCKS SPAN FROM CALIFORNIA TO ARIZONA, A CRITICAL LOCATION TO DISTINGUISH BETWEEN THE TECTONIC MODELS. THE RESEARCHERS WILL TEST PREDICTIONS ABOUT THE LOCATION, CONDITIONS, AND TIMING OF TECTONIC EVENTS DERIVED FROM STANDARD RECYCLING OF OCEANIC CRUST, FLAT SLAB SUBDUCTION, AND TERRANE COLLISION BY DETERMINING THE AGE, PRESSURE, AND TEMPERATURE RECORDED BY THE METAMORPHIC MINERAL GARNET IN THE PELONA-OROCOPIA-RAND SCHIST. THE PROJECT WILL PROMOTE THE DEVELOPMENT OF TWO EARLY-CAREER WOMEN IN STEM, FOSTER NEW COLLABORATIONS ACROSS R1, R2, AND PUI CAMPUSES, FACILITATE THE TRAINING OF GRADUATE AND UNDERGRADUATE STUDENTS FROM UNDERREPRESENTED GROUPS, AND SUPPORT THE DEVELOPMENT OF ANALYTICAL FACILITIES. THE PROPOSED CONTRIBUTION PROVIDES A CRUCIAL TEST OF CONFLICTING MODELS FOR THE TECTONIC EVOLUTION OF THE WESTERN NORTH AMERICAN CORDILLERA BY RE-EVALUATING THE METAMORPHIC HISTORY OF THE PELONA-OROCOPIA-RAND SCHIST USING MODERN TECHNIQUES. THE RESEARCHERS WILL ESTIMATE THE CONDITIONS OF METAMORPHISM USING HIGH RESOLUTION ANALYTICAL METHODS AND A VARIETY OF MODERN MODELING TECHNIQUES, INCLUDING RAMAN SPECTROSCOPY, BULK CHEMICAL ANALYSIS, AND P-T MODELING. THE TIMING OF EVENTS WILL BE EVALUATED USING GARNET SM-ND AND MONAZITE U-(TH)-PB GEOCHRONOLOGY. THEY WILL PROVIDE A UNIFYING REGIONAL DATASET BY SAMPLING ACROSS THE FULL EXTENT OF DOCUMENTED OUTCROPS RATHER THAN USING A SITE-SPECIFIC APPROACH. THE WORK WILL SUPPORT TWO GRADUATE STUDENTS FROM NORTHERN ILLINOIS UNIVERSITY AND THE UNIVERSITY OF ALABAMA AS WELL AS UNDERGRADUATE STUDENT RESEARCH AT OCCIDENTAL COLLEGE. THIS AWARD REFLECTS NSF'S STATUTORY MISSION AND HAS BEEN DEEMED WORTHY OF SUPPORT THROUGH EVALUATION USING THE FOUNDATION'S INTELLECTUAL MERIT AND BROADER IMPACTS REVIEW CRITERIA.- SUBAWARDS ARE NOT PLANNED FOR THIS AWARD.

SATELLITE MONITORING OF RIVERS: A DISTRIBUTED-SAMPLING APPROACH TO IMPROVE SATELLITE ESTIMATES OF RIVER WATER QUALITY ON A GLOBAL SCALE

IGF::OT::IGF CSPI FALL 2016 TUITION

IGF::OT::IGF CSPI SPRING 2017 TUITION

IGF::OT::IGF CSPI SPRING 2016 TUITION CSPI STUDENT: OT CHARLES JOHNSON STUDENT ID: A01129673 OCCIDENTAL COLLEGE 1600 CAMPUS ROAD LOS ANGELES, CA 90041 POINT OF CONTACT INFORMATION: NAME:YADIRA BARAJAS PHONE:323-259-2610 TAS: 070/2016/2016/0610/000

IGF::OT::IGF CSPI FALL 2015 TUITION CSPI STUDENT: OT CHARLES JOHNSON STUDENT ID: A01129673 OCCIDENTAL COLLEGE 1600 CAMPUS ROAD LOS ANGELES, CA 90041 POINT OF CONTACT INFORMATION: NAME:YADIRA BARAJAS PHONE:323-259-2610 TAS: 070/2015/2015/0610/000

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