ARIZONA STATE UNIVERSITY

MID-SCALE RI-2 CONSORTIUM: COMPACT X-RAY FREE-ELECTRON LASER PROJECT (CXFEL) -MODERN SCIENCE QUESTIONS ACROSS MANY DISCIPLINES INCREASINGLY FOCUS ON UNDERSTANDING EVENTS, CHANGES, AND STRUCTURES AT THE SMALLEST ATOMIC SCALES. THE ESTABLISHMENT OF A COMPACT X-RAY FREE ELECTRON LASER (CXFEL) FACILITY AT ARIZONA STATE UNIVERSITY WILL ENABLE THESE ADVANCED STUDIES AND FULFILL AN URGENT NEED IN THE BROAD U.S. RESEARCH COMMUNITY TO DIRECTLY OBSERVE, MANIPULATE, AND CONTROL QUANTUM DYNAMICS IN COMPLEX MATERIALS, MOLECULES, AND INTERFACES. THESE CAPABILITIES WILL REVEAL NOVEL BIOLOGICAL PROCESSES, ENABLE NEW ENERGY-EFFICIENT TECHNOLOGIES, AND DECODE QUANTUM BEHAVIOR THAT CAN DRIVE NEW COMPUTING METHODS AND NOVEL MATERIALS. A DIVERSE POPULATION OF UNDERGRADUATE AND GRADUATE STUDENTS WILL BE ENGAGED IN THE SCIENTIFIC AND PROJECT MANAGEMENT ASPECTS OF THIS MID-SCALE RESEARCH INFRASTRUCTURE DEVELOPMENT EFFORT. THE COMBINATION OF INFRASTRUCTURE TRAINING AND BROAD RESEARCHER ACCESS TO TRANSFORMATIVE NEW INSTRUMENTS WILL SERVE THE NSF MISSION PRIORITY TO ADVANCE ALL FIELDS OF SCIENCE AND ENGINEERING. THE CXFEL IS A NOVEL INSTRUMENT TO PRODUCE SUB-FEMTOSECOND COHERENT X-RAYS FOR ANALYSIS OF A RANGE OF SAMPLES. CXFEL BUILDS ON THE LATEST ADVANCES IN LASER TECHNOLOGY AND ELECTRON BEAM PHYSICS TO PRODUCE A ROOM-SIZED X-RAY LASER (ROUGHLY 10M LONG) WITH FULL COHERENCE IN TIME AND SPACE. THE CXFEL WILL UNIQUELY OFFER FULL CONTROL OF THE X-RAY PHASE USING ELECTRON-BEAM PATTERNING THAT ALLOWS CUSTOMIZED TIME-STRUCTURE OF THE BEAM, E.G., ATTOSECOND PULSES, VERY NARROW LINEWIDTHS, AND EXTREMELY PRECISE TIMING AMONG MULTIPLE PULSES WITH DIFFERENT COLORS. MULTIPLE END-STATIONS WILL BE CONFIGURED TO SUPPORT X-RAY SPECTROSCOPY, SMALL- AND WIDE-ANGLE X-RAY SCATTERING, COINCIDENT ATTOSECOND MOMENTUM IMAGING, AND TIME-RESOLVED X-RAY CRYSTALLOGRAPHY FOR STUDIES IN BIOLOGY, QUANTUM MATERIALS, ATOMIC AND MOLECULAR SCIENCE, AND OPTICAL SCIENCES. DURING CONSTRUCTION, SOPHISTICATED MACHINE LEARNING SOFTWARE WILL BE INTEGRATED WITH THE HARDWARE TO CREATE HIGHLY FLEXIBLE AND EFFICIENT ULTRAFAST SCIENCE INSTRUMENTS THAT RESPOND TO NSF?S BIG IDEAS, INCLUDING MIDSCALE RESEARCH INFRASTRUCTURE, RULES OF LIFE, QUANTUM LEAP, AND HARNESSING THE DATA REVOLUTION. THE SOFTWARE TOOLS WILL HELP GUIDE ACQUISITION AND ANALYSIS OF LARGE DATA SETS, SPEEDING UP EXPERIMENTS AND EXPANDING CAPABILITIES. THE PRIMARY OUTCOME OF THE CXFEL PROJECT IS CONSTRUCTION OF A USER-FACILITY WITH INSTRUMENTS AND END-STATIONS, INCLUDING VALIDATION OF ALGORITHMS AND EXPERIMENTAL CAPABILITIES. THE RESULTING FACILITY WILL BE ACCESSIBLE TO A NATIONALLY AND INTERNATIONALLY DISTRIBUTED GROUP OF INVESTIGATORS FROM A RANGE OF DIFFERENT SCIENTIFIC DISCIPLINES. THIS AWARD REFLECTS NSF'S STATUTORY MISSION AND HAS BEEN DEEMED WORTHY OF SUPPORT THROUGH EVALUATION USING THE FOUNDATION'S INTELLECTUAL MERIT AND BROADER IMPACTS REVIEW CRITERIA.

IGF::CL,CT::IGF PSYCHE: JOURNEY TO A METAL WORLD THIS CONTRACT PROVIDES FOR WORK TO BE PERFORMED BY THE PRINCIPAL INVESTIGATOR IN SUPPORT OF THE PHASE A CONCEPT DEFINITION PORTION OF THE NASA DISCOVERY PROGRAM 2014 ANNOUNCEMENT OF OPPORTUNITY (AO) (NNH14ZDA014O) SOLICITATION DATED NOVEMBER 5, 2014. THE MISSION PRINCIPAL INVESTIGATOR (PI), DR. LINDA ELKINS-TANTON, OF THE SCHOOL OF EARTH AND SPACE EXPLORATION AT ARIZONA STATE UNIVERSITY (ASU), IS RESPONSIBLE FOR THE SUCCESS AND SCIENTIFIC INTEGRITY OF THE MISSION. AS SUCH, THE PI SHALL LEAD THE PROJECT, MANAGE PROJECT RESOURCES, AND DIRECT ALL ACTIVITIES OF THE SCIENCE TEAM CARRIED OUT IN SUPPORT OF THE MISSION. SPECIFICALLY, DURING PHASE A, THE PI WILL LEAD THE MISSION TEAM IN CONDUCTING THE CONCEPT STUDY REPORT AND ASSOCIATED SITE VISIT. SHOULD THE MISSION BE SELECTED TO CONTINUE INTO PHASE B, THE PI WILL LEAD THE TEAM THROUGH THE INITIATION OF THE PHASE B EFFORT WITH A TRANSITION PHASE BETWEEN NOTIFICATION OF AWARD AND ESTABLISHMENT OF THE PHASE B CONTRACT. THE PI IS ASSISTED BY A DEPUTY PI, DR. JAMES BELL AT ARIZONA STATE UNIVERSITY. JET PROPULSION LABORATORY (JPL) IS THE MISSION MAJOR PARTNER FOR SPACECRAFT DEVELOPMENT AND MISSION IMPLEMENTATION, AND SHALL SUPPORT THE PI WITH A PROJECT TEAM EXPERIENCED IN MANAGEMENT, SYSTEMS ENGINEERING, MISSION DESIGN, PAYLOAD DEVELOPMENT, SAFETY AND MISSION ASSURANCE, NAVIGATION, AND MISSION OPERATIONS. SPECIFIC OBJECTIVES TO ADDRESS THE PHASE A CRITERIA AND GUIDELINES ARE: - PROJECT MANAGEMENT FOR THE PHASE A CONTRACT - CONDUCT AND SUPPORT OF PHASE A PROJECT REVIEWS - PHASE B/C/D/E SPACECRAFT DEVELOPMENT AND MISSION PLANNING - PHASE B/C/D/E COST ESTIMATES - CONCEPT STUDY REPORT PREPARATION - ORALS/SITE VISIT SUPPORT BY KEY PERSONNEL THIS CONTRACT PROVIDES FOR WORK TO BE PERFORMED BY THE PRINCIPAL INVESTIGATOR IN SUPPORT OF THE PHASE A CONCEPT DEFINITION PORTION OF THE NASA DISCOVERY PROGRAM 2014 ANNOUNCEMENT OF OPPORTUNITY (AO) (NNH14ZDA014O) SOLICITATION DATED NOVEMBER 5, 2014. THE MISSION PRINCIPAL INVESTIGATOR (PI), DR. LINDA ELKINS-TANTON, OF THE SCHOOL OF EARTH AND SPACE EXPLORATION AT ARIZONA STATE UNIVERSITY (ASU), IS RESPONSIBLE FOR THE SUCCESS AND SCIENTIFIC INTEGRITY OF THE MISSION. AS SUCH, THE PI SHALL LEAD THE PROJECT, MANAGE PROJECT RESOURCES, AND DIRECT ALL ACTIVITIES OF THE SCIENCE TEAM CARRIED OUT IN SUPPORT OF THE MISSION. SPECIFICALLY, DURING PHASE A, THE PI WILL LEAD THE MISSION TEAM IN CONDUCTING THE CONCEPT STUDY REPORT AND ASSOCIATED SITE VISIT. SHOULD THE MISSION BE SELECTED TO CONTINUE INTO PHASE B, THE PI WILL LEAD THE TEAM THROUGH THE INITIATION OF THE PHASE B EFFORT WITH A TRANSITION PHASE BETWEEN NOTIFICATION OF AWARD AND ESTABLISHMENT OF THE PHASE B CONTRACT. THE PI IS ASSISTED BY A DEPUTY PI, DR. JAMES BELL AT ARIZONA STATE UNIVERSITY. JET PROPULSION LABORATORY (JPL) IS THE MISSION MAJOR PARTNER FOR SPACECRAFT DEVELOPMENT AND MISSION IMPLEMENTATION, AND SHALL SUPPORT THE PI WITH A PROJECT TEAM EXPERIENCED IN MANAGEMENT, SYSTEMS ENGINEERING, MISSION DESIGN, PAYLOAD DEVELOPMENT, SAFETY AND MISSION ASSURANCE, NAVIGATION, AND MISSION OPERATIONS. SPECIFIC OBJECTIVES TO ADDRESS THE PHASE A CRITERIA AND GUIDELINES ARE: - PROJECT MANAGEMENT FOR THE PHASE A CONTRACT - CONDUCT AND SUPPORT OF PHASE A PROJECT REVIEWS - PHASE B/C/D/E SPACECRAFT DEVELOPMENT AND MISSION PLANNING - PHASE B/C/D/E COST ESTIMATES - CONCEPT STUDY REPORT PREPARATION - ORALS/SITE VISIT SUPPORT BY KEY PERSONNEL

ENGINEERING RESEARCH CENTER FOR BIO-MEDIATED AND BIO-INSPIRED GEOTECHNICS (CBBG)

THE ARIZONA STATE UNIVERSITY SCHOOL OF EARTH AND SPACE EXPLORATIONS PROPOSAL, NASA SMD EXPLORATION CONNECTION, WILL ADDRESS THE NEED FOR GREATER U.S.

IGF::OT::IGF NASA IS SOLICITING PROPOSALS FOR SCIENTIFIC INSTRUMENTS THAT MIGHT REVEAL ANSWERS ABOUT LUNAR RESOURCES THAT COULD SUPPORT THE AGENCY'S JOURNEY TO MARS. NASA WOULD SPONSOR THE INSTRUMENTS TO FLY ON A LUNAR ORBITER DESIGNED BY THE KOREA AEROSPACE RESEARCH INSTITUTE (KARI). THE SPACECRAFT, THE KOREA PATHFINDER LUNAR ORBITER (KPLO), IS SCHEDULED TO LAUNCH IN DECEMBER 2018, AND IS PART OF KARI'S KOREA LUNAR EXPLORATION PROGRAM, WHICH AIMS TO ROBOTICALLY EXPLORE THE MOON THROUGH A SERIES OF ORBITER AND LANDER MISSIONS, STARTING WITH THE KPLO. KARI, HEADQUARTERED IN DAEJEON, SOUTH KOREA, PROVIDED NASA WITH ABOUT 33 POUNDS (15 KILOGRAMS) OF PAYLOAD MASS ABOARD THE KPLO, WHICH IS SCHEDULED TO LAUNCH INTO LUNAR ORBIT IN DECEMBER 2018. IN SEPTEMBER 2016, NASA ISSUED A SOLICITATION SEEKING SCIENCE INSTRUMENTS THAT COULD INCREASE OUR UNDERSTANDING OF THE DISTRIBUTION OF VOLATILES, SUCH AS WATER, INCLUDING THE MOVEMENT OF SUCH RESOURCES TOWARD PERMANENTLY SHADOWED REGIONS AND HOW THEY BECOME TRAPPED THERE. SHADOWCAM WILL MAP THE REFLECTANCE WITHIN THE PERMANENTLY SHADOWED REGIONS TO SEARCH FOR EVIDENCE OF FROST OR ICE DEPOSITS. THE INSTRUMENT'S OPTICAL CAMERA IS BASED ON THE LUNAR RECONNAISSANCE ORBITER NARROW ANGLE CAMERA, BUT IS 800 TIMES MORE SENSITIVE, ALLOWING IT TO OBTAIN HIGH-RESOLUTION, HIGH SIGNAL-TO-NOISE IMAGING OF THE MOON'S PERMANENTLY SHADOWED REGIONS. SHADOWCAM WILL OBSERVE THE PSRS MONTHLY TO DETECT SEASONAL CHANGES AND MEASURE THE TERRAIN INSIDE THE CRATERS, INCLUDING THE DISTRIBUTION OF BOULDERS. NASA'S ADVANCED EXPLORATION SYSTEMS DIVISION (AES) LED THE PAYLOAD SOLICITATION AND SELECTION FOR THE NASA INSTRUMENT ON KPLO. A DIVISION OF THE HUMAN EXPLORATION AND OPERATIONS MISSION DIRECTORATE, AES USES INNOVATIVE APPROACHES AND PUBLIC-PRIVATE PARTNERSHIPS TO RAPIDLY DEVELOP PROTOTYPE SYSTEMS, ADVANCE KEY CAPABILITIES, AND VALIDATE OPERATIONAL CONCEPTS FOR FUTURE HUMAN MISSIONS BEYOND EARTH ORBIT. THROUGH THIS PARTNERSHIP OPPORTUNITY WITH KARI, AES IS ADDRESSING KEY LUNAR SKGS WHILE COMPLEMENTING KARI'S PRIMARY MISSION OBJECTIVES AND INSTRUMENTS.

CRITICAL FUNCTIONS IN THE PERFORMANCE OF THIS EFFORT THE CONTRACTOR IS THE ARIZONA STATE UNIVERSITY, SCHOOL OF EARTH AND SPACE EXPLORATION (SESE). ASU SHALL DIRECT ALL ASPECTS OF THE PROJECT DEVELOPMENT AND PROJECT SCIENCE EFFORTS, AND PROVIDE THE NECESSARY PERSONNEL, FACILITIES, SERVICES, AND MATERIALS TO DESIGN, FABRICATE, ASSEMBLE, INTEGRATE, AND TEST THE OSIRIS-REX OTES, ALONG WITH THE NECESSARY SOFTWARE AND GROUND SUPPORT EQUIPMENT TO SUPPORT THE OSIRIS-REX LAUNCH. AFTER LAUNCH, ASU SHALL PROVIDE SUPPORT FOR OTES PHASE E MISSION OPERATIONS: PHASE E WORK IS NOT COVERED UNDER THIS SOW. INSTEAD, OTES SUPPORT FOR PHASE E IS COVERED UNDER THE SPOC SOW. THE SCOPE OF ASU S WORK SHALL INCLUDE, BUT NOT BE LIMITED, TO THE FOLLOWING: 1. MANAGE THE OTES TEAM THROUGH PHASE B, C, AND D OF THE OSIRIS-REX MISSION. 2. DEFINE THE REQUIREMENTS FOR OTES IN AGREEMENT WITH LEVEL-1 REQUIREMENTS. 3. DEVELOP A PRELIMINARY DESIGN FOR THE OTES INSTRUMENT THAT MEETS THE OTES SCIENCE GOALS AND OBJECTIVES, AND REQUIREMENTS. 4. DESIGN, DEVELOP, FABRICATE, INTEGRATE, TEST, AND DELIVER A FLIGHT-QUALIFIED OTES INSTRUMENT TO MEET THE OTES SCIENCE GOALS AND OBJECTIVES, AND REQUIREMENTS. 5. VALIDATE THE LEVEL 1 REQUIREMENTS THAT APPLY TO OTES AS WELL THE MISSION PERFORMANCE REQUIREMENTS. 6. INTEGRATE THE OTES INSTRUMENT ON THE FLIGHT SYSTEM AND SUPPORT FLIGHT SYSTEM LEVEL TESTING. 7. DEFINE THE SCIENCE DATA PROCESSING ALGORITHMS REQUIRED FOR THE MISSION. 8. SUPPORT THE DEVELOPMENT AND TESTING OF THE OTES FLIGHT SOFTWARE AT LOCKHEED MARTIN (REFERRED TO AS LM FROM THIS POINT FORWARD). 9. SUPPORT THE DEVELOPMENT OF THE OTES STANDARD DATA PROCESSING PIPELINE SOFTWARE TOOLS FOR THE SPOC AT UA. THIS DOES NOT INCLUDE SCIENCE DATA PROCESSING SOFTWARE TOOLS, FOR EXAMPLE J-ASTEROID VISUALIZATION SOFTWARE FOR SPOC SCIENCE OPERATIONS. 10. IMPLEMENT THE OTES MISSION ASSURANCE PROGRAM IN ACCORDANCE WITH THE OSIRIS-REX MISSION ASSURANCE REQUIREMENTS (MAR). 11. PROVIDE SYSTEMS ENGINEERING SUPPORT TO MISSION DESIGN AND SPACECRAFT ACCOMMODATIONS. 12. MAINTAIN THE REQUIRED INTERNATIONAL TRAFFIC IN ARMS REGULATIONS (ITAR) AND EXPORT CONTROL DOCUMENTATION NECESSARY FOR WORKING WITH ANY INTERNATIONAL TEAM MEMBERS. 13. POVIDE SUPPORT FOR THE OSIRIS-REX EDUCATION AND PUBLIC OUTREACH (EPO) PROGRAM THAT IS BEING LED BY UNIVERSITY OF ARIZONA AND THE NASA OSIRIS-REX PROJECT OFFICE. 14. EVELOP AND DELIVER THE CONTRACT DATA REQUIREMENTS IDENTIFIED IN THE OSIRIS-REX CONTRACT DATA REQUIREMENTS LIST (CDRL). 15. PRESENT AND PARTICIPATE IN THE OSIRIS-REX MISSION DESIGN REVIEW, THE MISSION LEVEL PRELIMINARY DESIGN REVIEW AND THE MISSION LEVEL CRITICAL DESIGN REVIEW.

ARIZONA ALZHEIMER'S DISEASE RESEARCH CENTER - OVERALL — PROJECT SUMMARY/ABSTRACT OVER THE LAST 20 YEARS, ARIZONA RESEARCHERS ESTABLISHED NIA'S FIRST STATEWIDE ALZHEIMER'S DISEASE CENTER AND THE NATION'S MOST EXTENSIVE STATEWIDE COLLABORATION IN ALZHEIMER'S DISEASE (AD) RESEARCH. THEY MADE PIONEERING CONTRIBUTIONS TO THE UNUSUALLY EARLY DETECTION, TRACKING AND STUDY OF AD AND THE ACCELERATED EVALUATION OF AD PREVENTION THERAPIES. THE CENTER INCLUDES RESEARCHERS FROM SEVEN ORGANIZATIONS, SIX IN THE PHOENIX METROPOLITAN AREA AND ONE IN TUCSON. IT HAS SUPPORTED 150 RESEARCHERS FROM ORGANIZATIONS ACROSS THE STATE AND HELPING THEM TO GENERATE MORE THAN $2 BILLION IN NEW GRANTS, CONTRACTS, PHILANTHROPIC, STATE AND ORGANIZATIONAL INVESTMENTS. THE ARIZONA AD RESEARCH CENTER (ADRC) WILL CAPITALIZE ON THE CENTER'S LEADERSHIP, STATEWIDE COLLABORATIVE MODEL, MAJOR ORGANIZATIONAL COMMITMENTS, AND EXTENSIVELY SHARED SCIENTIFIC RESOURCES AND ITS VERY EXISTENCE TO MAKE THE SCIENTIFIC FIGHT AGAINST AD A TOP PRIORITY IN THE STATE. ITS RESOURCES, STRATEGIC PLAN, AND RELATED PROGRAMS AND PREVENTION TRIALS ARE SPECIFICALLY INTENDED TO SET THE STAGE FOR PROMISING BLOOD TESTS TO TRANSFORM AD/ADRD RESEARCH, TREATMENT DEVELOPMENT, AND CARE, INCLUDE PERSONS FROM DIVERSE BACKGROUNDS, FIND AN EFFECTIVE PREVENTION THERAPY BY 2025, AND FULFILL NATIONAL ALZHEIMER'S PROJECT ACT (NAPA) GOALS. WE WILL USE ADRC, ORGANIZATIONAL AND PHILANTHROPIC FUNDS TO PROVIDE AN EXTRAORDINARY RESOURCE OF DATA AND BLOOD SAMPLES FOR NEUROPATHOLOGICAL STUDY AND DIAGNOSTIC VALIDATION OF BBBS FOR ADRD USING BLOOD SAMPLES FROM SEVERAL HUNDRED BRAIN DONORS IN THE LAST YEARS OF LIFE WHO HAVE COMPREHENSIVE NEUROPATHOLOGICAL ASSESSMENTS AFTER THEY DIE. THE OVERALL GOALS OF THE CENTER WILL BE ACCOMPLISHED THROUGH COORDINATED ACTIVITIES OF ITS SIX CORES AND THE RESEARCH EDUCATION COMPONENT (REC). THE ADMINISTRATIVE CORE WILL PROVIDE THE SCIENTIFIC LEADERSHIP TO THE ADRC AS A WHOLE. THE MULTI-SITE CLINICAL CORE WILL PERFORM STANDARD EVALUATIONS AND COLLECT UDS AND ADDITIONAL DATA ON ALL PARTICIPANTS, INCLUDING A LARGE NUMBER OF HISPANIC/LATINO AND NATIVE AMERICAN PARTICIPANTS. THE NEUROPATHOLOGY CORE WILL PROVIDE NEUROPATHOLOGIC DIAGNOSES AND PROCESS, STORE AND DISTRIBUTE POSTMORTEM BRAIN TISSUE, INCLUDING FROM THOSE WHO PROVIDED BLOOD SAMPLES IN THE LAST 1-2 YEARS OF THEIR LIVES. THE BIOMARKER CORE WILL SUPPORT AND PROVIDE ACCESS TO GENETICS, BRAIN IMAGING (MRI, AMYLOID PET, TAU PET), CEREBROSPINAL FLUID (CSF) AND BBBS OF AD. THE OUTREACH, RECRUITMENT AND ENGAGEMENT (ORE) CORE WILL SUPPORT THE EFFORTS OF THE CLINICAL AND NEUROPATHOLOGY CORE, PROVIDING A RANGE OF EDUCATIONAL AND OUTREACH PROGRAMS FOR HEALTHY ADULTS, PATIENTS AND FAMILY CAREGIVERS IN OUR CENTER'S CATCHMENT AREA, INCLUDING FROM ARIZONA'S LARGE HISPANIC/LATINO AND NATIVE AMERICAN COMMUNITIES. THE DATA MANAGEMENT AND STATISTICS CORE WILL SUPPORT ALL THE DATA MANAGEMENT, INFORMATICS AND STATISTICAL NEEDS OF THE CORES AND CENTER. THE REC WILL COORDINATE CLOSELY WITH EACH OF THE CORES AND LEVERAGE EXTERNAL PARTNERSHIP WITH TWO RESOURCE CENTERS FOR MINORITY AGING RESEARCH (RCMARS) TO ATTRACT AND SUPPORT THE DEVELOPMENT OF NEW RESEARCHERS AND CLINICIANS. TOGETHER THESE ACTIVITIES WILL HELP SET THE STAGE FOR BBBS TO REVOLUTIONIZE ADRD RESEARCH, TREATMENT AND CARE, INFORM THE STUDY OF PRECLINICAL AD, AND HELP PROVIDE THE BEST POSSIBLE CHANGE TO FIND AND SUPPORT THE APPROVAL OF AN AD PREVENTION THERAPY IN 2025.

NSF I-CORPS HUB (TRACK 1): DESERT AND PACIFIC REGION -THE BROADER IMPACT/COMMERCIAL POTENTIAL OF THIS NSF I-CORPS HUBS PROJECT IS THE DEVELOPMENT OF A PARTNERSHIP SPANNING FIVE STATES, FROM THE DESERT REGION OF THE WEST TO THE PACIFIC, TO INCREASE ECONOMIC COMPETITIVENESS AND SOCIETAL BENEFIT THROUGH ADVANCING UNIVERSITY-DEVELOPED, DEEP TECHNOLOGY VENTURES TO LOCAL, REGIONAL, AND NATIONAL MARKETS. THIS DELIBERATE PARTNERING OF SMALL, MEDIUM, AND LARGE INSTITUTIONS IS PREDICATED ON INSTITUTIONAL ALIGNMENT, COMBINING EMERGING AND MATURE CULTURES OF INNOVATION, AND RECIPROCAL EAGERNESS TO COLLABORATE TO STRENGTHEN INNOVATION CAPACITY. THE HUB PROVIDES ACCESS TO A RICH NETWORK OF INNOVATION PRACTICES AND RESOURCES TO DIVERSE COMMUNITIES OF INNOVATORS WHILE REDUCING PARTICIPATION BARRIERS FOR BOTH EXPERIENCED AND LESS EXPERIENCED INSTITUTIONS. IN ADDITION, THE HUB INCREASES CAPACITY FOR INNOVATION DEVELOPMENT BY EXPANDING CONVENTIONAL GEOGRAPHIES OF INNOVATION TO DISCONNECTED AREAS THAT ARE TYPICALLY OUTSIDE OF VENTURE DEVELOPMENT HUBS AND CONNECTS THEM TO MORE EXPERIENCED AND RESOURCE-RICH AREAS. THE HUB SHARES KNOW-HOW, RESOURCES, AND CONNECTIONS TO PROVIDE I-CORPS TRAINING VIRTUALLY AND IN MULTIPLE FORMATS. THE REGIONAL TRAINING IS DESIGNED TO ADDRESS SKILLS AND KNOWLEDGE GAPS TO ACCELERATE AND SUSTAIN DEEP TECHNOLOGY VENTURES ACROSS THE REGION. THE HUB LEVERAGES A DIVERSE, POOLED NETWORK OF MENTORS AND INDUSTRY EXPERTS TO REDUCE TIME AND RISK IN THE CREATION OF NEW VENTURES. ALSO, THE HUB IS RESPONSIVE TO SECURING NATIONAL DEFENSE, BUILDING ON NSF?S INVESTMENTS IN CYBERSECURITY, NOVEL MATERIALS, AND ADVANCED ANALYTICS, BY SPECIFICALLY IDENTIFYING, ADDRESSING, AND SUPPORTING DUAL-USE TECHNOLOGIES. THIS I-CORPS DESERT AND PACIFIC REGION HUB PROJECT IS BASED ON THE DEVELOPMENT OF A NETWORK THAT ADVANCES AND DEEPENS THE REGENERATIVE INNOVATION CAPACITY OF THE PARTNERING INSTITUTIONS, PROVIDING MEANINGFUL EXPERIENTIAL DEVELOPMENT OPPORTUNITIES FOR FACULTY, RESEARCHERS, STUDENTS, AND COLLABORATORS THROUGH DIRECT ENTREPRENEURIAL ENGAGEMENTS AND SKILLS DEVELOPMENT. THE HUB FACILITATES INTENTIONAL GROUP LEARNING THROUGH A DEEPLY NETWORKED COMMUNITY OF PRACTICE, INCLUDING I-CORPS INSTRUCTORS, MENTORS, ADMINISTRATORS, FACULTY, AND STUDENTS IDEALLY POSITIONED TO COLLECTIVELY SUPPORT THE ACADEMIC COMMUNITY IN TRANSLATING RESEARCH INTO DEEP TECHNOLOGY VENTURES, REGARDLESS OF LOCATION. THE HUB ALSO SEEKS TO DIMINISH DISADVANTAGES, SUCH AS THE LACK OF MATURE ASSETS EQUAL TO THOSE IN HISTORICALLY ADVANTAGED AND RESOURCE-RICH LOCALES. THIS HUB PROVIDES QUALITY AND FLEXIBILITY, WHILE ENABLING PARTICIPATING INSTITUTIONS TO INCORPORATE STRUCTURED ENTREPRENEURIAL TRAINING AND SUPPORT IN A PROVEN ONLINE METHOD. BUILDING ON A BODY OF SCHOLARSHIP, A NETWORK FOCUSED ON DEVELOPING THE ENTREPRENEURIAL MINDSET, ADDITIVE AND AGILE INNOVATION, CURRICULAR ADAPTATIONS, ORGANIZATIONAL AND INFRASTRUCTURE SUPPORT INCLUDING DISTRIBUTED MENTOR MODELS AND SHARED CUSTOMER DATABASES, AND THE UTILIZATION OF INNOVATIVE TOOLS, THE HUB ADVANCES ENTREPRENEURIAL PROGRAMMING AND RESEARCH TO INFORM I-CORPS PRACTICE, ILLUMINATE NATIONAL TRENDS, AND INFLUENCE ORGANIZATIONAL AND NATIONAL POLICY. THIS AWARD REFLECTS NSF'S STATUTORY MISSION AND HAS BEEN DEEMED WORTHY OF SUPPORT THROUGH EVALUATION USING THE FOUNDATION'S INTELLECTUAL MERIT AND BROADER IMPACTS REVIEW CRITERIA.

MID-SCALE RI-1 (MI:IP): FACILITY FOR OPEN RESEARCH IN A COMPRESSED ENVIRONMENT (FORCE) AT ARIZONA STATE UNIVERSITY

CHECRS: COGNITIVE HUMAN ENHANCEMENTS FOR CYBER REASONING SYSTEMS

INTERGOVERNMENTAL SUPPORT AGREEMENT (IGSA) BETWEEN AIR UNIVERSITY (AU) AND ARIZONA STATE UNIVERSITY (ASU) FOR LEARNING MANAGEMENT SYSTEM (LMS) AND STUDENT INFORMATION SYSTEM (SIS).

BII: MECHANISMS OF CELLULAR EVOLUTION

IRREGULAR WARFARE CENTER RESEARCH SUPPORT SERVICES

BASE PERIOD

ARIZONA CANCER AND EVOLUTION CENTER (ACE)

HARNESSING AUTONOMY FOR COUNTERING CYBER-ADVERSARY SYSTEMS (HACCS) - UNDER TA2, PHASES I, II&III, ARIZONA STATE UNIVERSITY WILL CREATE A NEW FRAMEWORK, CALLED CONTROL MODULO THEORY (CMT), THAT SUPPORTS SOPHISTICATED REASONING ABOUT VULNERABILITIES, WITH THE GOAL OF CREATING A SYSTEM THAT IS ABLE TO COMBINE MULTIPLE N-DAY VULNERABILITIES TO ACHIEVE CONTROL OVER A REMOTE TARGET TO OVERCOME CURRENT LIMITATIONS IN SOFTWARE DEFENSE.

GRADUATE RESEARCH FELLOWSHIP PROGRAM (GRFP) -THE NATIONAL SCIENCE FOUNDATION (NSF) GRADUATE RESEARCH FELLOWSHIP PROGRAM (GRFP) IS A HIGHLY COMPETITIVE, FEDERAL FELLOWSHIP PROGRAM. GRFP HELPS ENSURE THE VITALITY AND DIVERSITY OF THE SCIENTIFIC AND ENGINEERING WORKFORCE OF THE UNITED STATES. THE PROGRAM RECOGNIZES AND SUPPORTS OUTSTANDING GRADUATE STUDENTS WHO ARE PURSUING RESEARCH-BASED MASTER'S AND DOCTORAL DEGREES IN SCIENCE, TECHNOLOGY, ENGINEERING, AND MATHEMATICS (STEM) AND IN STEM EDUCATION. THE GRFP PROVIDES THREE YEARS OF FINANCIAL SUPPORT FOR THE GRADUATE EDUCATION OF INDIVIDUALS WHO HAVE DEMONSTRATED THEIR POTENTIAL FOR SIGNIFICANT RESEARCH ACHIEVEMENTS IN STEM AND STEM EDUCATION. THIS AWARD SUPPORTS THE NSF GRADUATE FELLOWS PURSUING GRADUATE EDUCATION AT THIS GRFP INSTITUTION. THIS AWARD REFLECTS NSF'S STATUTORY MISSION AND HAS BEEN DEEMED WORTHY OF SUPPORT THROUGH EVALUATION USING THE FOUNDATION'S INTELLECTUAL MERIT AND BROADER IMPACTS REVIEW CRITERIA.

ASU GEAR UP

THE TROPICAL PACIFIC ISLANDS REGION, ENCOMPASSING OVER 300,000 SQUARE MILES OF LAND AND MILLIONS OF SQUARE MILES OF OCEAN, HAS HISTORICALLY EXPERIENCED A HIGH BURDEN OF CLIMATE DISASTERS SUCH AS TROPICAL CYCLONES, DROUGHT, WILDFIRE, FLOODING, AND SEA LEVEL RISE, WITH WELL-DOCUMENTED IMPACTS ON FOOD AND WATER SECURITY, HUMAN HEALTH AND SAFETY, INFRASTRUCTURE, ECOSYSTEMS, AND GEOPOLITICAL STABILITY. PHYSICAL, POLITICAL, AND SOCIAL FACTORS DIRECTLY CONTRIBUTE TO HOW DIFFERENT ISLAND COMMUNITIES AND JURISDICTIONS EXPERIENCE, PREPARE FOR, AND RESPOND TO THESE IMPACTS, ANDAS THE COVID-19 PANDEMIC HAS DEMONSTRATEDCOMPOUND EVENTS HAVE DISPROPORTIONATE EFFECTS ON POPULATIONS THAT HAVE BEEN MADE MORE VULNERABLE TO PHYSICAL AND SOCIAL RISKS. UNDERSTANDING THE RISKS AND VULNERABILITIES OF DIFFERENT COMMUNITIES, ORGANIZATIONS, AND INFRASTRUCTURE ACROSS THE REGION IS STILL A CRITICAL ISSUE FOR PRIORITIZING AND FUNDING CLIMATE ADAPTATION PROJECTS, AND THE IMPACTS OF COMPOUND AND CORRELATE

RESEARCH IAW SOW: DARPA ASSURED MICROPATCHING (AMP). THIS EFFORT IS IN SUPPORT OF TECHNICAL AREA 1: GOAL-DRIVEN DECOMPILATION (TA1)

ASU R&D PROJECT UNDER ARPA-H SHARE DIGIHEALS BAA

THIS AWARD FUNDS THE APPROVED 2024-2025 AMERICORPS NATIONAL DIRECT PROGRAM. NO MEMBER MAY ENROLL PRIOR TO THE APPROVED START DATE OF THE MEMBER ENROLLMENT PERIOD. YOUR 2024-2025 REGULATORY MATCH IS 0% AND YOUR BUDGETARY MATCH IS 25.74%.

START UP/ENROLLMENT PERIOD

THE MAIN GOAL OF THE HIGHER EDUCATION PARTNERSHIP-MOROCCO PROGRAM IS TO ASSIST THE MINISTRY OF EDUCATION, VOCATIONAL TRAINING, HIGHER EDUCATION AND SCIENTIFIC RESEARCH (MOE) IN THE IMPLEMENTATION OF THE NEWLY ADOPTED LAW (LOI CADRE) FOR TEACHER PREPARATION TO IMPROVE PRE-SERVICE TEACHER TRAINING.

COMMUNITY HEALTH WORKERS FOR COVID-19 RESPONSE AND RESILIENCY: NATIONAL EVALUATION TEAM

THIS PROJECT WILL CREATE A SUSTAINABLE PROCESS THROUGH WHICH EARTH AND SPACE SCIENCE AND ENGINEERING (ESSE) SUBJECT MATTER EXPERTS (SME) ESPECIALLY NASA-FUNDED SMES WILL JOIN EDUCATION EXPERTS FROM THE SCIENCE ACTIVATION PROGRAM (SCIACT) TO FORM THE

LEAD APPLICANT ORGANIZATION NAME: ARIZONA STATE UNIVERSITYLEAD APPLICANT ENTITY TYPE: INSTITUTION OF HIGHER EDUCATION AS DEFINED IN SECTION 101(A) OF THE HIGHER EDUCATION ACT OF 1965 (20 U.S.C. 1001)LEAD APPLICANT LOCATION: TEMPE, ARIZONAEMPLOYER PARTNERS: CENTRAL ARIZONA COLLEGE COCHISE COLLEGE, COCONINO COMMUNITY COLLEGE, CREIGHTON UNIVERSITY, EASTERN ARIZONA COLLEGE, MARICOPA COMMUNITY COLLEGE (REPRESENTING 8 MARICOPA NURSING CAMPUSES), NORTHERN ARIZONA UNIVERSITY, PIMA COMMUNITY COLLEGE, UNIVERSITY OF ARIZONA, YAVAPAI COLLEGE.EDUCATION PARTNERS: ARIZONA STATE UNIVERSITYNAME OF THE STATE APPRENTICESHIP AGENCY: NOT APPLICABLENAMES OF ENTITIES INVOLVED IN ADMINISTERING THE WORKFORCE DEVELOPMENT SYSTEM: ARIZONA WORK WORKFORCE DEVELOPMENT BOARDS OF PHOENIX AND MARICOPA COUNTY WORKER ORGANIZATIONS, LABOR-MANAGEMENT ORGANIZATIONS, OR LABOR UNIONS: ARIZONA STATE BOARD OF NURSING, ARIZONA NURSES ASSOCIATION, AMERICAN ASSOCIATION OF NURSE ANESTHESIOLOGY, AMERICAN COLLEGE OF NURSE-MIDWIVES ARIZONA AFFILIATE, ARIZONA LEAGUE FOR NURSING, GREATER PHOENIX AREA CHAPTER OF THE AMERICAN ASSOCIATION OF CRITICAL-CARE NURSES, ARIZONA KOREAN NURSES ASSOCIATION, ASSOCIATION OF PERIOPERATIVE NURSES, BLACK NURSES ASSOCIATION - GREATER PHOENIX AREA.OPTIONAL PARTNERS: ARIZONA ADVISORY COUNCIL ON INDIAN HEALTH CARE, GILA RIVER HEALTHCARE, NATIVE HEALTH PHOENIX, RIVER PEOPLE HEALTH CENTER, SAN CARLOS APACHE HEALTHCARE, DIGNITY YAVAPAI REGIONAL MEDICAL CENTER, KINGMAN REGIONAL MEDICAL CENTER, MT. GRAHAM REGIONAL MEDICAL CENTER, ABRAZO CARONDELET HEALTH, ABRAZO SCOTTSDALE HEALTH, BANNER HEALTH, HONORHEALTH, MAYO CLINIC, VALLEYWISE HEALTHGEOGRAPHIC SCOPE: ARIZONA-WIDE SPECIFIC LOCATIONS (COUNTIES): COCHISE, COCONINO, GRAHAM, MARICOPA, PIMA, PINAL, YAVAPAITOTAL MATCH PROPOSED (TOTAL 5-YEAR PERIOD): 1,104,470PROJECT TITLE: ARIZONA NURSING FACULTY EXPANSION PROJECTPROPOSED NUMBER OF PARTICIPANTS WHO START TRAINING: 140SUMMARY OF PROJECT PURPOSE AND EMPLOYMENT AND TRAINING ACTIVITIES OFFERED: THE EDSON COLLEGE AT ARIZONA STATE UNIVERSITY (ASU) WILL FILL THE CURRENT NURSING WORKFORCE GAP THROUGH AN AA BS TO MS PROGRAM DELIVERED TO 140 NURSING FACULTY ACROSS ARIZONA IN THE NEXT FIVE YEARS. IN PARTICULAR, THE NURSING EXPANSION PROGRAM AT ASU, FUNDED BY THE DEPARTMENT OF LABOR, WILL PARTNER WITH ARIZONAS STRONG COMMUNITY COLLEGE NURSING PROGRAM LEADERSHIP AND ARIZONAS DIVERSITY OF LABOR ORGANIZATIONS TO RECRUIT UNDERQUALIFIED NURSING INSTRUCTORS, WITH A FOCUS ON RURAL AND UNDERREPRESENTED GROUPS, TO PROVIDE LOW-COST, EASY ACCESS TO A NATIONALLY RANKED NURSING EDUCATOR PROGRAM. THE GOAL OF THE PROGRAM IS TO INCREASE THE CAPACITY OF INSTRUCTIONAL FACULTY, IMPROVE THE QUALITY OF INSTRUCTION, AND INCREASE THE REPRESENTATION OF CULTURAL, RACIAL, AND SOCIOECONOMIC BACKGROUNDS IN THE NURSING FACULTY ACROSS THE STATE. THIS, IN TURN WILL IMPROVE THE QUALITY OF GRADUATED NURSES STATE-WIDE. ULTIMATELY, THE PROGRAM WILL CONTRIBUTE TO RECRUITMENT OF A DIVERSE NURSING STUDENT BODY, PREPARED TO ENTER THE NURSING PROFESSION MOTIVATED BY NURSING INSTRUCTORS WITH MS DEGREE QUALIFICATIONS THAT REFLECT THE COMMUNITIES THEY SERVE.TARGETED POPULATION(S) TO BE SERVED: UNDEREMPLOYED, AND OR INCUMBENT WORKERS FROM HISTORICALLY MARGINALIZED AND UNDERREPRESENTED POPULATIONS, INCLUDING PEOPLE OF COLOR. STATEWIDE RECRUITMENT WILL INCLUDE RURAL AND UNDERREPRESENTED NURSES ACROSS GEOGRAPHIC HPSA REGIONS IN ARIZONA.TRAINING TRACK (SELECT ONE): 1. NURSE EDUCATION PROFESSIONALTARGETED H-1B OCCUPATIONS (MUST MATCH OCCUPATIONS LISTED IN APPLICATION)THE APPLICATION WILL TRAIN PARTICIPANTS FOR OCCUPATIONS ALONG CAREER PATHWAYS LEADING TOMIDDLE- TO HIGH-SKILLED H-1B HEALTHCARE OCCUPATIONS IDENTIFIED IN APPENDIX A:1. HEALTH SPECIALTIES TEACHERS, POSTSECONDARY, O NET CODE 25-1071.00, O NET JOB ZONE 52. NURSING INSTRUCTORS AND TEACHERS, POSTSECONDARY, O NET CODE 25-1072.00, O NET JOB ZONE 5

ENGAGING HISPANIC COMMUNITIES IN AUTHENTIC NASA SCIENCE: BROADENING PARTICIPATION IN SCIENCE ACTIVATION THROUGH LOCAL PARTNERSHIPS AND NATIONAL NETWORKS (ENGAGING HISPANIC COMMUNITIES)

PROWESS WILL COMBINE EMERGING HIGH-DENSITY RECONFIGURABLE PROCESSING ARRAYS WITH EMBEDDED REAL-TIME SCHEDULERS TO EXPOSE NEW ARCHITECTURAL TRADEOFFS THAT JOINTLY DELIVER HIGH COMPUTE DENSITY AND FAST PROGRAM SWITCHING

NIGMS NATIONAL AND REGIONAL RESOURCES - DNASU

COMPREHENSIVE RESOURCE FOR THE DROSOPHILA 4TH CHROMOSOME

GLOBAL CENTERS TRACK 1: GLOBAL HYDROGEN PRODUCTION TECHNOLOGIES (HYPT) CENTER -HYDROGEN PRODUCED WITH NET-ZERO EMISSIONS OF CARBON DIOXIDE IS CALLED GREEN HYDROGEN. LARGE-SCALE GREEN HYDROGEN PRODUCTION IS ESSENTIAL TO MEET THE PARIS AGREEMENT?S CLIMATE GOALS WHILE MAINTAINING THE ECONOMIC PRODUCTIVITY VITAL TO SOCIETAL WELLBEING. GREEN HYDROGEN ENABLES THE DECARBONIZATION OF ENERGY-INTENSIVE INDUSTRIES SUCH AS AMMONIA AND STEEL PRODUCTION, AND TRANSPORTATION. HOWEVER, GREEN HYDROGEN IS CURRENTLY SEVERAL TIMES MORE EXPENSIVE THAN HYDROGEN PRODUCED FROM FOSSIL FUELS. THIS HINDERS ITS GLOBAL ADOPTION. THE GLOBAL HYDROGEN PRODUCTION TECHNOLOGIES (HYPT) CENTER ENGAGES A COMPREHENSIVE, MULTIDISCIPLINARY TEAM TO FORMULATE A PATHWAY TO LOW-COST LARGE-SCALE GREEN HYDROGEN PRODUCTION FROM A PLATFORM OF COMPLEMENTARY TECHNOLOGIES. THE RESEARCHERS?34 EXPERTS FROM 19 INSTITUTIONS IN THE U.S., AUSTRALIA, CANADA, UK, EGYPT AND GERMANY?DEVELOP NEW TECHNOLOGIES AND EXPLORE NOVEL POLICIES AND ECONOMICAL MODELS TO BUILD A STRONG HYDROGEN ECONOMY. THIS AWARD ALSO PROVIDES SUPPORT AND TRAINING TO GRADUATE STUDENTS AT ARIZONA STATE UNIVERSITY, AS WELL AS TO EARLY CAREER SCIENTISTS AT STANFORD UNIVERSITY AND THE UNIVERSITY OF MICHIGAN. THE CENTER FOSTERS OUTREACH TO INDIGENOUS PEOPLES IN THE U.S., AUSTRALIA, AND CANADA. THE AIM IS TO ENGAGE THESE COMMUNITIES IN ADOPTING RENEWABLE ENERGY TECHNOLOGIES AND GIVE THEM ACCESS TO EDUCATIONAL AND CAREER OPPORTUNITIES IN THIS FIELD. THE GLOBAL HYPT CENTER FOCUSES ON THREE MAJOR GREEN HYDROGEN PRODUCTION TECHNOLOGIES WITH STRONG POTENTIAL TO DELIVER BREAKTHROUGHS: (I) WATER ELECTROLYSIS INCLUDING RENEWABLE ENERGY INTEGRATION AND EMERGING ELECTROLYZERS; (II) METHANE PYROLYSIS WITH SOLID CARBON AS VALUE-ADDED CO-PRODUCTS; AND (III) PHOTOCATALYTIC SOLAR WATER SPLITTING. THE CENTER ALSO TACKLES TWO MAJOR CROSS-CUTTING CHALLENGES FOR GREEN HYDROGEN: (I) POLICIES, ECONOMICS, AND MARKETS FOR BUILDING A HYDROGEN ECONOMY; AND (II) WATER RESOURCE AND TREATMENT FOR ELECTROLYSIS AND PHOTOCATALYSIS. THE COMMON UNDERLYING SCIENTIFIC CHALLENGE FOR ALL THREE GREEN HYDROGEN PRODUCTION TECHNOLOGIES IS REACTION KINETICS. AT THE MATERIALS LEVEL, IT REQUIRES INNOVATIONS IN CATALYSTS, WHERE MATERIAL COST, PERFORMANCE, AND CRITICALITY ARE THE PRIMARY CONCERNS. AT THE DEVICE LEVEL, REACTION KINETICS CAN BE ACCELERATED WITH IMPROVED MASS AND HEAT TRANSPORT. AT THE SYSTEM AND APPLICATION LEVELS, EACH TECHNOLOGY FACES A UNIQUE SET OF CHALLENGES IN ENGINEERING AND SOCIO-ECONOMIC DIMENSIONS. THE CENTER INTERWEAVES RESEARCHERS WITH DIVERSE EXPERTISE FROM DIFFERENT COUNTRIES UNDER THESE THRUST AREAS TO WORK SYNERGISTICALLY WITH THE GOAL OF LOW-COST (US$1/KG) AND LARGE-SCALE (GIGATONS A YEAR) GREEN HYDROGEN PRODUCTION. THIS AWARD IS FUNDED BY THE GLOBAL CENTERS PROGRAM, AN INNOVATIVE PARTNERSHIP WITH FUNDING AGENCIES IN AUSTRALIA, CANADA AND THE UNITED KINGDOM, TO JOINTLY SUPPORT USE-INSPIRED RESEARCH ADDRESSING GLOBAL CHALLENGES IN CLIMATE CHANGE AND CLEAN ENERGY. PARTNERSHIPS WITH THE COMMONWEALTH SCIENCE AND INNOVATION RESEARCH ORGANISATION (CSIRO), NATURAL SCIENCE AND ENGINEERING RESEARCH COUNCIL OF CANADA (NSERC), SOCIAL SCIENCE AND HUMANITIES RESEARCH COUNCIL OF CANADA (SSHRC), AND UK RESEARCH AND INNOVATION (UKRI) LEVERAGE RESOURCES TO TACKLE CHALLENGES AT A LARGER SCALE THAN WOULD BE POSSIBLE FOR ONE FUNDING AGENCY ALONE. THIS CENTER IS JOINTLY SUPPORTED BY NSF, CSIRO, NSERC, AND UKRI. THIS AWARD REFLECTS NSF'S STATUTORY MISSION AND HAS BEEN DEEMED WORTHY OF SUPPORT THROUGH EVALUATION USING THE FOUNDATION'S INTELLECTUAL MERIT AND BROADER IMPACTS REVIEW CRITERIA.- SUBAWARDS ARE PLANNED FOR THIS AWARD.

GREATER PHOENIX URBAN FORESTRY ACCELERATOR

BAA 23-0017 UNIVERSITY OF ARIZONA "ACCELERATE MATERIALS DESIGN AND PROCESS OPTIMIZATION THROUGH ARTIFICIAL INTELLIGENCE AND MACHINE LEARNING"

CHILDHOOD OBESITY AMONG IMPOVERISHED MEXICAN AMERICANS: LONGITUDINAL GROWTH PATTERNS AND CULTURAL-BIOECOLOGICAL PREDICTORS FROM BIRTH TO PRE-PUBERTY.

SCIACT STEM ECOSYSTEMS TO BROADEN PARTICIPATION IN AUTHENTIC STEM LEARNING: CONNECTING SUBJECT MATTER EXPERTS COMMUNITIES AND LEARNERS OF ALL AGES ("SCIACT STEM ECOSYSTEMS")

IGF::CL,CT::IGF RESEARCH AND DEVELOPMENT SERVICES FOR THE DEPARTMENT OF HOMELAND SECURITY, SCIENCE AND TECHNOLOGY DIRECTORATE, CHEMICAL AND BIOLOGICAL DEFENSE DIVISION IN SUPPORT OF THE DEVELOPMENT OF A BROAD-SPECTRUM DIAGNOSTIC TO ENABLE TRIAGE IN EMERGENCY RESPONSE SCENARIOS TO OPTIMIZE MEDICAL ACTIONS AND DECISIONS AND AS A POTENTIAL METHOD THAT CAN PROVIDE A DISEASE AGNOSTIC TOOL FOR DETECTION AND IDENTIFICATION OF INFECTIOUS DISEASES.

LTER: CAP V: INVESTIGATING HOW RELATIONSHIPS BETWEEN URBAN ECOLOGICAL INFRASTRUCTURE AND HUMAN-ENVIRONMENT INTERACTIONS SHAPE THE STRUCTURE AND FUNCTION OF URBAN ECOSYSTEMS -HUMANKIND IS INCREASINGLY AN URBAN SPECIES AND URBAN ECOSYSTEMS ARE THEREFORE PROFOUNDLY IMPORTANT. CITIES ARE CONCENTRATED CONSUMERS OF ENERGY AND RESOURCES AND PRODUCERS OF VARIOUS WASTES, BUT THEY ARE ALSO CENTERS OF SOCIAL NETWORKS, INNOVATION, EFFICIENCY, AND SOLUTIONS. THE CENTRAL ARIZONA?PHOENIX LONG TERM ECOLOGICAL RESEARCH PROGRAM (CAP V) IS A RESEARCH PROJECT THAT INCLUDES SCIENTISTS FROM A VARIETY OF DISCIPLINES FOCUSED ON UNDERSTANDING CITIES AS HYBRID ECOSYSTEMS INCLUDING BOTH ENVIRONMENTAL AND HUMAN COMPONENTS, AND THEIR INTERACTIONS. UNDERSTANDING URBAN ECOSYSTEMS REMAINS THE CENTRAL FOCUS OF CAP V AFTER 25 YEARS OF INNOVATIVE RESEARCH. THE INTERCONNECTEDNESS OF HUMAN MOTIVATION, BEHAVIOR, ACTIONS, AND OUTCOMES WITH URBAN ECOSYSTEM STRUCTURE AND FUNCTION LEADS TO A FUNDAMENTAL QUESTION ADDRESSED BY THIS PROJECT. HOW HAVE/ARE HUMAN-ENVIRONMENT INTERACTIONS MEDIATED BY URBAN ECOLOGICAL INFRASTRUCTURE TO SHAPE PAST, PRESENT, AND FUTURE ECOSYSTEM FUNCTIONS? THIS PROJECT WILL FURTHER INDICATE HOW WE CAN USE KNOWLEDGE OF THESE RELATIONSHIPS TO INFORM MORE JUST, TRANSFORMATIVE, AND SUSTAINABLE FUTURES. BROADER SOCIETAL IMPACTS ARE INTENTIONALLY INTEGRATED IN CAP V RESEARCH, WITH MANY ACTIVITIES INVOLVING EXPLICIT PARTNERSHIPS WITH PRACTITIONERS AND COMMUNITIES THAT HISTORICALLY HAVE HAD LITTLE VOICE IN THE FUTURE OF THEIR CITY AND ENVIRONMENT. THIS WORK FORMS A TRANSLATIONAL LINK AMONG SOCIAL-ECOLOGICAL RESEARCH OUTCOMES, CITY INSTITUTIONS, AND COMMUNITIES WITH THE GOAL OF ULTIMATELY MAKING PHOENIX, AND CITIES IN GENERAL, BETTER AND MORE SUSTAINABLE PLACES TO LIVE. CAP RESEARCH WILL EXTEND ITS FOCUS ON THE THEORY OF URBAN ECOLOGICAL INFRASTRUCTURE (UEI) AS A CRITICAL BRIDGE BETWEEN THE SYSTEM?S BIOPHYSICAL AND HUMAN/SOCIAL DOMAINS. CAP RESEARCHERS WILL CONTINUE TO EXPLORE INTERDISCIPLINARY URBAN ECOLOGY IN RESIDENTIAL LANDSCAPES, URBAN WATERBODIES, DESERT PARKS AND PRESERVES, WHILE EXAMINING THE PLANTS, ANIMALS, CLIMATE, URBAN DESIGN AND GOVERNANCE ACROSS THE METROPOLITAN PHOENIX REGION. NEW RESEARCH INITIATIVES WILL INCLUDE A FOCUS ON ENVIRONMENTAL JUSTICE AND EQUITY, AS WELL AS URBAN AIR QUALITY. THE RESEARCH WILL DEVELOP BOTH KNOWLEDGE AND SOLUTIONS IN UNDERSERVED AND HISTORICALLY NEGLECTED COMMUNITIES, INCLUDING LOCAL INDIGENOUS COMMUNITIES. CAP V RESEARCH IS ORGANIZED AROUND FIVE INTERDISCIPLINARY AREAS: 1) ECOSYSTEM STRUCTURE AND FUNCTION AND BIOGEOCHEMICAL CYCLING; 2) ADAPTATION AND ECO-EVOLUTIONARY DYNAMICS; 3) URBAN CLIMATE, AND AIR QUALITY; 4) URBAN NATURE AND HUMAN PERCEPTIONS, DECISIONS, AND WELLBEING; AND 5) ENVIRONMENTAL JUSTICE, GOVERNANCE, AND TRANSFORMATIVE FUTURES. INVESTIGATING THESE QUESTIONS, IN THE CONTEXT OF THE PREVIOUS 25 YEARS OF CAP RESEARCH, WILL GUIDE THE CAP RESEARCH ENDEAVOR TOWARDS MORE SUSTAINABLE AND RESILIENT FUTURES FOR U.S. CITIES AND FOR OUR INCREASINGLY URBAN SOCIETY. THIS AWARD IS JOINTLY FUNDED BY THE DIVISION OF ENVIRONMENTAL BIOLOGY AND THE DIVISION OF BEHAVIORAL AND COGNITIVE SCIENCES. THIS AWARD REFLECTS NSF'S STATUTORY MISSION AND HAS BEEN DEEMED WORTHY OF SUPPORT THROUGH EVALUATION USING THE FOUNDATION'S INTELLECTUAL MERIT AND BROADER IMPACTS REVIEW CRITERIA.

RESEARCH BASE PERIOD (PHASE I)--

UNIVERSITY PARTNERSHIPS FOR TACTICAL AI CYBERSECURITY (UPTAIC) PROGRAM

OUR PROPOSED CUBESAT OBSERVATORY THE STAR-PLANET ACTIVITY RESEARCH CUBESAT (SPARCS) WILL BE THE FIRST MISSION TO PROVIDE THE TIMEDEPENDENT SPECTRAL SLOPE

NSF-SFS: ARIZONA CYBER DEFENSE SCHOLARSHIP

NNCI: NANOTECHNOLOGY COLLABORATIVE INFRASTRUCTURE SOUTHWEST (NCI-SW)

PRECISION MEDICINE IN ALZHEIMER?S DISEASE: A SMART TRIAL OF ADAPTIVE EXERCISES AND THEIR MECHANISMS OF ACTION USING AT(N) BIOMARKERS TO OPTIMIZE AEROBIC-FITNESS RESPONSES - ABSTRACT AEROBIC EXERCISE IS A PROMISING TREATMENT FOR ALZHEIMER’S DISEASE (AD) AND AD-RELATED DEMENTIA (ADRD), BUT EXERCISE TRIALS HAVE SHOWN MIXED EFFECTS ON COGNITION, PHYSICAL FUNCTION, BEHAVIORAL AND PSYCHOLOGICAL SYMPTOMS OF DEMENTIA (BPSD), QUALITY OF LIFE (QOL), AND CAREGIVER BURDEN. THESE FINDINGS ARE LIKELY DUE TO INDIVIDUAL DIFFERENCES IN AEROBIC-FITNESS RESPONSES, LONG ESTABLISHED IN ADULTS USING PEAK OXYGEN CONSUMPTION (VO2PEAK) AND FIRST REPORTED IN OLDER ADULTS WITH ADRD BY OUR TEAM. AD/ADRD EXERCISE TRIALS REPORT LARGE VARIANCE IN VO2PEAK CHANGES FROM MODERATE-INTENSITY CONTINUOUS TRAINING (MICT). MECHANISTICALLY, ANIMAL STUDIES SUPPORT AEROBIC EXERCISE MODIFYING AD’S AT(N) BIOMARKERS (AMYLOID-BETA [ASS], TAU, AND NEURODEGENERATION), BUT SIMILAR HUMAN STUDIES ARE RARE. HENCE, PRECISION EXERCISE IS CRITICAL TO IDENTIFY MICT NON-RESPONSE EARLY TO INITIATE ALTERNATIVE INTERVENTIONS (HIGH INTENSITY INTERVAL TRAINING [HIIT] OR COMBINED AEROBIC AND RESISTANCE EXERCISE [CARE]). BECAUSE VO2PEAK CAN IMPROVE AND PEAK FROM 3-MONTH MICT, IT IS LOGICAL TO USE VO2PEAK AT 3 MONTHS TO IDENTIFY NON-RESPONSE AND INITIATE HIIT OR CARE. THIS PHASE II, PILOT TRIAL WILL BE A SEQUENTIAL, MULTIPLE ASSIGNMENT, RANDOMIZED TRIAL. ITS PURPOSE IS TO TEST THE EFFECTS OF 6-MONTH AEROBIC EXERCISE ON AEROBIC FITNESS AND ITS MECHANISMS OF ACTION IN COMMUNITY-DWELLING OLDER ADULTS WITH MILD AD DEMENTIA. OUR CENTRAL HYPOTHESIS IS THAT MICT AUGMENTED WITH HIIT OR CARE WILL IMPROVE AEROBIC FITNESS, WHITE MATTER HYPERINTENSITY (WMH), AND PLASMA BIOMARKERS, WHICH UNDERLIE EXERCISE’S COGNITIVE EFFECTS. THIS TRIAL BUILDS ON OUR PREVIOUS WORK SHOWING: SUCCESSFUL RECRUITMENT, RETENTION, ADHERENCE, AND SAFETY; 6-MONTH MICT MAINTAINED MEMORY AND REDUCED WMH; INDIVIDUAL DIFFERENCES IN VO2PEAK AND COGNITIVE RESPONSES TO MICT; MICT IMPROVED PHYSICAL FUNCTION, QOL, AND CAREGIVER DISTRESS; PLASMA NEUROFILAMENT LIGHT CHAIN (NFL) PREDICTED COGNITION; AND MICT AFFECTED PLASMA P-TAU181. IT WILL RANDOMIZE 108 PARTICIPANTS 2:1 TO 3-MONTH MICT OR 6-MONTH STRETCHING CONTROL AFTER BASELINE. VO2PEAK WILL BE ASSESSED AFTER 3-MONTH MICT TO IDENTIFY NON- RESPONDERS (<5% INCREASE) AND RE-RANDOMIZE THEM 1:1 TO HIIT OR CARE FOR 3 MONTHS. RESPONDERS WILL CONTINUE MICT FOR 3 MONTHS. PARTICIPANTS WILL BE FOLLOWED FOR ANOTHER 6 MONTHS. PRIMARY OUTCOMES ARE AEROBIC FITNESS MEASURED AT 0, 3, 6, 9, AND 12 MONTHS AND WMH VOLUME AT 0, 6, AND 12 MONTHS. SECONDARY OUTCOMES (MEMORY, PHYSICAL FUNCTION, BPSD, QOL, CAREGIVER BURDEN) AND PLASMA ASS42/40, P-TAU181, T-TAU, AND NFL WILL BE ASSESSED AT 0, 3, 6, 9, AND 12 MONTHS. THIS TRIAL HAS 80% POWER FOR ALL PRIMARY HYPOTHESES, ASSUMING 18% AND 25% ATTRITION AT 6 AND 12 MONTHS, RESPECTIVELY. THE SPECIFIC AIMS ARE TO: I) TEST THE EFFECTS OF AEROBIC EXERCISE ON AEROBIC FITNESS, WMH VOLUME, AND PATIENT-CENTERED OUTCOMES IN OLDER ADULTS WITH MILD AD DEMENTIA; II) THE BEST EXERCISE TO IMPROVE AEROBIC FITNESS AND REDUCE NON-RESPONSES OVER 6 MONTHS IN OLDER ADULTS WITH MILD AD DEMENTIA; AND III) EXAMINE THE MECHANISMS OF AEROBIC EXERCISE’S ACTION ON MEMORY IN MILD AD DEMENTIA. THIS TRIAL IS THE FIRST PRECISION-EXERCISE TRIAL IN AD, AND WILL UTILIZE MRI/BLOOD BIOMARKERS, WHICH ARE SCALABLE.

PREPARING LEADERS ON EDUCATION, DISABILITY, AND JUVENILE JUSTICE (PLEDJJ)

THIS AWARD FUNDS THE APPROVED 2022?23 PUBLIC HEALTH AMERICORPS PROGRAM. NO MEMBER MAY ENROLL PRIOR TO THE APPROVED START DATE OF THE MEMBER ENROLLMENT PERIOD. YOUR 2022?23 REGULATORY MATCH IS 0%. THE ARIZONA STATE UNIVERSITY PROPOSES TO HAVE 99 AMERICORPS MEMBERS WHO WILL BUILD CAPACITY FOR RESPONDING TO INTIMATE PARTNER VIOLENCE WITHIN STATE AND LOCAL PUBLIC HEALTH AND COMPLIMENTARY AGENCIES IN ARIZONA, FLORIDA, INDIANA, KANSAS, KENTUCKY, MASSACHUSETTS, NEW YORK, NORTH CAROLINA, OHIO, PENNSYLVANIA AND TEXAS. AT THE END OF THE FIRST PROGRAM YEAR, THE AMERICORPS MEMBERS WILL BE RESPONSIBLE FOR INCREASING PUBLIC HEALTH PRACTITIONERS' KNOWLEDGE, ATTITUDES, AND PERCEIVED READINESS TO RESPOND TO INTIMATE PARTNER VIOLENCE SURVIVORS. IN ADDITION, THE AMERICORPS MEMBERS WILL LEVERAGE APPROXIMATELY 74 VOLUNTEERS, WHO WILL BE ENGAGED IN INTEGRATING THE MEMBER INTO THE PUBLIC HEALTH AND COMPLIMENTARY AGENCIES. AFTER THEIR YEAR OF SERVICE, 60 AMERICORPS MEMBERS WILL PURSUE FUTURE ENGAGEMENT IN THE PUBLIC HEALTH SECTOR.

FRAMEWORKS: COLLABORATIVE RESEARCH: INTEGRATIVE CYBERINFRASTRUCTURE FOR NEXT-GENERATION MODELING SCIENCE

A CONCEPTUAL EFFICACY REPLICATION OF THE TELL PRESCHOOL CURRICULUM WITH WEB-BASED IMPLEMENTATION SUPPORT AND PROFESSIONAL DEVELOPMENT VARIATIONS

GCR: RATIONAL DESIGN OF TOPOLOGICAL INSULATORS USING ATOMICALLY-PRECISE DNA SELF-ASSEMBLY -IN MANY WAYS THE HISTORY OF HUMANITY IS THE HISTORY OF MATERIALS; FROM THE BRONZE AND IRON AGES TO THE MODERN SILICON AGE, HUMANS HAVE TAKEN ADVANTAGE OF THE PROPERTIES OF THE MATERIALS AROUND THEM TO FOSTER THE ADVANCEMENT OF CIVILIZATION. FROM THIS VIEWPOINT, THE PINNACLE OF IMPROVEMENT WOULD BE TO DESIGN MATERIALS WITH DESIRED PROPERTIES A PRIORI. THE VISION OF THIS CONVERGENT PROJECT IS TO ADDRESS THIS GRAND CHALLENGE. THIS PROJECT AIMS TO TAKE ADVANTAGE OF THE UNIQUE CHARACTERISTICS OF DNA SELF-ASSEMBLY, ALONG WITH ITS CHEMICAL AND STRUCTURAL PROPERTIES TO CREATE SYNTHETIC MATERIALS WITH PRECISELY-CONTROLLABLE ELECTRONIC AND MAGNETIC PROPERTIES WITH THE ULTIMATE GOAL OF DEVELOPING MAGNETIC TOPOLOGICAL INSULATORS (TIS). THE INTRODUCTION OF ROBUST MAGNETISM INTO TIS WILL ALLOW UNIQUE QUANTUM PHENOMENA TO BE REALIZED IN THE SOLID STATE THAT COULD BE EXPLOITED FOR APPLICATIONS INCLUDING QUANTUM COMPUTING, ELECTRONICS, SPINTRONICS, OPTOELECTRONICS, AND RENEWABLE ENERGY. ACCOMPLISHING THIS VISION WILL REQUIRE A CONVERGENCE BETWEEN CHEMISTRY, BIOLOGY, MATERIALS SCIENCE, ENGINEERING, NANOTECHNOLOGY, COMPUTATIONAL MODELING, AND CONDENSED MATTER PHYSICS. TO ACHIEVE CONVERGENCE, THIS PROJECT BRINGS TOGETHER A DIVERSE TEAM OF EXPERTS SPANNING THESE DISCIPLINES THAT WILL WORK COLLABORATIVELY TO CO-DESIGN AND CO-DEVELOP THESE SYSTEMS. DEVELOPING THE ABILITY TO PRECISELY CONTROL THE ELECTRONIC BAND STRUCTURE AND MAGNETIC PROPERTIES OF MATERIALS WILL HAVE BROAD IMPACTS ACROSS SOCIETY IN THE COMING DECADES. IN ADDITION, THIS PROJECT INCLUDES A FRAMEWORK FOR NUCLEATING A NEW SCIENTIFIC COMMUNITY FOCUSED ON UTILIZING THE UNIQUE SPATIAL AND TOPOLOGICAL PROPERTIES OF SOFT MATTER TO CREATE TOPOLOGICAL INSULATORS WITH PRECISELY TAILORED ELECTRONIC AND MAGNETIC PROPERTIES. THIS COMMUNITY WILL REPRESENT A CONVERGENCE OF THOUGHTS, LANGUAGE, AND IDEALS FROM A BROAD SPECTRUM OF THE SCIENCE AND ENGINEERING COMMUNITY. THIS PROJECT AIMS TO DEVELOP A FRAMEWORK THAT ENABLES PRECISION TOPOLOGICAL CONTROL OVER THE ELECTRONIC AND MAGNETIC PROPERTIES OF MATERIALS. ACHIEVING THIS VISION REQUIRES A CONVERGENCE BETWEEN COMPLEMENTARY DISCIPLINES TO ULTIMATELY FUSE THE REALMS OF SOFT MATTER, REAL-SPACE TOPOLOGY WITH MOMENTUM-SPACE (K-SPACE) TOPOLOGY. SPECIFICALLY, THE AIM IS TO UTILIZE THE UNIQUE PROGRAMMABILITY AND UNPARALLELED SPATIAL, STRUCTURAL, AND SELF-ASSEMBLY CAPABILITIES AFFORDED BY DNA NANOTECHNOLOGY TO PRECISELY TAILOR THE TOPOLOGY OF METAL IONS TO ULTIMATELY CREATE MAGNETIC TOPOLOGICAL INSULATORS THROUGH ITERATIVE, RATIONAL DESIGN. THE INTRODUCTION OF MAGNETISM INTO TOPOLOGICAL INSULATORS IS CURRENTLY A MAJOR UNRESOLVED CHALLENGE IN THE CONDENSED MATTER PHYSICS COMMUNITY; AND REAL-SPACE, DNA-BASED TOPOLOGICAL CONTROL PROVIDES A UNIQUE PATH TOWARD SOLVING THIS CHALLENGE. THE DEVELOPMENT OF ATOMICALLY PRECISE, METALATED DNA MOTIFS WILL ALLOW CONTROL OVER ELECTRONIC PROPERTIES, AND THE DESIGN OF PURPOSE-SPECIFIC, SELF-ASSEMBLED BAND STRUCTURE. TO ACHIEVE THIS GOAL, THIS PROJECT WILL FOCUS ON: I) ADVANCING CHEMICAL DESIGN AND SYNTHESIS OF METALATED BASE PAIRS AT THE ATOMIC AND MOLECULAR LEVELS; II) DEVELOPING APPROACHES FOR THE STRUCTURAL AND TOPOLOGICAL DESIGN OF DNA ASSEMBLIES AT THE SUPRAMOLECULAR SCALE; III) EXTRACTING AND QUANTIFYING THE ELECTRONIC PROPERTIES OF SMALL-SCALE DNA-BASED ASSEMBLIES; IV) MODELING THE ELECTRONIC STRUCTURE AND TRANSPORT PROPERTIES OF HYBRID BIO/CONDENSED MATTER AT THE MOLECULAR LEVELS; V) DEVELOPING A DESIGN LANGUAGE FOR UNDERSTANDING HOW TO MAP THE UNIQUE SPATIAL TOPOLOGICAL CONTROL AFFORDED BY DNA NANOTECHNOLOGY INTO THE DESIRED MOMENTUM-SPACE TOPOLOGICAL CONTROL OF ELECTRONS IN TOPOLOGICAL INSULATORS. THROUGH THESE STEPS, THIS PROJECT WILL DESIGN AND IMPLEMENT INITIAL PROOF-OF-PRINCIPLE TI DESIGNS AND PLANT THE SEEDS OF A NEW COMMUNITY THAT WILL SUSTAIN THIS NASCENT FIELD IN THE DECADES TO COME. THIS AWARD REFLECTS NSF'S STATUTORY MISSION AND HAS BEEN DEEMED WORTHY OF SUPPORT THROUGH EVALUATION USING THE FOUNDATION'S INTELLECTUAL MERIT AND BROADER IMPACTS REVIEW CRITERIA.- SUBAWARDS ARE PLANNED FOR THIS AWARD.

22-ICAR22_2-0016 TRACING ROCKY EXOPLANET COMPOSITIONS